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Malignant tumors exhibit abnormal DNA methylation - following a pattern differing significantly from that of healthy tissue - at a very early stage in tumorigenesis and during tumor progression. In general, genome-wide methylation in tumor cells decreases (genome-wide hypomethylation), while individual genes are hypermeth-ylated (gene-specific ...
Stem cells have been considered to have tremendous potential for biological and therapeutic applications, because of their self-replicating ability and differentiation into multiple types of cells. ...
Stem cells have been considered to have tremendous potential for biological and therapeutic applications, because of their self-replicating ability and differentiation into multiple types of ...