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Simple ; The SentinusAl platform performs antibody affinity optimization based on sequences only. Fast ; SentinusAI searches over a 10^10 mutations at 10,000x speed. Humanized ; SentinusAI replaces immunogenic residues with non-immunogenic residues. ...
The CHARMM General Force Field program generates comprehensive parameters and topology information for a wide range of drug-like molecules, allowing their use in computer-aided drug design campaigns. ...
Molecular docking is a structure-based drug design method that predicts the binding mode and affinity by studying the interaction of organic small molecule ligands with biological macromolecular receptors. Molecular docking methods have a wide range of applications in the fields of enzymology research and drug design. https://www.computabio.com/principles-of-molecular-docking.html ...
RTSM Master delivers powerful randomization methods that, when combined with our fully validated and configurable trial modules, can perform robust subject screening and randomization, clinical supply management and investigational product assignments at designated drug dispensing visits. RTSM Master's randomization simulator can validate and support your testing and assumptions of ...
Simple : CarbonAI searches over 1.9 billion compounds to create synthesizable drug candidates – based only on target sequence. Precise : CarbonAI accurately identifies the most active and safe compound with a multi-objective optimization algorithm. ...
Auris Medical is developing Sonsuvi for the treatment of acute inner ear (sensorineural) hearing loss (ASNHL). Sonsuvi contains brimapitide, or D-JNKI-1 (D-stereoisomer of c-Jun N-Terminal Kinase Inhibitor 1), an inhibitor of the JNK stress kinase coupled to an intracellular transporter. Sonsuvi is formulated in a biocompatible and fully biodegradable gel and administered in a single dose ...
