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The strategies of heart-targeted drug delivery refer to the direction of active agents and their carriers into the affected tissue with minimal effects on surrounding healthy tissues after systemic administration. The efficacious delivery of drugs to the heart is an important treatment strategy for various heart ...
DSPE-PEG-maleimide (DSPE-PEG-MAL) is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce nonspecific protein binding or cell adhesion, and the reactive maleimide to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide. ...
Organ-specific drug targeting has already been explored as a possible alternative to surgery to treat prostate diseases. The strategies of prostate-targeted drug delivery refer to the direction of active agents and their carriers into the affected tissue with minimal effects on surrounding healthy tissues after systemic administration. ...
Gene Panel has been an invaluable tool to analyze parallel gene expression for disease-associated mutations. Here we present four powerful non-NGS technologies for gene panel that can promote your disease research, biomarker discovery, and targeted drug development. https://www.cd-genomics.com/diseasepanel/non-ngs-panel.html ...
Biosafety is the major concern in clinical translation of nanomedicine. As an intrinsic ingredient of human blood without immunogenicity and the emphasis on its successful clinical application in Abraxane, albumin has been considered as a promising material to produce nanoparticles for bioimaging and drug ...
The Disease Panel provides one-stop solutions (including both services and reagents) for the study of a wide range of diseases, including cancer, inherited disease, and infection by using NGS panels or non-NGS panels, which facilitate numerous applications such as disease research, biomarker discovery, and targeted drug development. https://www.cd-genomics.com/diseasepanel/custom-ngs-panel.html ...
Cypre’s 3D Tumor Models combine the tumor, stromal and immune compartments in a high throughput format to screen targeted drugs and immunotherapy. In 2021, we partnered with Charles River to offer our 3D Tumor Models for drug discovery and preclinical screening services. ...
COVID-19 Research: Antiviral Drug Target ? The COVID-19 pandemic is caused by infection of SARS-CoV-2 or severe acute respiratory syndrome coronavirus 2, a positive-sense single-stranded RNA virus. The RNA dependent RNA polymerase (RdRp) is a key drug target for this deadly virus. The gel-based SARS-CoV-2 RdRp assay can be used for visualization of the RNA molecules synthesized by the RNA ...
CD Genomics has developed a specialized platform for targeted sequencing of disease-related genes to accelerate research on disease pathogenesis, disease identification, biomarker discovery, targeted drug development, etc. More can be reached at https://www.cd-genomics.com/diseasepanel/predesigned-ngs-panel.html ...
This document explores cutting-edge advancements in healthcare, including multifunction armchairs for enhanced patient comfort, spinal navigation for precise surgical guidance, cervical mapping for advanced diagnostics, and advanced drug delivery systems for targeted treatment. These innovations improve patient outcomes, surgical accuracy, and overall medical efficiency, shaping the future of ...
Comprehensive suite of new pre-clinical and clinical testing capabilities: pharmacokinetic (PK), pharmacodynamic (PD), and companion diagnostic (CDx) services. Proteomics International applies its proven expertise and experience in targeted mass spectrometry to the field of PK testing. Mass spectrometry is ideal for the accurate and precise quantitation of target drugs and their break-down ...