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Annexin A5 is a host cell protein (HCP) generated by CHO cells during production of biotherapeutics. This process-related impurity accumulates in the extracellular space as it is released from dead CHO cells and secreted from viable cells during cell culture. Annexin A5 is highly immunogenic and may cause dangerous adverse reactions if present in a therapeutic drug formulation. Purified ...
Ridaforolimus Eluting Coronary Stent System; Excellent clinical outcomes. Redefining deliverability with a new spring tip. Low footprint cobalt-chromium design. Optimal conformability and vessel support. Elastomeric coating and outstanding surface integrity. Eluting Ridaforolimus, a high therapeutic index limus drug. ...
ByMedinol
Over the past two decades great improvements in therapy of chronic inflammatory diseases have been made. The rise of TNFα biologics like infliximab has been a significant step forward to ameliorating disease course and keeping inflammations at remission levels for prolonged periods of time. Patients with too low drug concentrations have worse outcomes than those with adequate drug levels. ...
Multichem IA contains 83 analytes including fertility and thyroid hormones, steroid hormones, cardiac markers, anaemia markers, therapeutic drugs, adrenal markers and bone metabolism ...
Over the past two decades great improvements in therapy of chronic inflammatory diseases have been made. The rise of anti TNFα biologics has been a significant step forward to ameliorating disease course and keep inflammations at remission levels for prolonged periods of time. Adalimumab is the first anti TNFα biologic on the market approved for patient self-administration by ...
OncoPeptTUME — A novel in-silico approach to model the tumor microenvironment and predict treatment efficacy and long-term survival benefits for immunotherapy applications. Cancer immunotherapy is now established as a major therapeutic modality. Cancer immunotherapy drugs elicit their anti-tumor immune response in a subset of the treated patients by activating CD8 T-cells and provide ...