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SARS-CoV-2 neutralizing antibodies (nAbs) are special antibodies that function to prevent SARS CoV-2 from binding to the ACE2 receptor of human cells. High levels of nAbs indicate immunity against COVID-19. Standard IgG/IgM antibody tests – which are universally available – do not detect for nAbs and can only provide an indirect indication for immunity. A SARS-CoV-2 nAb test can be ...
Immunogenicity assays play a vital role in evaluating the safety and efficacy of vaccines by measuring the immune response induced in vaccinated individuals, and serve as crucial tools in vaccine development, clinical trials, licensure, and post-marketing surveillance. Various methods are employed in vaccine immunogenicity assays, ranging from traditional techniques like LBAs to advanced ...