MedGenome - TCR Sequencing Service - Brochure

TCR profiling holds great potential not only for understanding the mechanisms of development of the normal immune response, but also in providing insights into disease mechanisms and development of new therapeutics and treatment modalities in infectious diseases, autoimmunity and in immuno-oncology. However, identification of all potential clonotypes in a diverse repertoire of TCRs requires sensitive methods of detection. Next-generation sequencing (NGS) technologies have recently enabled accurate detection of TCRs, and in combination with other assays, allow for the assessment of the TCR repertoire in patients which in turn is a proxy for patient prognosis and response. At MedGenome, we provide RNA based TCR repertoire profiling services for bulk and single cell analysis.