Medical Diagnostics Articles
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A breath screen for active tuberculosis at the point-of-care
Tuberculosis (TB) is on the rise, and traditional technologies are not up to the task of containing this fast-spreading disease. But a fast, robust, and low-cost optical system is enabling point-of-care testing Driven by various social factors, a number of “old” diseases have recently reemerged to significantly threaten world health. Of particular concern is the increase in ...
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CanaQuest Medical Corp (OTC: CANQF)
About: CanaQuest Medical is an award-winning, Clinical Stage/Life-Sciences company focused on the drug discovery and development of next-generation targeted therapeutics within the endocannabinoid system and specific brain receptors. The Company is focused on treating neurological conditions, such as epilepsy, anxiety, depression, and Post Traumatic Stress Disorder “PTSD,” including ...
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VIE in Emerging Applications - Case Study
Patient History 83 year old male with no history of esophageal disease. The patient was referred to Dr. Singh after a possible esophageal mass was noted as an incidental finding during a CT scan for an unrelated ...
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VLE for Post-Treatment Assessment - Case Study
Patient History This patient was originally referred with nodular esophageal disease that was endoscopically visible at the Castro-Esophageal Junction (CEJ). The area was treated using combination Cryotherapy and Endoscopic Mucosal Resection (EMRJ. (Figures 1-3) Pathology of the EMR sample was positive for Adenocarcinoma (Figure 4) A subsequent surveillance ECD showed the previous EMR site, a ...
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VLE for Pre-Treatment Planning - Case Study
Patient History A 68 year old male being treated for short segment (1cm) Barrett's Esophagus (BE). During a prior exam, combination therapy for recurring non-dysplastic BE by Endoscopic Mucosal Resection (EMR) and Radiofrequency Ablation (RFA) was conducted. The intent for this procedure was to assess the treatment area, in part, using the NvisionVLE Imaging System, and to ablate any recurrence ...
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VLE for Identification of Subsquamous Disease - Case Study
Patient History This patient was a 68 year old man referred with short segment Barrett's Esophagus (BE) with intramucosal carcinoma (IMC). At the referring center, previous resection of nodularity revealed Tla adenocarcinoma with negative margins. Subsequent surveillance biopsies yielded IMC, and triggered referral. For the procedures described here, standard endoscopy with the addition of ...
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Artificial intelligence meets human intelligence to collaborate on addressing brain health
Researchers agree that early detection is the key to optimising the potential success of drug and device therapies – and that these therapies would work most effectively if they were administered when a patient first begins to develop a disease rather than waiting until when they are displaying obvious symptoms. However, it is extremely difficult to observe exactly when this process starts ...
By nQ Medical
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Catalase, a Common Antioxidant Enzyme
Catalase is an antioxidant enzyme commonly found in almost all living organisms, mainly in chloroplasts, mitochondria, endoplasmic reticulum of plants, liver and red blood cells of animals. It is the marker enzyme of the peroxisome, accounting for about 40% of the total peroxisomal enzymes. Catalase is a homotetramer composed of four polypeptide chains, each containing more than 500 amino acid ...
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Self-amplifying RNA as a tool to tackle emerging flavivirus outbreaks: lessons learned from the COVID-19 pandemic
Background Outbreaks of multiple Flaviviruses have afflicted humankind for centuries due to their rapid spread predominantly by arthropod vectors. Global warming has caused epidemics to emerge in previously unaffected regions. The SARS-CoV-2 outbreak and subsequent race in vaccine development can provide strategies to the scientific community to avoid a flavivirus pandemic. The COVID-19 battle ...
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Decreasing Benign Breast Ultrasound Biopsies: Prospective Use of AI Decision Support
After implementation of AI decision support, the benign biopsy rate decreased from 71.79% to 59.2% while the overall biopsy rate stayed constant. PPV3 increased from 28.2% to 40.8%. Objective To examine the affect of prospective AI decision support (Koios DS Breast) use on breast ultrasound biopsy performance metrics. Materials and Methods Non-identifiable HIPAA compliant data collected ...
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Applications of Diamine Oxidase
Diamine oxidase (DAO) is an intracellular enzyme that catalyzes diamine in mucosal or ciliated epithelial cells of the mammalian small intestine. It protects the intestinal mucosa by regulating intracellular ion homeostasis, influencing conduction pathways, and promoting cellular repair. Serum DAO is elevated in small intestinal mucosal barrier failure or in intestinal mucosal cell necrosis; ...
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Everything You Want to Know About Lipoprotein Lipase
Lipoprotein lipase (LPL) is a glycoprotein synthesized and secreted by parenchymal cells such as adipocytes, cardiomyocytes, skeletal muscle cells, mammary cells, and macrophages, with a molecular weight of 60ku and containing 3-8% carbohydrates. The physiological function of LPL is to catalyze the breakdown of TG in the core of CM and VLDL into fatty acids and monoglycerides for tissue oxidative ...
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Pressure Ulcer - Case study
Patient History Patient presented with a history of hypertension, hyperlipidemia, peripheral arterial disease, obesity, arterial fibrillation, and transient ischemic attack. Patient had total knee replacement surgery and developed a complication due to improper off-loading, developing pressure ulcer on the right heel. Patient was treated with collagen products and wet to dry dressings prior to ...
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Distal Radius & Distal Ulna Fractures - Case Study
In this case, we see the preoperative radiographs of a 70-year-old, independent woman with medical comorbidities. Stability was achieved under local MAC, utilizing minimally invasive T-Pin ...
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Organic Acids Analysis
The organism undergoes thousands of biochemical reactions every moment to maintain our growth, development and energy metabolism. Under normal circumstances, these biochemical reactions proceed smoothly step by step through various cycles or certain steps. The process by which the body changes carbohydrates, amino acids, and fats from nutrients to absorbable substances and wastes is called the ...
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Features, Principles and Benefits of BioID
Features of BioID Biotin is a naturally occurring metabolic enzyme cofactor that is active only when covalently linked to the enzyme by the action of a specific protein-biotin ligase. Any biotinylated substrate can bind tightly to protein affin and streptavidin. Its main advantages include: 1. High sensitivity - The affinity between biotin and streptavidin (Kd=10-15 mol/L) is >1,000-fold ...
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Intraoperative Identification and Monitoring of the Somatic Nerves Critical to Potency Preservation during da Vinci Prostatectomy
Background Since Walsh and Donker first introduced the anatomic nerve-sparing technique for retropubic radical prostatectomy1 (RRP) in the treatment of clinically localized prostate cancer, the importance of minimizing damage to the neurovascular bundle (NVB) has been recognized as a critical element for the preservation of potency and urinary continence post-prostatectomy. Although originally ...
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New Screening Solution Offers Hope in the Battle Against TB
In recent years, a number of ‘old’ diseases have re-emerged as significant threats to world health, driven by factors such as population migration and modern transportation. Of particular concern is the increase in the incidence of tuberculosis (TB) infection, a highly contagious disease spread through the air when infected people cough, sneeze or spit. According to statistics ...
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Results of Using a New Technology to Improve the Identification and Preservation of Nerve Tissue during Robotic-Assisted Laparoscopic Radical Prostatectomy
Introduction & Objectives Efforts to improve continence after robotic-assisted laparoscopic radical prostatectomy (RALRP) have focused on preserving periurethral and bladder neck tissue and techniques involving posterior reconstructions and anterior suspensions. Many patients, however, still have varying degrees of urinary incontinence. Literature has shown that nerves innervating the levator ...
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Microbot Medical Attracts Another Leading Physician and Expands Capabilities of its Scientific Advisory Board with Addition of Dr. Ripal Gandhi
HINGHAM, Mass., Sept. 19, 2022 (GLOBE NEWSWIRE) -- Microbot Medical Inc. (Nasdaq: MBOT), continuing its recent success of strengthening its Scientific Advisory Board with the recent recruitment of Key Opinion Leaders (KOLs), today announced that Ripal T. Gandhi, MD, FSVM, will join the Company’s robust Scientific Advisory Board (SAB). Dr. Gandhi is an interventional oncologist and a member ...
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