Medical Diagnostics Articles
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Bio-Ink: Printing the Future of Medicine and Beyond
Bio-ink is a revolutionary material that is rapidly changing the fields of medicine, tissue engineering, and even bioprinting food. This fascinating substance is essentially a type of ink made from living cells and other biocompatible materials that can be used to 3D print complex biological structures. What is Bio-Ink Made Of? The composition of bio-ink can vary depending on the desired ...
By Matexcel
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Four Novel Drug Delivery Systems You Should Know
In the field of medicine, effectively delivering drugs to the target site in the body is crucial for successful treatment. Over the years, several innovative drug delivery systems have been developed to improve drug efficacy and patient outcomes. In this article, we will discuss four novel drug delivery systems that have shown promising results in recent research. These systems include ...
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Homologous Recombination-mediated Genome Editing Service
As a global leader in recombination-mediated genome editing service, Creative Biogene is dedicated to provide a number of services to achieve scientific results faster than ever before. We have a team of passionate and talented scientists who have years of experience and would work closely with you to provide help in reducing your workload while raising the visibility of your research. In ...
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CMC Regulatory Considerations for ADCs
Antibody drug conjugates (ADCs) are a new class of biopharmaceuticals that use monoclonal antibodies to target tumor cells to deliver potent cytotoxic drugs. So far, a total of 15 ADC drugs have been approved worldwide, of which the FDA has approved 13 ADCs for various cancers, including Adcetris®, Kadcyla®, Besponsa®, Mylotarg®, Lumoxiti®, Polivy®, Padcev®, Enhertu ®, Trodelvy® and Blenrep®. As ...
By BOC Sciences
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Antibody-Drug Conjugates: New Strategies of ADC Payloads
The concept of ADCs was first proposed by Nobel Prize winner Paul Ehrlich in 1913. But it was not until 1975, when hybridoma technology began to be used to produce monoclonal antibodies, that the era of ADC drug development truly began. Driven by increasingly mature technology, ADC drugs have gone through three iterations (Fig. 1). Although ADCs have gone through three iterations, current ...
By BOC Sciences
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Wound Care Nurse Teaching:DOs and DON'Ts for Wounds Healing
Introduction Nursing the wounds is something we all need to think about, whether it's dealing with a little cut from a DIY project at home, a tumble outdoors, or a surgical procedure. And as the body get age, the skin wounds become more frequent. It's time to understand the advantage wound care for for optimal healing. This article offersexpert-approved advice to help you manage different types ...
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How Proper Packaging Improves the Shelf Life of Medical Devices
Medical devices are incredibly important in today’s world. They play a significant role in the treatment and prevention of various medical conditions. However, their effectiveness can be compromised if they are not packaged correctly. Packaging is an essential component of maintaining the integrity and shelf life of medical devices, especially during transportation and storage. Read on ...
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Speeding Up Healthcare Innovation Leveraging Cloud Technology
Over the past decade, cloud computing has undergone remarkable expansion. The collective revenue generated by AWS, Google Cloud, and Microsoft surged from $49 billion in 2018 to an astonishing $206 billion in 2022.[i] Projections from Future Market Insights indicate that the revenue from cloud services is poised to maintain an impressive average annual growth rate of 21%, reaching a staggering ...
By Caresyntax
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What Material Is PP Plastic?
PP plastic refers to plastic made of polypropylene (PP for short). Polypropylene is a thermoplastic polymer, a synthetic plastic made by polymerizing propylene monomer. During the polymerization process, the molecular structure of propylene monomers are repeatedly connected to form polymer chains, ultimately forming polypropylene. PP is a very common and versatile plastic with many excellent ...
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Co-Immunoprecipitation (Co-IP): A Comprehensive Guide
Introduction Co-immunoprecipitation (Co-IP) is a versatile and powerful laboratory technique employed to elucidate protein-protein interactions. It is particularly valuable for identifying and characterizing protein complexes involved in various cellular processes. The technique relies on the specificity of antibodies to selectively capture a protein of interest (bait) from a complex mixture, ...
By Profacgen
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Protein Engineering: Designing Molecular Machines for a Healthier Future
Proteins are the workhorses of life, performing a vast array of essential functions, from catalyzing biochemical reactions to building and maintaining cellular structures. Protein engineering, a rapidly evolving field at the intersection of biology, chemistry, and computer science, aims to harness the power of these molecular machines by designing and manipulating their structure and function to ...
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The Beginner's Guide to Exosome RNA-Seq
Exosomes are small extracellular vesicles that contain RNA, proteins, and lipids. These vesicles play a crucial role in intercellular communication and have been implicated in various physiological and pathological processes. Exosome RNA-Seq is a powerful technique that can be used to study the RNA content of exosomes and gain insight into their function and regulation. In this guide, we will ...
By CD Genomics
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Overview of Microbial Epigenetics
Introduction to Microbial Epigenetics Epigenetics has been defined as the study of stable alterations in gene expression potentials that arise during development and cell proliferation, or alterations in DNA function without alterations in DNA sequence. Modern epigenetic features refer to the alteration of DNA and/or associated proteins without nucleotide sequence variance, which transmits the ...
By CD Genomics
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Exploring the Intricate Link Between Bile Acids and Disease
Bile acids are synthesized in the liver from cholesterol as a raw material. As a natural "emulsifier", they can promote the dissolution, digestion and absorption of fats, fat-soluble vitamins, etc. Meanwhile, as an important signaling molecule, bile acids can activate the relevant receptors to maintain the homeostasis of hepatic glucose and lipid metabolism, and interact with gut bacteria to ...
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What Is Metabolomics?
Metabolism is the assembly of biochemical reactions in living organisms, the material basis for life maintenance of living organisms, and an important basis for the study of life activities. Metabolomics studies the endogenous metabolic activities of life under the influence of the internal and external environments, including the detection and analysis of metabolite types and quantities and ...
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CD Genomics Takes Genomic Research to New Heights with Ribo-seq Technology
CD Genomics, a well-established leader in transcriptome solutions, is pleased to announce the introduction of Ribosome Profiling technology. This innovative technique promises to provide valuable insights into gene expression, protein synthesis, and regulation, offering potential advancements in the field of RNA translation research. Ribo-seq is a cutting-edge high-resolution sequencing ...
By CD Genomics
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Nanopore Sequencing: Bioinformatics Analysis of ONT Data
Oxford Nanopore Technologies (ONT) sequencing has witnessed significant progress in recent years, becoming a key player in the genomics field. As the technology matures, so does the bioinformatics analysis of ONT data. Researchers have been diligently developing specialized tools and algorithms to better utilize the unique characteristics of ONT data, such as long read lengths and ionic current ...
By CD Genomics
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Cytokines: The Master Regulators of Immunity and Inflammation
Cytokines are a broad class of tiny proteins that are essential for controlling inflammation and immunological responses. Numerous cell types, including fibroblasts, endothelial cells, immunological cells, and epithelial cells, produce these signaling molecules. Serving as intermediaries, they synchronize various cell functions to elicit the body's defense mechanisms against infections, tissue ...
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The Role of Exosome RNA in Cancer
The Relationship Between Exosomes and Cancer Exosomes are nanoscale vesicles derived from intracellular lysosomes that shuttle a variety of biomolecules, such as nucleic acids, proteins, lipids, amino acids and metabolites, and play a key role in regulating intercellular communication. Exosomes can be secreted by almost all types of cells, including immune cells, blood cells, neuronal cells, ...
By CD Genomics
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Long-Read: Nanopore Full-Length Transcriptome Sequencing
Nanopore full-length transcriptome sequencing is an innovative technique that utilizes Oxford Nanopore Technologies' (ONT) sequencing platform to obtain comprehensive and uninterrupted high-quality full-length sequences of transcripts. This cutting-edge approach enables researchers to accurately identify various structural variations within transcripts, including alternative splicing, gene ...
By CD Genomics
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