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Disease Mechanisms Equipment & Supplies
17 equipment items found
Manufactured by:CN Bio based inCambridge, UNITED KINGDOM
NASH-in-a-box contains everything required to recreate our industry-validated human in vitro Non-alcoholic steatohepatitis (NASH) model in your own ...
by:Citus AG based inDübendorf, SWITZERLAND
We introduce a novel ultra-light suction device, NIMBLEeva, overcoming the limits of the existing instruments. The specific working principle enables a lightweight design, preventing interaction between the observer and the suction probe, and by this the measurement outcome significantly ...
Manufactured by:Keeton Industries, Inc. based inWellington, COLORADO (USA)
Increase Survival – Probiotics are proven to increase survival by reinforcing the body’s natural defense mechanisms, increasing disease resistance and suppressing potentially harmful ...
Manufactured by:OncoQR ML GmbH based inVienna, AUSTRIA
Cancer cells have the ability to escape our immune system´s defenses – by outsmarting checkpoint molecules on our immune cells. For more than three decades, science and industry have been working to overcome cancer’s tricky battle ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
FHD-609 is a PROTAC degrader and inhibitor of BRD9 (Bromodomain-containing protein 9). FHD-609 targets to ncBAF, can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment. (Blue: BRD9 ligand-6 (HY-49393), Black: linker (HY-168309); Pink: ...
Manufactured by:BioVariance GmbH based inKonnersreuther Str. 6g, GERMANY
We analyze your complex molecular biological and biomedical data using state-of-the-art procedures to identify their fundamental correlations across all biological levels – from DNA to RNA to Proteins and Metabolites. Applying Machine Learning, neuronal networks, mathematical algorithms and statistical methods, we analyze your data based on your specific question. Besides, automatization ...
Manufactured by:Gamma-Service Medical GmbH based inLeipzig, GERMANY
GSR C1 - Gamma irradiation of blood and blood derivatives, cell cultures, transplants for comfortable, effective and precise irradiation in transfusion medicine and research (3.8 liter irradiation ...
Manufactured by:HemoShear Therapeutics, Inc. based inCharlottesville, VIRGINIA (USA)
HST5040 is an investigational small molecule therapy being developed by HemoShear to reduce the levels of toxins associated with methylmalonic acidemia (MMA) and propionic acidemia (PA), rare genetic disorders caused by the de?ciency of certain enzymes required to metabolize amino acids. HST5040 is formulated for convenient daily administration at home as a liquid taken either orally or through a ...
Manufactured by:Finch Therapeutics Group, Inc. based inSomerville, MASSACHUSETTS (USA)
In collaboration with Takeda Pharmaceuticals, we are developing FIN-524 and FIN-525, orally administered, Targeted Consortia product candidates designed for the treatment of ulcerative colitis (UC) and Crohn’s disease (CD), respectively. UC and CD are the two most common types of IBD, an autoimmune condition that causes inflammation of the gastrointestinal (GI) ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
NX-13 is a first-in-class, orally active and gut-restricted agent that selectively targets and activates the NLRX1 pathway to induce immunometabolic changes. NX-13 results in lower inflammation and responses in inflammatory bowel disease. NX-13 can be used for the research of crohn's disease and ulcerative ...
Manufactured by:Siolta Therapeutics based inSan Carlos, CALIFORNIA (USA)
Siolta’s Precision Symbiotics Platform enables rapid LBP development. A platform focused on translating microbiome science into novel therapeutics for a healthier world. Siolta’s patient-centric platform leverages our internal expertise in microbiome data analysis, machine learning, anaerobic microbiology, and translational studies to rationally design and optimize multi-strain live ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
5-Heptadecylresorcinol (AR-C17), a phenolic lipid component, is also an orally active mitochondrial protector. 5-Heptadecylresorcinol improves mitochondrial function via sirtuin3 signaling pathway, thus alleviates endothelial cell damage and apoptosis. 5-Heptadecylresorcinol induces sirtuin3-mediated autophagy. 5-Heptadecylresorcinol reduces the atherosclerotic plaques in the aortic root region ...
Manufactured by:RayBiotech Life, Inc. based inPeachtree Corners, GEORGIA (US) (USA)
Semi-Quantitative, Sandwich-Based, Membrane Antibody Arrays. The RayBio® Membrane-Based Antibody Arrays (C-Series) are tools for screening and comparing expression levels of many cytokines, growth factors, proteases, soluble receptors, and other proteins in a wide variety of sample types. The C-Series Arrays utilize the sandwich immunoassay principle, wherein a panel of capture antibodies is ...
Manufactured by:DX Fluidics based inSuzhou, CHINA
Microfluidic chips are instrumental in advancing research in cell biology and medical science. These chips integrate microfluidics and cell biology to simulate and study cell cycles, molecular and biological processes. They utilize precise microstructures to manipulate and observe cells at a microscopic scale. Applications include drug screening, disease modeling, and tissue engineering. Various ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Griseofulvin is an orally active antifungal antibiotic with antitumor activity. Griseofulvin induces apoptosis and G2/M cell cycle arrest in cancer cells. Griseofulvin also has cardiovascular modulatory activity, reducing angina pectoris, relieving hand artery spasm associated with onychomycosis, and peripheral vascular diseases such as shoulder-hand ...