Hospital Analyses Equipment For Medical Diagnostics
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Manufactured by Novodiax, Inc.based in USA
Polymerized horseradish peroxidase (pHRP)-labeled anti-human Cytokeratin 8/18 (CK 8/18) antibody (Cytokeratin 8/18 pHRP) is intended for laboratory use to qualitatively identify by light microscopy the presence of CK 8/18 in sections of formalin-fixed, paraffin-embedded tissue sections or frozen tissues using immunohistochemistry (IHC) test methods. The clinical interpretation of any staining or ...
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Manufactured by Diatech Pharmacogenetics srlbased in ITALY
Detection of the main mutations of exon 2 (codons 12, 13), of exon 3 (codons 59, 61) and of exon 4 (codons 117, 146) of the gene KRAS using 8; oligo mixes. Each mix allows the co-amplification of one or more mutated alleles plus an endogenous control gene. A specific oligo control mix enables; the evaluation of the quality and the quantity of the DNA in each ...
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Manufactured by Amoy Diagnostics Co., Ltd.based in CHINA
The phosphoinositide-3 -kinase catalytic alpha (PIK3CA) gene produces the p110 alpha (pl 10a) protein, which is one subunit of an enzyme called phosphatidylinositol 3-kinase (PI3K). PI3K plays a key role ofPI3K/Akt signaling pathway in numerous cellular processes critical for cancer progression, including metabolism, growth, survival, and motility. Somatic mutations in the PIK3CA gene are found ...
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Manufactured by Amoy Diagnostics Co., Ltd.based in CHINA
Lung cancer is one of the most common malignant tumor, and 80~85% of lung cancers are non-small cell lung cancer (NSCLC). There are many driver mutations in NSCLC. The frequency of mutations in patients with NSCLC for the EGFR gene is 10~35%, for KRAS 15?25%, for BRAF1-4%, for NRAS is 1%, for HER2 2-4%, and for PIK3CA 1-3%. About 3-7% of NSCLC patients have gene fusion in ALK, 2% in ROS1, and 1% ...
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Manufactured by Precision For Medicine, Inc.based in USA
Extensive inventory of pathologist-reviewed formalin-fixed paraffin-embedded tissue blocks & slides from normal and diseased subjects. ...
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Manufactured by Oxford Gene Technology IP Limitedbased in UNITED KINGDOM
The HER2 amplification probe consists of a 347kb probe labelled in red, spanning the HER2 (ERBB2) gene and neighbouring regions, and a green probe for the chromosome 17 ...
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Manufactured by Amoy Diagnostics Co., Ltd.based in CHINA
The Homologous Recombination Repair (HRR) pathway plays an important role in the repair of double-strand breaks, which is a major cause of cancer development. It has been demonstrated that loss of function of HRR genes, Homologous Recombination Deficiency (HRD) is the inability to repair double strand breaks and will cause a higher risk of developing cancer[1-5]. Patients with HRD showed higher ...
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Manufactured by Veracyte, Inc.based in USA
Using prognostic information to inform next steps in patient care. The Prosigna Breast Cancer Prognostic Gene Signature Assay uses advanced genomic technology to inform next steps for patients with early-stage breast cancer, based on the genomic make-up of their disease. The test analyzes the activity of 50 genes known as the PAM50 gene signature, along with clinical-pathological features, and ...
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Manufactured by Bioceptbased in USA
Biocept’s Target Selector™ molecular assay kits detect key oncogene mutations through the analysis of both Formalin-Fixed Paraffin-Embedded (FFPE) tissue gained from surgical biopsies as well as circulating tumor DNA (ctDNA) gained from blood-based liquid biopsies. The EGFR pathway can include mutations that are among the most frequently evaluated biomarkers for lung ...
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based in USA
Predicting Individual Risk of Metastasis: DecisionDx-SCC is now commercially available. DecisionDx-SCC is clinically validated as a significant predictor of metastasis and the strongest predictor of risk compared to traditional clinical and pathological factors. DecisionDx-SCC complements traditional prognostic risk assessment factors, enabling more informed choices about treatment and follow-up ...
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Manufactured by Novodiax, Inc.based in USA
Cluster of Differentiation 45 (CD45) pHRP Anti-Human Staining Kit immunohistochemistry (IHC) reagent is for use on frozen and formalin-fixed-paraffin-embedded tissues. The CD45 antigen is a protein which was originally called Leukocyte Common Antigen and recognizes an antigen found on lymphoid cells. Anti-CD45 antibody is a useful tool for identifying tumor cells of lymphoid origin. It is ...
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Manufactured by Diatech Pharmacogenetics srlbased in ITALY
Detection of the main mutations of codon 600 of the gene BRAF using 4 oligo mixes. Each mix allows the co-amplification of one or more mutated alleles plus an endogenous control gene. A specific oligo control mix enables the evaluation of the quality and the quantity of the DNA in each ...
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Manufactured by Novodiax, Inc.based in USA
Cluster of Differentiation 20 (CD20) is a polymerized horseradish peroxidase (pHRP)-labeled anti-CD20 (R272) rabbit monoclonal antibody intended for laboratory use using frozen or formalin-fixed-paraffin-embedded tissues. CD20 also known as B-lymphocyte antigen, is a membrane polypeptide protein that is present in a majority of B-cells in peripheral blood and lymphoid ...
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Manufactured by Amoy Diagnostics Co., Ltd.based in CHINA
Neurotrophic tropomyosin-related kinase (NTRK) is a group of high affinity nerve growth factor (NGF) receptors, including tropomyosin receptor kinases (Trk) A, B, and C which are encoded by NTRK1, NTRK2, and NTRK3 genes, respectively. NTRK proteins, upon NGF ligand binding, function in the phosphorylation of members of the RAS/MAPK, PI3K/AKT, PLC-y pathways that play a key role in cell ...
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based in USA
All fresh frozen tissue samples are collected under IRB approval by certified medical ...
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Manufactured by Panagene Inc.based in SOUTH KOREA
PANAMutyper™ EML4-ALK Screening Kit is the qualitative diagnostic test kit which is able to detect 16 different EML4-ALK fusion genes of tissue from non-small cell lung cancer (NSCLC) patients using peptide nucleic acid (PNA) probes in a real-time PCR system. The PANAMutyper™ EML4-ALK Screening Kit is intended as an aid for screening EML4-ALK fusion-positive NSCLC patients who would ...
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Manufactured by Amoy Diagnostics Co., Ltd.based in CHINA
The AmoyDx BRCA1 and BRCA2 Gene Mutation Detection Kit (Reversible Terminator Sequencing) is intended for qualitative detection of BRCA1 and BRCA2 variants using DNA isolated from peripheral whole blood, fresh-frozen tissue or formalin-fixed paraffin-embedded (FFPE) tissue samples. The kit provides full and uniform coverage of both BRCA1 and BRCA2 genes, covering all coding exons, exon/intron ...
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Manufactured by Amoy Diagnostics Co., Ltd.based in CHINA
The Homologous Recombination Repair (HRR) pathway plays an important role in double strand break, which is the major cause of cancer development. It has been demonstrated that loss of function of HRR genes (e.g. BRCA1, BRCA2, PALB2) and homologous recombination deficiency (HRD) will cause a higher risk of developing cancer, and patients with HRR gene mutations showed higher response to PARPi and ...
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Manufactured by HTG Molecular Diagnostics, Inc.based in USA
The HTG EdgeSeq processor, assays, and parser software facilitate analysis of gene expression profiles from a wide variety of specimen types to accelerate discovery, support translational applications and evaluate target biomarkers for companion diagnostics. Our extraction-free specimen preparation and quantitative nuclease protection chemistry assays automate preparation of mRNA and miRNA ...
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Manufactured by NanoStringbased in USA
The nCounter Low RNA Input Kit enables the generation of high-quality gene expression profiling of up to 800 gene targets from as little as 1 ng of sample. The kit is optimized for use with RNA from Formalin-Fixed Paraffin-Embedded (FFPE) tissue as well as crude cell lysates. The streamlined, user friendly workflow enables gene expression studies from small samples amounts and reliable detection ...
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