Medical Biomarkers Downloads
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IVDR: our next Challenge? - Brochure
With the EU In Vitro Diagnostic Medical Devices Regulation (IVDR) becoming applicable in May 2022, the European Bioanalysis Forum, as many others, is looking at the impact of this regulation on (bio)pharmaceutical drug research and development. Already, we observe a growing concern of the industry on potential scope creep of the IVDR into early clinical studies for assets where it is believed the ...
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Lumigen - Model AGP-SP-2 - Heavily Glycosylated Protein - Brochure
Alpha-1-acid glycoprotein (AGP) is a heavily glycosylated protein that is expressed in the liver and secreted into blood. It is a positive acute phase reactant; liver expression and serum concentrations increase as a result of injury, infection or disease. In studies at Life Diagnostics, Inc. we found that serum AGP levels increased approximately 25-fold twenty-four hours after rats were ...
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Untargeted Metabolomics Strategy VS Targeted Metabolomics Strategy
Targeted and non-targeted metabolomics take part in food identification, disease research, animal model verification, biomarker discovery, disease diagnosis, drug development, drug screening, drug evaluation, clinical research, plant metabolism research, and microbial metabolism research. ...
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Q-Plex - Model 111049MS - Mouse Cytokine Inflammation HS (14-Plex) - Brochure
The Q-Plex Mouse Cytokine Inflammation HS (14-Plex) is a fully quantitative ELISA-based chemiluminescent assay allowing the concurrent measurement of 14 biomarkers or analytes. Using just 25 µL of sample per well, up to 80 samples can be assayed for all 14 markers in the panel within 5.5 hours. The Q-Plex Mouse Cytokine Inflammation HS (14-Plex) provides researchers an easy to use and ...
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Q-Plex - Model 112149MS - Mouse Cytokine Screen HS Stripwells (16-Plex) - Datasheet
The Q-Plex™ Mouse Cytokine HS Stripwells (16-Plex) is a fully quantitative ELISA-based chemiluminescent assay allowing the concurrent measurement of sixteen biomarkers or analytes: GMCSF, IFNγ, IL-1α, IL-1β, IL-2, IL-3, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17a, MCP-1, MIP-1α, RANTES, and TNFα. Each kit contains a 96-well plate, featuring the relevant biomarker ...
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Thermophilic Fucosidase - Datasheet
This product is a recombinant a-L-fucosidase (glycosyl hydrolase family GH29, EC #3.2.1.51) cloned from Thermotoga maritima, a hyperthermophilic bacterium, and expressed in Escherichia coli with an N-terminal 8xHis-tag. The 8xHis tag may be removed by digestion with FasTEVTM (Cat #GE0501), a TEV protease with enhanced stability and catalytic activity. ...
By Lectenz Bio
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Optimum - S Acetyl Glutathione (Superior Oral Activity) - Brochure
S-Acetyl Glutathione is an acetylated form of glutathione. This form is well-absorbed and more stable throughout the digestive tract than other forms on the market. Use of stomach acid-resistant capsules further protect stability. Laboratory data showed that S-acetyl glutathione increased intracellular glutathione and had a positive effect on many oxidative stress biomarkers.* ...
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Dedicated to Creating Better Treatments for Cancer - Datasheet
LIXTE BIOTECHNOLOGY HOLDINGS, INC. is a clinical-stage drug discovery company using biomarker technology to identify enzyme targets associated with cancer to design novel compounds to attack those ...
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Pinaka - Model 360 - Theranostic Profiling Technology for Circulating Tumor Cells - Brochure
Pinaka™ is an advanced non-invasive blood test which provides therapeutically relevant information via a safe, simple and quick blood draw. Pinaka™ evaluates blood sample to detect ‘Circulating Tumor Cells’ (CTCs), which are cancer cells that escape from the tumor and enter the blood stream. Pinaka™ enriches these CTCs from the blood sample and confirms their ...
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CorInsights - Model MRI - Advanced Reporting Tool - Brochure
Integrated. Extensive. Relevant. ADMdx offers diagnostic tools that enable an integrated, insightful view of the effects of disease to support medical professionals in patient care. Our full spectrum CRO services for CNS imaging trials use a variety of PET and MRI biomarkers that enable us to provide early, reliable information for decision-making and clinical trial ...
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About CanAssist Breast Test and Validation Map - Brochure
CanAssist Breast is a prognostic test that offers vital insights to help oncologists determine the optimal treatment regimen for each patient. This innovative test provides information about risk of cancer recurrence that is otherwise unavailable from conventional clinical parameters. CanAssist Breast looks at critical biomarkers in the tumour to determine whether a patient is "low-risk" or ...
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Lipidomics Research Methods at Creative Proteomics
Untargeted lipidomics allows the isolation and identification of all lipid compounds and their metabolites in biological samples to screen for biomarkers, suitable for a wide range of complex biological samples. A single assay can provide overall comprehensive lipidomic information. ...
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Hunt for miRNA Signatures in Cancer - A Case Study of Sequencing and Bioinformatics
Sequencing technology has advanced successfully to become one of the most used routine tools for life science research. Not only can it provide a wealth of valuable information, but when combined with other research methods, sequencing can also supply massive information. Sometimes, even with just sequencing and biomarker analysis alone, scientists can also discover biomarkers in cancer. ...
By CD Genomics
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Quark - Model NextAmp - Analysis System- Brochure
A gene chip based diagnostic platform designed to analyze up to 100 biomarkers in under two hours, with minimal hands on time. ...
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Mediagnost - Model E35 - Acid-Labile Subunit (ALS) ELISA Datasheet
The acid-labile subunit (ALS) consists of 577 amino acids and is part of the ternay complex of the Insulin-like growth factor (IGF) -system. The ternary complex consists of IGF-I/ IGFBP-3 or IGFBP-5 and the ALS, within the complex the half-life of IGF-I is singnificantly prolonged, it increases from 30 -90 minutes up to 12 hours. Thus, the complex is one means to regulate the bioavailablity of ...
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Mediagnost - Model E09 - Adiponectin ELISA Datasheet
Adiponectin is a protein of 30kDa which exists in several multimeric forms. About 0,01% of the proteins in human serum are adiponectin. The ADIPOQ-Gen is the gene mostly expressed by adipocytes. In spite of that the serum adiponectin concentration is negatively correlated with body fat mass. The protein consists of 244 amino acids and has a globulary domain which shows similarity to TNF alpha. ...
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Mediagnost - Model E024 - Growth Hormone Binding Protein (GHBP) ELISA Datasheet
Growth Hormone Binding Protein (GHBP) consists of 238 amino acids and includes four sides for glycosylation and three disulfid bounds. In humans GHBP is formed by receptor shedding of the growth hormone receptor by a metalloprotease (ADAM17). Regulation of biological availability of GH is possibly the physiologic role of of GHBP. Thus, the half-life of GH is prolonged up to 100 minutes by binding ...
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SeraCare Seraseq - Whole Transcriptome RNA Seq Mix Datasheet
Whole transcriptome RNA sequencing allows for the analysis of fusion genes with potential clinical utility that currently cannot be detected using the limited genomic coverage of targeted NGS panels. Additionally, some clinical cancer testing labs are evaluating whole transcriptome panels for improved diagnostic yields and clinical utilization for NGS-based tumor profiling test reimbursements. ...
By LGC SeraCare
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Enzymes for Producing Homocysteine Assay Kit
Elevated plasma homocysteine concentration is a clinical biomarker for increased risk of cardiovascular disease, ischemic stroke, and myocardial infarction. Homocysteinylated proteins may also act as autoantigens, triggering arterial inflammation and atherosclerosis. ...
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