Molecular Diagnostics Applications
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Tissue Homogenizers – Sample preparation for Cancer research
Hard tissues such as those from tumors can be particularly difficult to homogenize, and animal models are often used in cancer research. Precellys homogenizer is perfectly adapted to applications of this ...
By Bertin Technologies based in Montigny-le-Bretonneux, FRANCE.
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Medical solutions for vaccine platform sector
2A Pharma’s vaccine platform is based on mutated parvoviral particles consisting essentially of one protein. The particles contain no viral genome and are replicative defective and non-pathogenic. The particle capsid surface has repetitive, immunogenic sites, where peptides of interest can be inserted and allows us to generate monovalent or bivalent vaccines as required. Each peptide of interest will be presented 60 times on the capsid surface and both the innate and adaptive immune systems are activated to ...
By 2A Pharma ApS based in Aalborg Øst, DENMARK.
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Researchers - FIRE—Blazing a New Trail in Guided Surgery and Diagnostics
Cancer-targeted molecular probes have the potential to revolutionize surgery and diagnostics. Offering unparalleled flexibility and outstanding performance, FIRE epitomizes the cutting edge of this technology. FIRE’s quenched, substrate-based probe (qSBP) technology guides surgeons by ensuring probe signal is only seen when cancer is detected, clearly delineating tumor tissue from healthy tissue and virtually eliminating spurious background fluorescence common in other probes. ...
By Akrotome Imaging, Inc. based in Cleveland, OHIO (USA).
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Gene Synthesis Based on htDNA-chip®
Gene synthesis refers to the artificial synthesis of double-stranded DNA molecules in vitro. At present, the required target DNA fragments are mainly obtained and amplified through gene cloning. Gene cloning is a revolutionary research technology, which can be summarized as: dividing, cutting, connecting, transferring, and selecting. The ultimate goal is to introduce the target gene into the host cell through corresponding technical means, and the target gene is replicated in large numbers in the host cell. ...
By CD Biosciences - htDNA-chip® based in Shirley, NEW YORK (USA).
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Rapid Allergy Testing for Allergic Rhinitis & Allergic Asthma Tests
Nearly 35% of respiratory allergy sufferers experience both allergic rhinitis and asthma, which impact their quality of life 1,2. Standard diagnostic methods such as skin tests are at times impossible or difficult to perform, have limited reliability and must be performed by trained Allergy and Asthma Specialists. Similarly, laboratory blood tests for specific immunoglobulin E (sIgE) levels have a long turnaround time until results, thus delaying treatment up to several days and requiring multiple visits. Fast and ...
By Abionic SA based in Epalinges, SWITZERLAND.
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Software Solutions for Deep Mutational Scanning & Selection
Cyrus’s protein biochemistry capabilities include advanced selection methodologies in both yeast and mammalian cell systems. These tools can interrogate large numbers of mutations in cell surface receptors and many globular proteins, offering a unique path forward for protein optimization based on high quality, physiologically-relevant data in eukaryotic or – specifically – human ...
By Cyrus Biotechnology Inc. based in Seattle, WASHINGTON (USA).
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Bioinformatics software solutions for variant detection sector
Whole genome, exome, or targeted panel DNA sequencing (DNA-Seq) studies can identify genetic variants that contribute to disease and phenotypes. Partek offers powerful and easy-to-use tools for processing and analyzing your DNA sequencing data. With the latest databases and bioinformatics tools available in a point-and-click interface, variant analysis is simple. ...
By Partek Incorporated based in Chesterfield, MISSOURI (USA).
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Proteome array screening solutions for protein - nucleic acid interactions sector
Identify interacting proteins for your DNA/RNA molecule of interest. Profiling of nucleic acid binding on HuProt human proteome microarrays can reveal interactions with the largest collection of individual human proteins available on a single slide. Nucleic acid-protein interactions regulate many aspects of gene expression and thus cell physiology and pathology. DNA-protein interactions occur via a range of binding motifs present in transcription factors and nuclear receptors (e.g. DNA-binding domains, zinc ...
By Cambridge Protein Arrays Ltd. (CPAP) based in Cambridge, UNITED KINGDOM.
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FluidFM Nanoprinting - Print any pattern at sub-micrometer resolution
FluidFM® Nanoprinting for researchers who need precise tools to manipulate, create and prototype on the nano- and microscale. FluidFM technology with its microfluidic probes offers unprecedented versatility and control to print patterns and explore nanostructure creation. Whether you are working with protein arrays for sensing applications, chemical gradients for cell migration studies, want to understand chemical processes in femtoliter droplets, or are interested to develop the next generation of ...
By Cytosurge AG based in Glattbrugg, SWITZERLAND.
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Medical solutions for molecular diagnostics sector
In your environment - in your home - at the clinic. Current Testing is Failing the Modern World. Low-plex: Many types of tests are required to diagnose disease today. Centralized: Centralized testing is slow and complex and remains a barrier to connected health. Limited Access: Lack of access propagates disease in the community: Cost and testing are fundamental ...
By Roswell Biotechnologies Inc based in San Diego, CALIFORNIA (USA).
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UV Technology for Healthcare
According to the latest guideline on the diagnosis and treatment of the novel coronavirus released by the National Health Commission, the virus is sensitive to ultraviolet light and heat, so ultraviolet radiation can effectively eliminate the virus. Radiant manufactures UV machines that could be repurposed to sterilize PPE for public safety and healthcare workers during the pandemic. The machine use high-intensity ultraviolet light to damage the DNA of bacteria and viruses that may be living on surfaces such as ...
By Radiant Industrial Solutions based in Houston, TEXAS (USA).
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Liquid Biopsy Solutions for Gastric Cancer
You need a complete answer to provide the best ...
By Biocept based in San Diego, CALIFORNIA (USA).
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Single-cell omics with Live-seq
Introducing single-cell biopsy The novel non-invasive method for single-cell omics The novel method that keeps your cells alive during biopsy from single cells Single-cell omics addresses cellular heterogeneity head on by isolating and analyzing molecular components from individual cells. While many of the existing technologies rely on cell lysis — single-cell biopsy is the only non-invasive single-cell analysis method that allows researchers to take transcriptome snapshots of a ...
By Cytosurge AG based in Glattbrugg, SWITZERLAND.
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Diagnostic Solutions for Lung Cancer
Non-small cell lung cancer (NSCLC) is not a single disease, but a collection of cancer types whose pathology is classified by histology (cells) and molecular profiling (genetic and protein ...
By Biocept based in San Diego, CALIFORNIA (USA).
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ctDNA
SNAQ-SEQ ctDNA spike-in standards Liquid biopsies offer the promise of earlier detection and monitoring of cancer patients’ treatment progression. However, as applications increasingly rely on ultra low variant allele frequency detection, NGS-based assays are beset with significantly more noise below 0.5% VAF that increases the rate of false positives. Laboratories looking to implement ctDNA assays need better quality controls that can ensure accurate detection and reporting by variant calling ...
By AccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA).
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Radioisotopes for Therapeutic Radiopharmaceuticals
NorthStar Medical Radioisotopes is poised to become the first-in-class supply chain for the future of therapeutic radiopharmaceuticals. Check back for progress on our non-carrier-added (n.c.a) Ac-225 and Cu-67 development ...
By NorthStar Medical Radioisotopes, LLC based in Beloit, WISCONSIN (USA).
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DNA-based Medical Beauty Based on htDNA-chip®
With the development of society, people are becoming more and more concerned about appearance and body type. The medical beauty industry came into being and developed rapidly. The application of DNA technology in the medical beauty industry is becoming more and more common. Firstly, genetic testing related to skin conditions and obesity is more and more popular. According to the test results, the obesity type and skin condition can be known clearly, and the appearance and body shape problems can be solved in a ...
By CD Biosciences - htDNA-chip® based in Shirley, NEW YORK (USA).
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SARS-CoV-2 Targeted Sequence Analysis with SRSLY
This application note describes the utility of SRSLY in performing targeted sequence analysis of SAR-CoV-2 RNA-Seq libraries were generated with SRSLY within 3 hours. Subsequent enrichment of viral sequences can be performed with a user-preferred hybridization-based panel. ...
By Claret Bioscience based in Santa Cruz, CALIFORNIA (USA).
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Target Enrichment with SRSLY and Twist Exome Panel
SRSLY NGS library preparation with twist exome panel enrichment for ctDNA SNP profiling. Cell-free DNA (cfDNA), found circulating in blood, originates predominantly from dying cells. In healthy individuals the vast majority of cfDNA derives from hematopoietic myeloid and lymph cells undergoing apoptosis. However, in individuals with cancer, a variable fraction of the cfDNA derives from tumor cells undergoing apoptosis and/or necrosis. This tumor derived fraction of cfDNA is known as circulating tumor DNA (ctDNA). ...
By Claret Bioscience based in Santa Cruz, CALIFORNIA (USA).
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SRSLY Stringent Size Selection with Clarefy DNA Purification Beads
ClaretBio’s Clarefy Purification beads are the ultimate choice for retaining short DNA fragments. But we understand labs may have their own purification beads. We’ve put together a handy comparison how to still get the best SRSLY NGS libraries with other, 3rd party ...
By Claret Bioscience based in Santa Cruz, CALIFORNIA (USA).
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