Urine Analyses Articles
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Significance of Diagnostic Enzyme Detection
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
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Organic Acids Analysis
The organism undergoes thousands of biochemical reactions every moment to maintain our growth, development and energy metabolism. Under normal circumstances, these biochemical reactions proceed smoothly step by step through various cycles or certain steps. The process by which the body changes carbohydrates, amino acids, and fats from nutrients to absorbable substances and wastes is called the ...
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What is Urine Flow Rate Test?
What is urine flow rate test? You may be unfamiliar with the term urine flow rate or urinary flow rate, which is a common medical term in urology. Put it simply, the rate of urine flow measures how fast urine flows, how much it flows out, and how long it takes. It is expressed in ml/s. Urine flow rate test is done mainly when the following symptoms appear: bladder residual urine increase ...
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Nanostics Announces the Launch of its Bladder Cancer Clinical Study Identifying Disease Predictors for Early Detection of Bladder Cancer
Clinical study launched in June 2022 with patient recruitment in Alberta with plans to expand to further sites across North America. The aim of the study is to validate a novel and minimally invasive liquid biopsy test for bladder cancer diagnosis using Nanostics’ ClarityDX® diagnostic platform. The study is supported in part by the Alberta Innovates AICE-Concepts Program with a ...
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Everything You Want to Know About Horseradish Peroxidase
Peroxidase, usually derived from horseradish, is a common enzyme used in clinical testing reagents. It is widely used not only in several biochemical assays but also in immunoassay (ELISA) kits. As a key component of the color development system of several kits, peroxidase has an important impact on the quality of the kits. Horseradish peroxidase (HRP) is the most commonly used enzyme because ...
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Validation of a two-gene mRNA urine test for detection of high-grade prostate cancer in German men.
Organizations Martini-Klinik Prostate Cancer Center and Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, MDxHealth, B.V., Nijmegen, Netherlands, MDxHealth, Inc., Irvine, CA, Mathematical Modeling, Statistics and Bioinformatics, Ghent University, Ghent, Belgium, Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany Abstract ...
By MDxHealth
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Huateng Pharma Supplies Canagliflozin Intermediates With Commercial Scale Production
Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...
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What Are the Applications of Enzymes in Disease Research and Treatment?
With the development of biotechnology in the modern information age, the research, development and utilization of enzymes have become more and more in-depth, and correspondingly, the application of enzymes in medicine has become more and more extensive. 1. The relationship between enzymes and certain diseases The diseases caused by the lack of enzymes in the human body are mostly congenital or ...
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Monlab SL uses iPeak+ to obtain rapid results in drug testing
Monlab SL is a company dedicated to the service of the clinical diagnostic laboratory. They are providing a service according to the needs of hospitals, faculties, research centers, and clinical analysis. One of their business units is the marketing of reliable individual and multipanel blood and urine lateral flow tests. Monlab SL was looking for a reader that would analyze their lateral flow ...
By IUL S.A.
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Detailed Introduction to Steroids Analysis
Steroid hormone is a class of compounds that contain cyclopentane polyhydrophenanthrene structure formed by cholesterol and catalyzed by cytochrome P450 enzymes. Steroid hormones mainly include adrenocorticotropic hormones secreted by the adrenal cortex and sex hormones secreted by the gonads, which are mainly divided into four categories: progesterone, corticosteroid, estrogen and androgen. ...
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Biochemical and Clinical Applications of Glucose Oxidase (GOD)
Glucose oxidase (GOD) is a typical oxidoreductase found in honey and molds such as Penicillium notatum. It can highly specifically catalyze the β-D-glucose reaction to generate gluconic acid, which has the function of converting glucose and removing oxygen. Since GOD can quantitatively generate hydrogen peroxide, it is widely used in the field of biochemistry and clinical examination as a ...
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A translational study of Galectin-3 as an early biomarker and potential therapeutic target for ischemic-reperfusion induced acute kidney injury
Abstract Purpose: We evaluated Galectin-3 (Gal-3) as a potential early biomarker of acute kidney disease (AKI), and the effect of Gal-3 inhibition by modified citrus pectin (P-MCP) on renal ischemia/reperfusion (I/R) induced AKI. Methods: Among fifty-two post-cardiac surgery patients, serum and urine Gal-3 levels were examined on intensive care unit (ICU) admission. In a rat renal I/R ...
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Application of Enzyme Detection in Clinical Diagnosis
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
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Timing of urinary estrone-3-glucuronide tests
Background The onset of a woman's fertile phase can be identified by an increase in concentration of urinary metabolites of estradiol, including E1-3G (estrone-3-glucuronide). Home ovulation tests typically detect the lutenising hormone (LH) surge, which identifies the day before and day of ovulation. Some tests also measure E1-3G to identify the user's wider fertile phase. Such tests ...
By Clearblue
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hCG and FSH Levels During Early Pregnancy and Reproductive Aging
Low levels of hCG are known to be co-produced with FSH during reproductive aging (during peri-menopause and menopause). A missed period could be indicative of pregnancy or peri-menopause for woman in later reproductive life, so understanding the reference ranges for hCG is important. Introduction hCG assays have high sensitivity and specificity for pregnancy1 Low levels of hCG are known to ...
By Clearblue
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Investigation on microbial inactivation and urea decomposition in human urine during thermal storage
The World Health Organization suggests storing human urine for at least 6 months at 20 °C prior to application as fertilizer to reduce the potential health risks from pathogenic organisms. Such a storage condition for human urine, however, not only requires a long period of time and large space but also ignores the risk of nitrogen losses. In this study, human urine underwent thermal ...
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Fertilizer from dried human urine added to ash and lime – a potential product from eco-sanitation system
This research explored the possibility of making fertilizer at a laboratory from source separated and untreated human urine added to ash and lime by drying at low temperatures. A mixture of ash and lime (1:1) was used as drying agent and human urine was applied as undiluted and fresh. Ash and lime were chosen as drying agents for maintaining a pH > 10 during the drying process, which ...
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An investigation into the potential use of nutrients recovered from urine diversion on a summer housing site: self-sufficiency based on nitrogen balance
ECOSAN is a recent domestic wastewater management concept which suggests segregation at the source. One of these streams, yellow water (human urine) has the potential to be used as fertilizer, directly or indirectly, because of its rich content of plant nutrients. One physicochemical method for indirect use is adsorption/ion exchange using clinoptilolite. This paper aims to present the ...
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Urine metabolomics of women from small villages exposed to high environmental cadmium levels
This study aimed to identify urine metabolites in women exposed to high cadmium levels. 21 women exposed to environmental Cd and 12 age‐matched controls were categorized as high (Urine Cd ≥ 15 µg/g creatinine [Cr]) (n = 9) or low (15 µg/g Cr > UCd > 5 µg/g Cr) (n = 12) exposure. Low molecular weight metabolites in urine were analyzed by gas chromatography and mass spectrometry after ...
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Technical Hints and Tips for Optimal Performance of your Loeser Osmometer
General function and description: The sample (serum, blood, urine or any other aqueous solution) is filled in a plastic sample tube and cooled via a Peltier element. These are semiconductor devices, which become cold on one side and warm on the other when electrical current flows through. The cold side cools the sample whilst the heat from the warm side dissipates into the air by convection. ...
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