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Medical Diagnostics Equipment & Supplies Near Usa West Virginia

155 equipment items found

MedChemExpress - Model Tamoxifen - 10540-29-1

MedChemExpress - Model Tamoxifen - 10540-29-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg ...
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MedChemExpress - Model DAPT - 208255-80-5

MedChemExpress - Model DAPT - 208255-80-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease ...
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MedChemExpress - Model Artesunate - 88495-63-0

MedChemExpress - Model Artesunate - 88495-63-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Artesunate is an inhibitor of both STAT-3 and exported protein 1 ...
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MedChemExpress - Model Tamoxifen Citrate - 54965-24-1

MedChemExpress - Model Tamoxifen Citrate - 54965-24-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious ...
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MedChemExpress - Model Minoxidil sulfate - 83701-22-8

MedChemExpress - Model Minoxidil sulfate - 83701-22-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in ...
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MedChemExpress - Model Sorafenib Tosylate - 475207-59-1

MedChemExpress - Model Sorafenib Tosylate - 475207-59-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Sorafenib Tosylate (Bay 43-9006 Tosylate) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. SorafenibTosylate is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib Tosylate induces autophagy and apoptosis. Sorafenib Tosylate has anti-tumor activity. ...
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MedChemExpress - Model Honokiol - 35354-74-6

MedChemExpress - Model Honokiol - 35354-74-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain ...
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MedChemExpress - Model WS6 - 1421227-53-3

MedChemExpress - Model WS6 - 1421227-53-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
WS6 is an IkB kinase and EBP1 inhibitor, with IC50 values of 0.24 nM, 0.21 nM, and 40.48 nM in MV4-11, MOLM13, and K562 cells, respectively. WS6 promotes the proliferation of alpha and beta cells in the pancreas, has antioxidant and anti-inflammatory activities, and can alleviate depression like behavior in ...
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MedChemExpress - Model Ginsenoside Rb2 - 11021-13-9

MedChemExpress - Model Ginsenoside Rb2 - 11021-13-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ginsenoside Rb2 is one of the main bioactive components of ginseng extracts. Rb2 can upregulate GPR120 gene expression. Ginsenoside Rb2 has antiviral ...
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MedChemExpress - Model Tolfenamic Acid - 13710-19-5

MedChemExpress - Model Tolfenamic Acid - 13710-19-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on ...
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MedChemExpress - Model Fasudil - 103745-39-7

MedChemExpress - Model Fasudil - 103745-39-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Fasudil (HA-1077; AT877) is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA, PKC, PKG, respectively. Fasudil is also a potent Ca2+ channel antagonist and ...
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MedChemExpress - Model Bazedoxifene hydrochloride - 198480-56-7

MedChemExpress - Model Bazedoxifene hydrochloride - 198480-56-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Bazedoxifene hydrochloride (TSE-424 hydrochloride) is an oral active, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene hydrochloride can be used for the research of osteoporosis. Bazedoxifene hydrochloride acts as an inhibitor of IL-6/GP130 protein-protein interactions. Bazedoxifene hydrochloride can ...
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MedChemExpress - Model Pitavastatin sodium - 574705-92-3

MedChemExpress - Model Pitavastatin sodium - 574705-92-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Pitavastatin (NK-104) sodium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin sodium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin sodium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin sodium also possesses anti-atherosclerotic, anti-asthmatic, ...
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MedChemExpress - Model Nutlin-3a - 675576-98-4

MedChemExpress - Model Nutlin-3a - 675576-98-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53?interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53?wild-type ovarian ...
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MedChemExpress - Model Compound C108 - 15533-09-2

MedChemExpress - Model Compound C108 - 15533-09-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell ...
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MedChemExpress - Model Dasminapant - 1570231-89-8

MedChemExpress - Model Dasminapant - 1570231-89-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Dasminapant (APG-1387), a bivalent SMAC mimetic and an IAP antagonist, blocks the activity of IAPs family proteins (XIAP, cIAP-1, cIAP-2, and ML-IAP). Dasminapant induces degradation of cIAP-1 and XIAP proteins, as well as caspase-3 activation and PARP cleavage, which leads to apoptosis. Dasminapant can be used for the research of hepatocellular carcinoma, ovarian cancer, and nasopharyngeal ...
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MedChemExpress - Model Altiratinib - 1345847-93-9

MedChemExpress - Model Altiratinib - 1345847-93-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Altiratinib (DCC-2701) is a multi-targeted kinase inhibitor with IC50s of 2.7, 8, 9.2, 9.3, 0.85, 4.6, 0.83 nM for MET, TIE2, VEGFR2, FLT3, Trk1, Trk2, and Trk3 ...
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MedChemExpress - Model UMI-77 - 518303-20-3

MedChemExpress - Model UMI-77 - 518303-20-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
UMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 μM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 ...
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Model Fiv Antibodies - Rapid Test

Model Fiv Antibodies - Rapid Test

Manufactured by:Fassisi, Gesellschaft fur Veterinardiagnostik und Umweltanalysen mbH   based inGoettingen, GERMANY
The rapid test to detect fiv antibodies in blood of cats: Can be used directly at any place, with results available within a few minutes, Economical screening test for serum, plasma and wholeblood, Easy on-site usage, All items required are included in the testkit, Storage at 15-30 degrees, FIV: sensitivity 91,67%, specificity ...
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Model ALZ-201 - Monoclonal Antibody for the Toxic Aß Oligomers

Model ALZ-201 - Monoclonal Antibody for the Toxic Aß Oligomers

Manufactured by:Alzinova AB   based inMölndal, SWEDEN
ALZ-201 is a monoclonal antibody that is specific for the toxic Aβ oligomers. ALZ 201 is currently in early preclinical ...
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