Medical Drugs Articles | Medical XPRT

What is GMP?

Hundreds of millions of Americans rely on life-saving and sustaining medications and medical devices every day. Ensuring the drugs and devices that they depend on are not contaminated is critical for the health of the country, and the responsibility of the U.S. Food and Drug Administration (FDA). To address safety concerns in the medical, pharmaceutical, and food industries, the FDA ...

Jun. 1, 2021

By MadgeTech, Inc.

How Medical Studies are Changing the World

The coronavirus pandemic remains one of the top concerns within the United States. However, Johns Hopkins, and other research centers, are actively working to continue medical research in all divisions of medicine and health. Learn the ongoing studies at Johns Hopkins, what issues they are solving and how we can all make a difference. ...

May 11, 2021

By C&A Scientific

A Brief Guide to Federal GMPs for Dietary Supplements

Ensuring quality, safety, and integrity of the dietary supplements require nutraceutical companies to build a culture of quality and meet compliance with Federal GMPs. Thankfully, the development of advanced technologies has made quality management for nutraceuticals more straightforward than ever. With the increasing popularity of dietary supplements, the concern for quality and safety is also ...

Apr. 14, 2021

By Qualityze Inc

Developing a Robust in Vitro Intestinal Model for Preclinical Candidate Screening of GI Toxicity

Gastrointestinal (GI) issues are common side effects of many drugs. Anticipating such side effects before clinical trials is limited by a lack of effective models for evaluating preclinical candidates for their potential to cause diarrhea, nausea, and other gut-related side effects. With its RepliGut® in vitro human intestinal model, Altis Biosystems is developing a system that could help ...

Apr. 12, 2021

By Altis Biosystems

Novel, Smaller and More Powerful CTLA4 Inhibitors for the Treatment of Solid Tumors

Abstract Immune checkpoint inhibitors (ICIs) have obtained durable responses in many cancers, making it possible to foresee their potential in improving the health of cancer patients. However, immunotherapies are limited at the moment to a minority of patients and there is a need for a better understanding of the basic molecular mechanisms and functions of pivotal immune molecules. Immune ...

Apr. 1, 2021

By Atomwise Inc.

Accurately Recapitulating Environmental Niches in Vitro Models of the Intestine

Advanced microphysiological systems can replicate aspects of intestinal complexity, such as epithelium self-renewal by stem cells in in vitro crypts or the interactions of microbes and intestinal epithelium mediated by a mucus layer. Availability of such models is key to progress in compound screening, disease modeling, and microbiome research. Defining a Niche A niche is a multidimensional ...

Mar. 11, 2021

By Altis Biosystems

A Bispecific Single-Domain Antibody Boosts Autologous Vγ9Vδ2-T Cell Responses Toward CD1d in Chronic Lymphocytic Leukemia (Clinical Cancer Research)

Purpose:Although considerable progress has been made withautologous T cell–based therapy in B-cell malignancies, appli-cation in chronic lymphocytic leukemia (CLL) lags behind dueto disappointing response rates as well as substantial toxicitythat is of particular concern in the elderly CLL population.Vg9Vd2-T cells form a conserved T-cell subset with strongintrinsic immunotherapeutic ...

Jan. 13, 2021

By LAVA Therapeutics N.V.

Novel Tumor Bed Marking in Breast Cancer: Expanding Beyond Lumpectomy

VeraForm® placement to assist with localization and delivery of adjuvant radiation Historically, lumpectomies resulted in a scar immediately over the lumpectomy site, dictating delivery of adjuvant radiation on scar location, and frequently on the presence of a seroma. Currently, the question persists as to the optimal means to help direct the radiation oncologist to effectively deliver ...

Dec. 17, 2020

By Videra Surgical Inc.

How to Deal With Skin Irritation From a Dust Mite Allergy?

Is the dust in your home causing itchy skin? If yes, here’s everything you need to know about how to treat skin irritation from a dust mite allergy: More than 50 million Americans suffer from allergies each year. In fact, it’s one of the leading causes of chronic illness in the United States! Take hay fever, for example—it affects over 8% of all adults. Insect allergies are ...

Dec. 3, 2020

By Airfree

Intracranial Neoplasms: The Evolution of Radiotherapies

CURRENT STANDARD OF CARE FOR BRAIN TUMORS The current initial standard of care for aggressive brain tumors—whether they are primary brain tumors (ie, tumors that originate in the brain), or metastatic tumors from cancers that started outside of the brain—is resection. After surgery, a follow-up treatment, also referred to as adjuvant treatment, is often recommended to help eliminate ...

Dec. 1, 2020

By GT Medical Technologies, Inc.

Why Water Usage Data is Critical to the Biopharmaceutical Industry

Few sectors are as captive to water requirements and regulations as the biopharmaceutical industry. Water is a critical component in the manufacture of active pharmaceutical ingredients (APIs), life-saving drugs, vaccines, PPE, testing kits and many more products. To gain a clear picture, water for industrial use represents a significant part of global water demand and if nothing is done to ...

Sep. 4, 2020

By MECO Incorporated

It is possible for pharmaceutical quality to be the combination of Quality by Design (QbD) and current Good Manufacturing Practices (cGMP)?

The following is the summary of a noteworthy discussion from the 2019 GMP Academy Master Course – Particle Measuring Systems, Rome, Italy The first GMP Academy Master Course took place from November 26 – 28 at Particle Measuring Systems (PMS) in Italy. International experts met to share their knowledge and expertise of regulatory requirements and practical applications pertaining to ...

Feb. 25, 2020

By Particle Measuring Systems

Advancing Cancer Treatments with ALZET Osmotic Pumps

The research summarized in this whitepaper provides a number of examples of how ALZET® pumps offer a superior pre-clinical drug dosing option for the delivery of a wide array of anti-cancer agents, including small molecules, immunotherapies, radiotherapies, combination treatments, and novel drug entities. This whitepaper also explores how ALZET® pumps have been used to successfully test ...

Jan. 24, 2020

By Charles River

The Power of Outcome-Based Pricing

In February of 2019, CEOs and senior executives from seven major pharmaceutical companies met with the Senate Finance Committee about drug pricing. During that meeting, AstraZeneca CEO Pascal Soriot discussed how value-based agreements have the potential to transform how medicines are priced and reimbursed in the U.S., and in doing so, triggered a host of discussions across the industry on the ...

Dec. 12, 2019

By Vistex Inc

Biopharmaceuticals: Faster to full scale with simulation – Abec employs advanced simulation software from Siemens to help its customers scale up biopharmaceutical production

Medicine production starts in a lab, where cells are cultured and bacteria fermented in small batches. When it’s time to move to industrial-scale production, Abec – a supplier of bioreactors and fermenters – employs advanced simulation software from Siemens. Abec, a supplier of bioreactors and fermenters, employs advanced simulation software from Siemens ...

Dec. 9, 2019

By Siemens AG

Upgrades to Our Cancer Model Database - Case Study

We've added over 125 new datasets to our Cancer Model Database. It provides access to a comprehensive collection of well-established tumor models for early-stage oncology research and increases their translational capabilities to the clinic. The update adds new patient-derived xenograft (PDX) models for several cancer types, including anal, colon, kidney, renal, and leukemia. Additionally, this ...

Dec. 3, 2019

By Charles River

IMCAS Americas 2019 Shined in Sunny Cartagena

The third annual IMCAS Americas, held in Cartagena, Colombia in August, attracted a motivated crowd of more than 900 delegates from 30 countries who came to learn and network with colleagues and key opinion leaders. “The congress faculty featured 110 international experts leading 85 scientific sessions for a total of 88 hours of scientific learning dedicated to the most important topics in ...

Nov. 5, 2019

By Dyve Biosciences

Purchase High-Speed Automatic Labeling Machine for Pharmaceutical Packaging

Due to the characteristics of the high-speed automatic labeling machine, its development has promoted the development of the entire industry. Nowadays, automatic labeling machines have been well developed, and their types in the market are also various. In the pharmaceutical industry, the labeling machine does not seem to matter, but its presence can indeed be of great help to manufacturing. On ...

Oct. 10, 2019

By IpharMachine

Winning the War on Cancer and Counterfeit Drugs and other Inspiring Stories from LogiPharma US 2019

I just returned from the LogiPharma US 2019 held September 16-17 in Philadelphia. There were so many fascinating stories and inspiring themes that capturing all of them in a single blog post may be a challenge. Here are a few select stories: Integrated network strategy to support long term growth: Linzell Harris of AstraZeneca spoke about how having an integrated network strategy is pivotal to ...

Sep. 18, 2019

By LLamasoft, Inc.

Novel technology targets melasma

Could this new drug delivery system for tranexamic acid optimize melasma treatment? Joel Cohen, M.D., thinks it could be just what the specialty has been looking for. Researchers using a novel transdermal drug delivery system to deliver tranexamic acid deep into melasma patients’ skin found the technology-assisted treatment quickly and notably reduced the skin pigmentation of ...

Jun. 20, 2019

By Dyve Biosciences