Medical Equipment Articles
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What Are Heparins?
Heparin, also known as standard heparin or unfractionated heparin, is a linear polysaccharide consisting of 1-4 linked disaccharide repeat units of uronic acid and glucosamine residues. Heparin was discovered nearly 100 years ago and has been used clinically as a blood anticoagulant since 1935. This is due to its ability to bind to the antithrombin(serine protease inhibitor), causing the ...
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90+ reasons to smile
What happens when you bring 90+ expert dentistry and maxillofacial surgeon’s together in a room to unpack the burgeoning world of collagen membrane technology and digital dentistry? There are plenty of reasons to smile, that’s what. On Tuesday 7 August 2018, Australian regenerative medicine company Orthocell (ASX:OCC) sponsored and participated in an industry forum, Advances in ...
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Using AI to Fight a Pandemic: Insilico Medicine Announces Novel Preclinical Candidate for COVID-19 Treatment
Insilico Medicine announced the nomination of a novel preclinical therapeutic candidate for treating COVID-19, designed using the generative chemistry AI platform Chemistry42. The new drug candidate is a 3CL protease inhibitor unique from existing drugs in its class because it can be rapidly produced. While this nomination is a potentially important development for the ongoing COVID-19 pandemic ...
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Development of a Bioartificial Vascular Pancreas
Abstract Transplantation of pancreatic islets has been shown to be effective, in some patients, for the long-term treatment of type 1 diabetes. However, transplantation of islets into either the portal vein or the subcutaneous space can be limited by insufficient oxygen transfer, leading to islet loss. Furthermore, oxygen diffusion limitations can be magnified when islet numbers are increased ...
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Arterial reconstruction with human bioengineered acellular blood vessels in patients with peripheral arterial disease
Abstract Objective: Vascular conduit is essential for arterial reconstruction for a number of conditions, including trauma and atherosclerotic occlusive disease. We have developed a tissue-engineered human acellular vessel (HAV) that can be manufactured, stored on site at hospitals, and be immediately available for arterial vascular reconstruction. Although the HAV is acellular when implanted, ...
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An Early Study on the Mechanisms that Allow Tissue-Engineered Vascular Grafts to Resist Intimal Hyperplasia
Abstract : Intimal hyperplasia is one of the prominent failure mechanisms for arteriovenous fistulas and arteriovenous access grafts. Human tissue-engineered vascular grafts (TEVGs) were implanted as arteriovenous grafts in a novel baboon model. Ultrasound was used to monitor flow rates and vascular diameters throughout the study. Intimal hyperplasia in the outflow vein of TEVGs was assessed at ...
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Programmed Drug Release of rhBMP-2 for Bone Healing
Summary: Non-union of bone fractures can cause pain and disabilities. Amongst certain fracture types, in specific age groups, the incidence of non-union is over 8% in the United States and over 3.6% of all fractures in the UK. Fracture non-unions have lifelong consequences and a debilitating impact in patients' life. Bone-grafts, allografts and xenograft are currently used to treat bone ...
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Clinical implementation of the Humacyte human acellular vessel: Implications for military and civilian trauma care
ABSTRACT: The incidence of wartime vascular injury has increased and is a leading cause of mortality and morbidity. While ligation remains an option, current resuscitation and damage control techniques have resulted in vascular repair being pursued in more than half of wartime injuries. Options for vascular reconstruction are currently limited to autologous vein or synthetic conduits, choices ...
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RVx201 Herpes Vaccine
RVx201 Herpes Vaccine Description 2022 RVx201 is a first-in-human herpes simplex virus type 2 (HSV-2) live-attenuated therapeutic vaccine modified to be interferon sensitive that destroys the ability of the virus to inhibit immune responses. Produced by Rational Vaccines, Inc., the technology is based on the pioneering research of the late Dr. William Halford, who dedicated over 25 years to ...
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Susceptibility of ePTFE vascular grafts and bioengineered human acellular vessels to infection
Background: Synthetic expanded polytetrafluorethylene (ePTFE) grafts are routinely used for vascular repair and reconstruction but prone to sustained bacterial infections. Investigational bioengineered human acellular vessels (HAVs) have shown clinical success and may confer lower susceptibility to infection. Here we directly compared the susceptibility of ePTFE grafts and HAV to bacterial ...
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Experimental flow visualization (PIV) results have been presented by Prof. Dominik Obrist during the Heart Valve Society (HVS) Meeting 2022
Shear-induced Thrombogenic Potential Of A Novel Tri-leaflet Mechanical Heart Valve Prosthesis Compared To A Bioprosthetic Valve And A Bi-leaflet Mechanical Valve: In-vitro Study Of Complex Flow Patterns And Turbulence Leonardo Pietrasanta, Dominik Obrist. University of Bern, Bern, Switzerland. OBJECTIVE: Complex blood flow patterns and turbulence are principal determining factors for ...
By Novostia SA
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Minimally Invasive Stretta Therapy Gains Momentum as HCSC BCBS Adds Coverage for 16 Million New Patients
We’ve all been there. In our doctor’s office, or on the phone with their billing manager, being told that a drug or procedure we hoped for is not covered by our insurance plan. After weeks or even months of researching online, talking to other patients, and comparing alternatives, we’ve been told that our insurance plan simply will not cover that solution. Our frustration is ...
By Restech
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The difference between medical examination and surgical gloves
Medical gloves are gloves used for medical protection to prevent cross infection between doctors and patients and protect doctors' hands from injury. Medical gloves are made of natural latex, which is highly fit to the skin of the hand and provides superior comfort. Latex, nitrile, polyethylene, polyvinyl chloride and other materials can be used to make medical gloves, among which nitrile gloves ...
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Learning to Use a Bionic Hand
There is a learning curve for every prosthetic device, but for first-time users, this can seem daunting. Once fitted with a new prosthesis, users need to re-learn how to perform day-to-day functions and activities and get accustomed to their new hand. Fortunately, learning to use a bionic hand is much easier than it may seem to first-time users. Still, we've pulled together some helpful tips and ...
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Accuracy of Pulse Oximeters Intended for Hypoxemic Pediatric Patients - Case study
OBJECTIVES: Prior studies have shown inaccuracies in pulse oximetry readings at saturations less than 85%; however, no large studies have evaluated new sensors marketed for these low saturations. This study's purpose was to evaluate two sensors with claims of improved accuracy in children with saturations less than 85%. DESIGN: Prospective observational study. SETTING: Single institution; ...
By Masimo Corp
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Research Shows a Link Between Loneliness and Dementia
Humans are inherently social beings who thrive on making and maintaining social relationships. Connecting with and supporting one another forms deep bonds that make us feel seen, valued, and like we belong. These social interactions are not only important for our emotional well-being but also for our physical well-being-maybe even more so than originally thought. Loneliness, an increasingly ...
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OneThree`s Workflow for Target and Compound Discovery - Case study
Background OneThree Biotech was born out of the largest precision medicine institute in America with the purpose of decreasing the failure rate of bringing therapeutics to market using biology driven artificial intelligence. Our technology was builtin a lab setting; allowing us to engineer our methodologies around real-world results. While working with major biotech and pharma partners; ...
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Avoiding Regulatory shortfalls in the Submission Path
Commercialization of new drugsrequire careful navigation through complex regulations defined by Global health authorities. Drug development process needs extensive collaborations with internal & external stakeholders, co-ordination with cross functional teams like R&D, QA, clinical research, safety, manufacturing, supply chain, marketing, and so on. At every phase of development process, ...
By DDi LLC
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Understanding Lumbar Spinal Stenosis with Neurogenic Claudication
What is Lumbar Spinal Stenosis? Lumbar spinal stenosis, or LSS, is a common condition in which the lower spinal canal narrows and compresses the nerves in the lower back. Lumbar spinal stenosis is generally caused by aging and natural wear and tear on the spine. With lumbar spinal stenosis, thickened ligament, overgrowth of bone, and/or bulging discs in the lower back put pressure on the ...
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Improving Skeletal Traction Procedures with Arbutus Medical - Case Study
Erlanger Health System is a nationally acclaimed, multi-hospital health system anchored by a leading academic medical center. Each year, more than 600,000 people are treated by a team of healthcare professionals at seven medical centers across Tennessee and North ...
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