Medical Management Articles
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The Health Effects of Probiotics on the Human Body
Probiotics are a type of active microorganisms that play a role by improving the balance of the host's intestinal microflora. They can produce definite health effects to improve the host's microecological balance and play a beneficial role. In 2001, the World Food and Agriculture Organization (FAO) and the World Health Organization (WHO) also defined probiotics as follows: Live bacteria that can ...
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Significance of Diagnostic Enzyme Detection
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
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Food Enzymes Improves Food Processing Efficiency
Starting from a cup of coffee or milk in the morning, it seems that a vital substance—enzyme, is inseparable from modern people's dining table. In fact, not only in the food and beverage industry, but also in medical, household, health, energy, environment and other fields, enzymes are playing an important role. In the industrial enzyme industry, Creative Enzymes can be described as a ...
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The novel suspension quail cell line CCX.E10 is an ideal cell substrate for NDV virus and vector production
Newcastle disease is a highly infectious viral disease of the avian species. The causative agent is Newcastle disease virus (NDV), which belongs to the family of Paramyxoviridae. Many commercial vaccines, both live and inactivated, are available on the market and protect from NDV infection and disease. In addition, viral vectors based on Newcastle disease virus have been previously ...
By Nuvonis
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How can Nuvonis help to fight the SARS-CoV-2 pandemics?
At the end of the year 2019, a cluster of severe pneumonia of unknown cause was described in Wuhan (Eastern China) and a SARS-like acute respiratory distress syndrome (ARDS) was noted in these patients. Early in January 2020, sequencing revealed a novel coronavirus (now termed SARS-CoV-2) as the causal factor for the disease designated as COVID-19. The pandemic caused by the virus has unforeseen ...
By Nuvonis
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hVIVO used Nuvonis’ GMP Vero cells to produce Novel SARS-CoV-2 virus for a human challenge model
One of the main benefits of using Nuvonis’ fully tested GMP Vero cells is the unparalleled speed towards clinical trials. A case example from one of our customers, hVIVO: First contact with Nuvonis in July 2020, due diligence, contracting, provision of GMP Vero cells and protocols, as well as full documentation Production of GMP material in November 2020 ...
By Nuvonis
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Rho kinase inhibition in Amyotrophic Lateral Sclerosis - Case Study
REAL is a phase 2a open-label study to assess preliminary safety, tolerability, and effect on clinical outcomes as well as neurodegeneration biomarkers of BRAVYL in patients with ALS. The study will enroll approximately 20 patients, all of whom will be treated with BRAVYL for 24 weeks. ...
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Medical Battery Pack - Most Common Applications
Why Do You Need One? A medical battery pack is an essential part of any medical device. It provides power to the device when no other power source is available. This kinf of battery pack can be used on a number of devices, including portable defibrillators, heart monitors and other life-saving devices. There are many different types of medical battery pack manufacturing on the market today. ...
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Project - Sublingual Interferon-alfa (BL SLIT II)
We plan to develop sublingual interferon-alfa for the prevention of viral infections, such as influenza and coronaviruses (such as COVID-19). The rise in prevalence of viral respiratory infections in humans and increase in health care expenditure are projected to boost the growth of the global respiratory antiviral treatment market. Respiratory syncytial virus, influenza virus, parainfluenza ...
By BioLingus AG
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Bioinformatics Analysis of Viral Metagenomic Sequencing
Viral metagenomics is the study of viruses in environmental and biological samples by utilizing next generation sequencing that generates very large data sets. Viral metagenomics analyzes viral sequences to deduce the impact of viruses on the environment of human health. Unlike amplicon sequencing, metagenomics obtains and investigates genetic material directly from environmental samples, which ...
By CD Genomics
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Targeted Region Sequencing in Human Disease Studies and Clinical Care
Introduction to target region sequencing Since the introduction of Sanger sequencing in 1977, genetic sequencing has been greatly improved with costs simultaneously falling. With the ability to rapidly produce large volumes of sequencing data, next-generation sequencing (NGS) enables researchers to obtain whole genome or targeted regions of samples. Targeted region sequencing is preferred by ...
By CD Genomics
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PEG Linkers for Antibody Drug Conjugates
Antibody-drug conjugate (ADC) is one of the fastest growing fields in tumor therapy, which consists of monoclonal antibody (Antibody), linker (Linker) and active drug (Payload). So far, there are only 15 drugs on the market in the world. However, with the development of some perfect antibody modification techniques, advanced site-specific coupling techniques and powerful small-molecule toxins, ...
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Vaccine Freezers for Vaccine Storage and Handling
Vaccine Freezers are required for the safe storage of vaccines that must be kept at extremely low temperatures. Without sufficient storage, a vaccine is likely to form deviations, drastically impacting the vaccines efficiency. At Froilabo we work to support the medical and pharmaceutical industry with the equipment they require to ensure safe storage solutions. Vaccine storage has been in high ...
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Indication selection for anti-PDx combination therapy In collaboration with big pharma - Case Study
The Challenge: One of the most common challenges in immuno-oncology is identifying the indications and patient populations that would benefit from a specific therapy, especially on top of Standard of Care (SOC) treatments. Our platform tackled this challenge of indication prioritization and patient stratification for a combination of a specific target (A) with an anti-PDX drug that one of our ...
By CytoReason
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Feature Signature Discovery for Autism Detection: An Automated Machine Learning Based Feature Ranking Framework - Case Study
Abstract Autism spectrum disorder is the most used umbrella term for a myriad of neuro-degenerative/developmental conditions typified by inappropriate social behavior, lack of communication/comprehension skills, and restricted mental and emotional maturity. The intriguing factor of this disorder is attributed to the fact that it can be detected only by close monitoring of developmental milestones ...
By JADBio
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Monetizing Medical Data: Zwanger Pesiri Radiology - Case Study
Zwanger Pesiri Radiology is an innovative chain of 32 outpatient radiology centers that stretch across Long Island and New York City. Unlike many groups of imaging centers, they aren’t affiliated with any hospitals and so don’t benefit from hospital reimbursement rates or referrals. ...
By Segmed, Inc.
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Barriers to data sharing in today’s healthcare landscape
In today’s healthcare environment, the general consensus is that the exchange and flow of data is crucial and beneficial to developing better care of the patients. Healthcare information exchanges (HIEs), as an example, have shown to be effective in improving public health, reducing healthcare redundancies, and providing clinical providers with more support tools in their day-to-day work. ...
By Segmed, Inc.
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Infrared Coagulation, Fast and Pain-Free Hemorrhoid Relief
Anyone who has had hemorrhoids can tell you that it is an embarrassing and painful condition. There are many things that can cause hemorrhoids, but because they are so varied, it is often hard to pinpoint the exact cause. Regardless of how it started, though, someone who has hemorrhoids will want to get rid of them as soon as possible. Unfortunately, it is often difficult to find a good ...
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Advancing patient care for Japan`s most common cancer - Case Study
Challenge Calculating the appropriate sample size for a first of its kind stage-II colon cancer trial As Chairman of the Department of Biostatistics, Professor Satoshi Teramukai leads a variety of investigator-initiated clinical trials at the Kyoto Prefectural University of Medicine. With over 35 years experience, hundreds of published papers and thousands of citations, Professor Satoshi ...
By Statsol
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Seller beware? Why healthcare organizations are hesitant to sell their data
There are many reasons why healthcare organizations are hesitant to sell their data. For one, they may feel like they are giving up too much control over their data. Once sold, how will they know where it may end up? Will the company that purchases the data turn around and resell it? To what types of companies? How many times? In this blog post, we will explore some of the reasons why healthcare ...
By Segmed, Inc.
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