Human Health Articles
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Unveiling the Potential of Premade RNA-LNP Products
Introduction RNA Lipid Nanoparticles (LNP) technology has rapidly gained prominence in the health and scientific domain, primarily due to its significant role in carrying the mRNA of the COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. Yet, the potential of this technology spans beyond the confines of these vaccines or even the health industry. As research into premade RNA-LNP products ...
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Carbohydrate Synthesis: Understanding the Building Blocks of Life
Carbohydrates are one of the essential macromolecules that play a crucial role in the functioning of living organisms. They serve as a primary source of energy and are involved in various biological processes. The synthesis of carbohydrates is a complex and fascinating process that occurs in living organisms, allowing them to produce and utilize these vital molecules. In this blog post, we will ...
By CD BioGlyco.
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Preclinical Animal Models as A Resource to Explore Rare Diseases
Rare diseases, also known as orphan diseases, are a diverse group of disorders that affect a small percentage of the population. Due to their low prevalence and limited understanding, treating and finding cures for these conditions present significant challenges. However, preclinical animal models have emerged as invaluable resources for advancing research and unraveling the mysteries surrounding ...
By Protheragen
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What Is Metabolomics?
Metabolism is the assembly of biochemical reactions in living organisms, the material basis for life maintenance of living organisms, and an important basis for the study of life activities. Metabolomics studies the endogenous metabolic activities of life under the influence of the internal and external environments, including the detection and analysis of metabolite types and quantities and ...
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Advances in siRNA Drug Research
siRNA, with a molecular weight of about 13 kDa, recruits the RNA-induced silencing complex (RISC) to mRNA through base pairing, thereby inhibiting protein translation. The mRNA is targeted for cleavage through the catalysis of the RISC protein Ago2, a member of the Argonaute family. In addition, other Ago proteins (Ago1, Ago3, and Ago4) catalyze endonuclease-mediated degradation of non-specific ...
By BOC Sciences
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A Comprehensive Analysis of Cell and Gene Therapy
The scientific realm of biomedicine has witnessed extraordinary evolution in recent years, particularly in the spheres of cell and gene therapies. These therapies have radically revamped disease treatment modalities, transcending traditional approaches to become some of the most groundbreaking advancements in modern healthcare. This article aims to engage in an incisive analysis of cell and gene ...
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Classes and Applications of Cell-Penetrating Peptides
Classes of Cell-Penetrating Peptides There are many types of cell-penetrating peptides (CPPs), and their classification is based on physicochemical properties, sources, intake mechanisms, and biomedical applications. There is no unified conclusion yet. According to their physical and chemical properties, CPPs can be divided into three types: cationic, amphiphilic and hydrophobic, among which ...
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Single Guide RNA Libraries: Their Applications and Future Potential in Biotechnology
The phenomenal advancements in the realm of biotechnology have propelled the development of tools with remarkable potential, considerably altering the landscape of biological and medical research. One such groundbreaking tool topping the list among modern biotechnologies is the Single Guide RNA (sgRNA) library. This article will delve into the present and future applications of this revolutionary ...
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Understanding Drug-Disease Relationship Analysis: A Key to Drug Discovery
In the realm of modern medicine, the quest for new and effective drugs to combat various diseases is a continuous journey. Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial intelligence (AI). In this article, we will delve into the ...
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What Is Microbiome and How to Study It
The term microbiome comes from the Greek word micro which means small and bios meaning life. It is defined as "a characteristic microbial community occupying a reasonable well-defined habitat which has distinct physiochemical properties". Many researchers in the past defined microbiome based on different contexts such as ecological and genetic aspects. However, scientists noted some gaps in these ...
By CD Genomics
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Exploring Advanced Industrial Development Services for Probiotics
In the realm of modern health and wellness, the symbiotic relationship between humans and their gut microbiota has taken center stage. Probiotics, or "friendly bacteria," have garnered immense interest for their potential to influence various physiological processes, from digestive health to immune modulation. The expedition of harnessing the therapeutic potential of probiotics is intricately ...
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Unleashing the Power of AAV Manufacturing for Large Scale Production in Biopharma
Adeno-associated viruses (AAV) have emerged as safe and effective vectors for gene therapy and the advancement of biopharmaceutical research. Today, navigating the complex landscape of AAV manufacturing has become a focal point for professionals in the biopharma industry looking to exploit this technology in the development of breakthrough treatments. Large-scale production of AAV vectors is a ...
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How to Conduct a Sustainability Gap Analysis for Healthcare Packaging
How To Conduct a Sustainability Gap Analysis for Healthcare Packaging Sustainability in modern healthcare is fundamental for mitigating environmental impact and contributing to the health of the planet. Sustainability in the healthcare packaging industry, for instance, is crucial to effectively reduce waste, conserve valuable resources, and promote sustainable practices. To achieve these ...
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Overview of Diabetes: Prevalence Assessment, Treatment And Prevention
Diabetes is a chronic disease that affects more than 540 million people worldwide and is one of the leading causes of death and disability worldwide. In China, there are more than 114 million adults with diabetes, accounting for about a quarter of the world's diabetes patients. With the change of living and eating habits, diabetes has become the third major factor affecting human health after ...
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Breaking Barriers: Harnessing the Potential of Adjuvants in Vaccine Development
Infectious diseases seriously threaten human health, and various infectious diseases may cause millions of severe cases and even death every year. Vaccination has been one of the most effective public health interventions in history, preventing millions of deaths worldwide. However, the success of vaccines relies not only on the antigens they carry but also on additional components known as ...
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Leveraging Antibody Modeling Services to Accelerate Drug Discovery
The discovery of antibody drugs is a rapidly developing field, and antibody modeling services offer reliable and efficient tools for their discovery and design. By predicting the interactions between antibody drugs and molecular targets, antibody modeling services can enhance the affinity and specificity of antibody drugs and reduce the development time and cost. In addition to antibody ...
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Why is Air Quality important in Working Environments
The quality of the air we breathe is a fundamental aspect of living a proper life, and being able to feel well and healthy. However, while the quality of the air outside is something that we always notice, and any sign of bad outdoor air quality usually raises concerns as soon as these signs are perceived; this is not often the case when it comes to indoor air quality, which is not always taken ...
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Meet Nuritas, the bitoech using AI to identify the next generation of intelligent ingredients
As part of our quick fire questions series – or QFQs – we spoke to Dr. Andy Franklyn-Miller, Chief Medical and Innovation Officer at Nuritas about intelligent ingredients, explaining peptides and proving an AI model in life science. There is a lack of innovation within ingredients in food, many have been discovered decades ago, mostly with cost, taste and texture in mind. However as ...
By Nuritas Ltd.
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Monoaromatic Heterocyclic Chemistry: Applications and Synthesis
Summary Heterocyclic compounds with aromatic characteristics are called aromatic heterocyclic compounds, which can be classified into monoaromatic heterocycles and fused heterocycles. The common monoaromatic heterocycles are five-membered Furan, Pyrrole, Thiophene, Pyrazole, Imidazole, Oxazole, etc., and six-membered Pyridine, Pyranone, Pyridazine, Pyrimidine, Triazine, etc. Aromatic ...
By BOC Sciences
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What is the ICD code for HFpEF?
Heart failure with preserved ejection fraction (HFpEF) is currently affecting over half of heart failure patients. The Centers for Medicare and Medicaid Services (CMS) and the National Center for Health Statistics (NCHS), two departments within the U.S. Federal Government’s Department of Health and Human Services (DHHS), use the International Classification of Diseases (ICD) for coding ...
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