Necropsy Articles
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The C-Myc Oncogene Is Associated with Aging, New Study Found
The Myc gene is one of the most important drivers of cancer in mice and humans. Myc also plays a newly discovered key role in aging, according to a new study in Cell Reports by researchers at UPMC Children's Hospital of Pittsburgh and the University of Pittsburgh School of Medicine. The study, led by Edward V. Prochownik, MD, UPMC Children's Hematology/Oncology Division and Paul C. Gaffney ...
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Organoid Models of SARS-CoV-2 Infection learned from COVID-19
The clinical presentation of COVID-19-related illness ranges from asymptomatic to mild respiratory symptoms resembling influenza infection to acute symptoms including pneumonia requiring hospitalization and admission to the intensive care unit. COVID-19 starts in the upper airways and lungs, but in severe cases can also affect the heart, blood vessels, brain, liver, kidneys, and intestines. ...
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Animal study results has been be presented by Prof. Bart Meuris during the Heart Valve Society (HVS) Meeting 2021
In-vivo Evaluation Of A Novel Surgical Heart Valve Prosthesis Designed To Be Durable, Anticoagulant-free And Silent. Bart Meuris, Lucas Van Hoof, Wilm Decré, Marie Lamberigts, Tom Langenaeken, Peter Verbrugghe. KU Leuven, Leuven, Belgium. OBJECTIVE: Heart valves prostheses still face limitations: reoperations with tissue valves or lifelong anticoagulation with mechanical valves. The ...
By Novostia SA
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COVID-19 Clinical Report for Dead Infected Case
Clinical analysis of 25 novel coronavirus pneumonia deaths:asphyxia due to pulmonary mucus Pengpai news reporter Wu Yi Pengpai news ,February 29 On February 25, MedRxiv published a paper from Wuhan University People's Hospital, Clinical characteristics of 25 death cases infected with COVID-19 pneumonia: a retrospective review of medical records in a single medical center, Wuhan, China. The ...
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Formaldehyde – Protecting Hospital Workers
Formaldehyde health and safety is vital since the chemical has many uses in the healthcare industry, not just preserving bodies in the morgue. Formaldehyde is used as a disinfectant as well as a tissue preservative. As a tissue preservative, it can be found in histology labs where tissues are sectioned and prepared for microscopic analysis. Of course, autopsies can also subject the examiner and ...
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Subacute toxicity of selenium sources in mice
Sixteen groups of mice were fed diets containing different selenium species to compare their toxicity. Inorganic sodium selenate and sodium hydroselenite, elementary nanoSe, organic Sel‐Plex, and Lacto‐MicroSelenium were administered for 14 d at concentrations of 0.5, 5, and 50 ppm Se, equivalent to 0.5, 5, and 50 mg Se/kg food, corresponding to an estimated 4, 40, and 400 µg/kg bw/d Se uptake, ...
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Acute and subacute oral toxicity of polychlorinated diphenyl sulfides in mice: Determining LD50 and assessing the status of hepatic oxidative stress
Polychlorinated diphenyl sulfides (PCDPSs), a series of dioxin‐like compounds, have been detected in various environmental samples. However, information on the toxicity of these compounds is limited. In the present study, the toxic effects of PCDPSs were assessed after acute and subacute exposure in mice. Relationships between acute toxicity, number, and position of substituted Cl atoms were ...
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In ovo exposure to nonylphenol and bisphenol A resulted in dose‐independent feminization of male gonads in Japanese quail (Coturnix japonica) embryos
Sex reversal effects of nonylphenol and bisphenol A on the gonads in F1(AWE × WE) Japanese quail (Coturnix japonica) embryos were investigated using an in vivo screening model developed previously. The F1 (AWE × WE) Japanese quail are a useful avian model because sex differentiation is confirmed by the plumage color before hatching, ruled by a criss‐cross inheritance. The nonylphenol at 200, ...
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