Patient Positioning Articles
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Diabetomics Lumella - New Point-of-Care Blood Test Kit for Early Detection of Preeclampsia
Abstract Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation of synovial joints. Anticitrullinated protein autoantibodies are detected by the CCP test in early disease and predict the development of erosive disease as well as extraarticular manifestations. We recently reported that many RA patients have anti-citrullinated albumin (ACA) ...
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ADC Drugs For HER2 Positive Breast Cancer
According to the latest data, breast cancer has overtaken lung cancer to become the most common cancer among women, and the death rate is the second highest among female tumors, seriously affecting the physical and mental health of women around the world. Patients with abnormal expression of human epidermal growth factor receptor (HER2) account for 15%-20% of all breast cancers, which is highly ...
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ADC Drugs For Breast Cancer Treatment
Breast cancer is the malignant tumor with the highest morbidity and mortality among women worldwide. At present, the main therapeutic methods include surgery, chemotherapy, radiotherapy, endocrine therapy and targeted therapy, etc. The development and marketing of new drugs have far-reaching significance in improving the survival of breast cancer patients and changing the pattern of breast cancer ...
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FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer
Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases. Statistics show that about 55% of ALK-positive advanced NSCLC patients will develop brain metastases during ...
By BOC Sciences
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Clinician Attitudes are Shifting on MRD-guided Decision Making in Multiple Myeloma
This September marks four years since the 2018 Food and Drug Administration clearance for clonoSEQ to detect and monitor minimal residual disease (MRD) in bone marrow from patients with acute lymphoblastic leukemia (ALL) and multiple myeloma (MM). In the years following, researchers have explored the value of using MRD status to guide treatment in blood cancers – and the mounting ...
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Extentrac Elite Case - Case study
Clinical Study Report A practice based prospective study of 31 consecutive patients (21 men, 10 women – mean age 57 years) with low back pain with or without radiculopathy. Each patient completed the Oswestry Low Back Pain Disability Questionnaire (Ver.2) and the Numeric Rating Scale (NRS-11) – pre and post treatment. Disability assessment was based upon an absolute percentage point ...
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Spine-Intra-Abdominal Pressure (SIAP) - Case Study
The SIAP study investigates the effect of using Ergotrics' Inflatable Prone Support (IPS) on intra-abdominal pressure (IAP) during spine surgery. Study background The objective of this study is to demonstrate the ability of the inflatable Prone Supports (IPS) to lower the IAP of patients in the prone position. Whenever the patients’ position is changed to prone, the IAP is increased due to ...
By Ergotrics NV
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How to choose the right pliers to make the work more efficient?
Pliers are a multi-purpose hand tool with opposing jaws for gripping, bending and cutting. Pliers are an important part of every toolbox because they have multiple uses for the home. Whether you are an apprentice, hobbyist, handyman, machinist, or just someone who enjoys building and tinkering with mechanical objects, you need to know which tools are best for each project or repair. Knowing which ...
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Zanidatamab, a HER2-targeted bispecific antibody, in combination with docetaxel as first-line therapy for patients with advanced HER2-positive breast cancer: Preliminary results from a Phase 1b/2 study (American Society of Clinical Oncology)
Worldwide, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer deaths in women, with over 650,000 deaths in 2020.1,2 Human epidermal growth factor receptor 2 (HER2)-targeted agents have improved outcomes in HER2-positive breast cancer, but most patients in first-line therapy do not respond to current therapies, eventually relapse or develop ...
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Micromate™ Case Report: Robot-Guided Bone Biopsy
Micromate™ Case Report series presents real cases performed by the physicians currently using our full-fledged robotic platform for percutaneous procedures. Today, we join Dr. Alexander Kupferthaler, Interventional Radiologist at the Ordensklinikum Linz – Barmherzige Schwestern, for a robot-guided bone biopsy. Clinical Context 65-year-old female with invasive lobular carcinoma of ...
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How IFIX Can Help With Contrast Shortage
Why is there a shortage of CT contrast? The COVID-19 pandemic continues to be the root cause of disruptions in the global supply chain. This time, it led to the temporary shutdown of a production facility in Shanghai, creating a severe shortage of iodinated contrast media (ICM) and affecting imaging facilities – especially in the US, with the American Hospital Association expressing its ...
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Infiltrating Ductal Carcinoma (IDC) - Case Study
Patient with positive family history of breast cancer and ovarian cancer. September 2003 mammogram reported benign micro calcifications. August 2007 patient presented with a palpable mass in lateral aspect of left ...
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Diagnostic Radiology Consultants - Chattanooga - TN- Case Study
CAD PRO® Advantage Digitizer Provides Mammography Workflow Solution for Innovative Radiology Practice. For more than 50 years, Diagnostic Radiology Consultants (DRC) has pioneered imaging services in the tri-state area of Tennessee, Georgia, and Alabama. The innovative group, including 11 radiologists at 12 sites, often is the first to offer emerging technologies that positively impact ...
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Importance of hemodynamic monitoring during esophagectomy - Case Study
Background Esophagectomy for cancer involves two- or three-phase procedures, such as abdominal, chest and/or neck incisions, is more invasive than other types of gastrointestinal surgery, and is associated with high risk for postoperative morbidity. Because of this risk, perioperative management of circulatory conditions such as hypovolemic hypotension is especially important to avoid ...
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Three generations of ADC: Nearly a decade of development-PII
Kadcyla and second-generation non-cleavable linkers Alternative linker design methodologies are still under development. Immunogen discovered a very powerful ADC by an accidental discovery. The lysine residue of trastuzumab is linked to DM1 via a non-cleavable linker containing N-succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC), an ADC (T-DM1, Kadcyla) authorized by the FDA in ...
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Micromate™ Case Report: Robot-Guided Type II Endoleak Embolization
Micromate™ Case Report series presents real cases performed by the physicians currently using the world’s smallest robot for percutaneous procedures. Today, we join Drs. Gerlig Widmann and Martin Freund, Interventional Radiologists at the Tirol Kliniken, for a robot-guided type II endoleak embolization. Clinical Context Patient’s profile: Male patient, previously subjected ...
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Representative structures of FDA-approved ADCs
Since they were originally explored in animal models in the 1960s, antibody-drug conjugates (ADCs) have seen many booms. The initial ADC clinical studies took place in the 1980s, and Mylotarg, the first ADC drug, was approved in 2000. The removal of Mylotarg, however, came as a huge shock to the industry, and it was relaunched in 2017. The launch of a number of clinically and commercially ...
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Balance Error Scoring System with force/pressure platform
A look at the Balance Error Scoring System with force/pressure platform The Balance Error Scoring System (BESS) is a well-known tool to evaluate the effects of a head injury on static postural stability, or standing still in different positions. This protocol is often used in athletes after sport-related concussions or mild traumatic brain injuries (TBIs) [1]. BESS was developed by researchers ...
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Dynamic Surgical Guidance to Facilitate Dental Implant Placement
The long-term success of dental implant surgery is dependent, in part, on accurate planning and placement of the implant.1 Currently, there are many digital planning systems available to aid the clinician in pre-operative treatment planning, although the main challenge with these planning systems is to accurately transfer the digital plan to the clinical situation. Most systems involve taking a ...
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The COVID-19 crisis hit the world health sector – Italian Aosta Valley Regional Hospital searched for the most effective solution - Case Study
During the Covid-19 emergency, from March to April 2020, up to 9 departments dedicated to the care of patients affected by corona were set up in the Aosta Valley regional hospital and the resuscitation places were tripled The staff of the Aosta Valley Hospital consists of more than 2,100 employees with 310 doctors and 700 nurses 127 beds and 28 resuscitation places dedicated to Covid-19 ...
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