Medical Monitoring Articles
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Novel Biomarkers May Help Predict the Susceptibility of a Population to Rheumatoid Arthritis
Genetics (i.e., mutations) are considered to be the main factor predisposing to the etiology of rheumatoid arthritis (RA), but they account for only a few changes in RA disease risk, and in contrast to genetics, the environment may have an important impact on epigenetic properties associated with disease etiology. Recently, in a study published in the journal Scientific Reports entitled ...
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Special Genes May Affect the Level of Lipopolysaccharide in the Body’s Blood
Transfer of lipopolysaccharide from gram-negative bacteria into the systemic circulation of the body leads to the development of endotoxemia, which is detected in cardiometabolic diseases such as cardiovascular disease and obesity in addition to acute infections. Lipopolysaccharide is a virulence factor produced by bacteria, which often triggers systemic inflammation through the body's ...
By CD BioGlyco.
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IMOGEN - Contrast-Free Magnetic Resonance Imaging for Breast Disease - Case Study
This is an observational cohort study looking at women, 30 years of age or older with a concern or at risk of suspected breast disease or breast cancer. The proposed study aims to examine the diagnostic performance of non-contrast MRI in breast disease by applying quantitative multiparametric MRI ...
By Perspectum
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West Hertfordshire IBD technology study - Case Study
Observational study with retrospective and prospective data collection, for total of 24 months. This is an IBD technology study investigating quantitative metrics for endoscopy, histology and radiology for improved diagnosis and assessment of ...
By Perspectum
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Detailed Introduction to Steroids Analysis
Steroid hormone is a class of compounds that contain cyclopentane polyhydrophenanthrene structure formed by cholesterol and catalyzed by cytochrome P450 enzymes. Steroid hormones mainly include adrenocorticotropic hormones secreted by the adrenal cortex and sex hormones secreted by the gonads, which are mainly divided into four categories: progesterone, corticosteroid, estrogen and androgen. ...
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RADIUS - Developing new and improved MRI imaging protocols - Case Study
This study aims at developing new and improved MRI imaging protocols in order to obtain better quality images and improved/reduced scan time. We will also assess whether multi-parametric MRI imaging of multiple organs gives the same results when it is repeated on the same person after a period of time, and when it is performed on the same person in different MRI scanners. We hope that, by running ...
By Perspectum
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UK Imaging Diabetes Study Seeing Diabetes Clearly - Case Study
Prospective observational cohort study with clinical outcomes data collection. Recruiting adult patients with type 2 diabetes (T2DM) and diabetic retinopathy (DR), who lack history of cardiovascular ...
By Perspectum
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New Study Findings about Glycoprotein PTGDS
Glycoprotein prostaglandin D2 synthase (PTGDS) is a member of the lipocalcitonin superfamily that plays a dual role in prostaglandin metabolism and lipid transport. PTGDS is involved in various cellular processes including solid tumorigenesis, but its role in tumorigenesis is paradoxical, and the significance of PTGDS in hematologic malignancies is not clear. The aim of this new study was to ...
By CD BioGlyco.
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The Mode of Action of Basic Proteins Involved in Cancer and Alzheimer's Disease Found
These proteins belonging to the HAT family are essential for life because they transport amino acids to the cell membrane. Although members of the family are nearly identical, they selectively transport certain amino acids. This specificity determines their involvement in specific functions, such as cell growth or neuronal function, and consequently in related diseases, such as cancer or ...
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Researchers highlight the impact of COVID 19 pandemic on patients with cancer
New collaborative research from Queen’s University Belfast, the University of Split, Croatia and King’s College London has shown that the response to the outbreak of the coronavirus disease 2019 (COVID-19) is significantly affecting the treatment and care of patients with cancer. The research, recently published in the European Journal of Cancer, highlights how the repurposing of ...
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InterSystems Survey Finds Asian Private Hospitals Expanding Digital Capabilities to Support Patient-focused Transformation
Private hospitals in South East Asia will dramatically expand the capabilities of their healthcare information systems over the next five years to support transformational changes such as value-based care initiatives and better care coordination, according to a survey by InterSystems, a global leader in information technology platforms for health, business and government. “Private ...
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Science: Knockout of this epigenetic gene gives CAR-T cells the ability to continuously attack cancer cells
Simply put, CAR-T is to transform the patient's immune T cells in vitro by biotechnology, so that they recognize antigens on the surface of tumor cells, and then inject these cells back into the patient to achieve the therapeutic effect of recognizing and killing cancer cells. In 2017, CAR-T therapy was first approved by the FDA for the treatment of blood cancers such as leukemia and lymphoma. ...
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A disability isn’t always visible!
In recognition of the International Day of Persons with Disabilities, we hear from one of our #SEGreatPeople on their experience of life with a ...
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California Prop65 list
1. Tetrahydrocannabinol (THC) Tetrahydrocannabinol (THC) is an active ingredient in Nabiximols, a specific extract of Cannabis that was approved as a botanical drug in the United Kingdom since 2010 as a mouth spray for people with multiple sclerosis to reduce neuropathic pain, spasticity, overactive bladder, and other symptoms. Nabiximols (as Sativex) is available as a prescription drug in ...
By ComplianceXL
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Targeted Capture and Sequencing: An Accurate and Efficient Method for Human Pathogen Detection
Next-Generation Sequencing or NGS has provided scientists alternative approaches in understanding DNA. The technology has come a long way from the simple sequencing technique developed by Sanger in 1977 and continuous improvements are being done to better cater to the needs of researchers. One of the recent advances to NGS is Target-and-Capture Sequencing or Capture-Seq. Capture-Seq allows the ...
By CD Genomics
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The pros of plastic in the medical industry
Plastic has been on the receiving end of a lot of bad publicity. A fair percentage of this is justified. There are, however, some environments where the benefits of plastics, even single-use plastics, far outweigh the disadvantages. The medical industry is one of them. Here are just some of the benefits of plastics in the medical industry.HygieneProbably the single, biggest benefit of plastics ...
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Metabolomics in Gut Microbiota Research
With rapid development in sequencing technology, researchers can better assess the effect of the gut microbiome on human health. Human beings have a symbiotic relationship with the microbiota since birth. The environment, proximity to other humans and animals, diet, genetics, and time changes can all affect the microbial composition of our skin, mouth, and intestines. Compared with other ...
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MC3R Links Nutritional Status to Child Growth and Pubertal Timing
Scientists have determined how a protein in the brain uses information about the body's energy balance to regulate children's growth rate and the onset of puberty. The study focuses on the melanocortin 3 receptor (MC3R), a member of the protein family, which has long been thought to play an important role in metabolism and energy balance. Roger Cone, a physiologist at the University of ...
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CD Genomics Perspective: The Application of RNA-Seq and DNA-Seq in Cancer Research
Clinicians can make better diagnostic and treatment decisions using the data obtained by next-generation sequencing (NGS) technologies. Breast cancers, for example, have typically been diagnosed using mammography, physical exam, and histology. Genetics became more significant after the discoveries of oncogenes and other biomarkers. Today, commercially available microarray-based tests enable more ...
By CD Genomics
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Amplicon Sequencing for Microbiome Research: Introduction, Advantages, and Applications
The identification of microbial groups is an important step in understanding the interrelationship of microorganisms in a community. It is done to determine all present microbial taxa and their relative abundance, and as well their phylogenetic relationships. One of the methods used to establish phylogenetic relationships is by sequencing common genes. One of the easiest genes to be sequenced are ...
By CD Genomics
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