Nuclear Medicine Articles
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Unveiling the Role of CDH1 Protein in Cancer and Future Research Directions
Introduction CDH1, also known as E-cadherin, is a crucial protein involved in cell adhesion and plays a significant role in various biological processes. In recent years, researchers have focused on understanding the functions of CDH1 and its implications in cancer development. This blog post aims to shed light on what CDH1 protein does, its role in cancer, and the future research directions in ...
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An Overview of Isotopes
What are Isotopes? Isotopes are different atoms of the same element with the same number of protons and different numbers of neutrons called isotopes of each other, which can also be interpreted as different nuclides of the same element called isotopes of each other. An isotope is one of two or more atoms of the same chemical element with the same atomic number, occupying the same position on the ...
By BOC Sciences
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Glucose metabolism: key to neurodegenerative diseases
Previously, it was thought that glial cells, which support neuronal activity, metabolize most of the glucose in the brain. However, by using induced pluripotent stem cells, the researchers found that neurons were able to take up glucose and process it into smaller metabolites. In mice, normal function of neurons depends on glycolysis. The findings could help develop new treatments for ...
By CD BioGlyco.
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Teleradiology in Covid-19
The start of coronavirus pandemic pushed limits of healthcare systems all over the world by causing thousands of deaths and the requirement of a huge quantity of healthcare resources. When WHO declared COVID19 as a pandemic, the whole world came to standstill. Half of the world population is confined to their home except for essential services. In the year 2016, when GOI announced ...
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Why PET Will Beat SPECT
The next generation of positron emission tomography (PET) imaging agents will herald an age when PET will eclipse single photon emission computed tomog- raphy (SPECT) as the “go to” modality for molecular imaging. It will do so by enabling personalized medicine through precision diagnostics, the ability to be delivered cost-effectively in a manner with less radiation to patients, by ...
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The Barbara Ann Karmanos Cancer Center - Case study
The Barbara Ann Karmanos Cancer Center, located in midtown Detroit, is the only National Cancer Institute (NCI)-designated comprehensive cancer center in metro Detroit and one of just 51 centers of its kind in the United States. The comprehensive cancer center designation means patients can access treatments exclusive to Karmanos, as well as clinical trials, cancer prevention programs, and ...
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Automatically Diagnosing HER2 Amplification Status for Breast Cancer Patients Using Large FISH Images
Fluorescence in situ hybridization (FISH) is a technique that prepares acceptable results for molecular imaging biomarkers to precisely and dependably detect and diagnose disorders which are sign of cancers. Since contemporary manual FISH signal analysis is low-effective and inconsistent, it is an attractive research area to develop automated FISH image scanning systems and computer-aided ...
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Good News for Cancer and Heart Disease Patients
Good News for Cancer and Heart Disease Patients: US Nuclear Partner Achieves Critical Milestone Proving New Way to Fill Multi-Billion/Year Shortage of Radioisotopes for Diagnostics and Treatments The National Academies of Sciences, Engineering and Medicine warns about severe shortages of radioisotopes that are required to non-invasively diagnose heart disease, cancer, other health issues, and ...
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A Historic Breakthrough in Physics for Cancer and Heart Patients
DENVER, CO / ACCESSWIRE / September 5, 2018 / A significant milestone has been reached in nuclear fusion by MIFTEC Laboratories, Inc. when they recently exceeded 1010 neutrons per pulse power level. This level of neutron flux is close to that which is needed to commercially produce radionuclides for nuclear medicine, and validates previous claims regarding the commercial viability of their ...
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Lucas Heights Reactor Shutdown Highlights Need for US Nuclear Corp. Technology
DENVER, CO / ACCESSWIRE / July 16, 2018 / On June 22nd a mechanical failure at the Lucas Heights nuclear reactor in Sydney, Australia shined a light on the tenuous supply chain of medical radioisotopes worldwide. These isotopes are key tools in both diagnosis and treatment for a wide range of medical conditions. The mechanical error at the Sydney plant sent hospitals throughout Australia and ...
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U.S. Nuclear Corp. Partners with Fusion Power Leader
DENVER, CO / ACCESSWIRE / January 30, 2018 / US Nuclear (OTC PINK: UCLE) recently announced it signed a preliminary agreement with MIFTEC, a subsidiary of MIFTI, to become the exclusive contractor to manufacture medical isotope generators in the nuclear medicine market. MIFTI Nuclear Fusion was recognized and awarded by the U.S. Department of Energy, ARPA-E, for their innovative approach ...
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A Raman-based endoscopic strategy for multiplexed molecular imaging
Endoscopic imaging is an invaluable diagnostic tool allowing minimally invasive access to tissues deep within the body. It has played a key role in screening colon cancer and is credited with preventing deaths through the detection and removal of precancerous polyps. However, conventional white-light endoscopy offers physicians structural information without the biochemical information that would ...
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A computational tool for evaluating the exposure risk in nuclear medicine treatments
A computational tool was developed with the aim of evaluating radiation exposure levels corresponding to patients and other exposed people, such as medical staff or chaperones, during typical nuclear medicine procedures. The calculation system is based on Monte Carlo subroutines adapted from the code PENELOPE and devoted to perform energy deposition according to the user-defined set-up. The ...
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EU normative framework and standards of radiological protection in medicine
This paper examines the normative framework of the European Union (EU) and member states in the field of radioprotection of individuals undergoing medical exposure, in the light of harmonisation on the basis of the European Atomic Energy Community (EAEC or EURATOM) directives and enforcement at the national level. It discusses to what extent medical standards in radioprotection vary in member ...
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Molecular imaging with targeted quantum dot bioconjugates: the need for contrast optimisation studies
Quantum dots have the potential to be used as contrast agents for molecular imaging in vivo, but there are many challenges in optimising such procedures, both in pre-clinical animal models and in the potential clinical applications. In particular, it is critical to obtain the optimal target-to-background contrast to achieve maximum diagnostic accuracy. However, available data are insufficient to ...
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Mir-21 promotes glioma invasion by targeting mmp regulators
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Departments of Neurology and Radiology, Massachusetts General Hospital and Neuroscience Program, Harvard Medical School, Boston, Massachusetts, USA; Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, ...
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The estimation of the effective dose to a population from nuclear medicine procedures in north of Iran
Despite extensive research over the last decades, there remain considerable uncertainties as to the risks of low doses of ionising radiation as encountered in nuclear medicine. The effective dose to a population is a very important factor in the estimation of risk. The main goal of this study is to determine the effective dose to members of the public from diagnostic nuclear medicine in the ...
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Chromosomal aberration analysis in lymphocytes from workers exposed to I-131 in nuclear medicine departments in Iran
In order to evaluate the cytogenetic effects of low doses of radiation by internal or external exposure to iodine-131, we analysed chromosomal aberrations (CA) in peripheral blood lymphocytes from 34 subjects working in the nuclear medicine departments in Iran. The studied groups consisted of 26 individuals (Group A) who were employed in these centres without any evidence of radiation exposure by ...
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