Medical Specialties Articles
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Comparison and Analysis of SMDC, ADC, and DAC
In order to more effectively deliver chemotherapy drugs, Small Molecule Drug Conjugates (SMDC), Antibody Drug Conjugates (ADC), and Degradation Antibody Conjugates (DAC) have been successively explored and developed, enhancing the therapeutic index while providing selective delivery. What are their similarities and differences? What are their respective advantages? What is the current status of ...
By BOC Sciences
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The Difference Between Span 60 and Tween 60
Span 60 Span 60 is referred to as S60, its main chemical composition is dehydrated sorbitol stearate, the appearance is yellowish waxy solid. Span 60 is an excellent oil-in-water emulsifier with wetting and diffusion properties. It can also be used as a fiber post-processing softener to eliminate static electricity on the fiber to improve softness. Span 60 is harmless to the human body, so it is ...
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Electrospinning Technology of Recombinant Human Collagen
Electrospinning can produce continuous fibers on the micro - and nano-scale. The high flexibility and low cost of the material make electrospinning very attractive. In addition, the high specific surface area, porosity, and similarity to ECM ensure that the electrostatic pad promotes cell adhesion, skin regeneration, nutrient and oxygen transport, moisture retention, exudate removal, and ...
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Food Nutrition Enhancers
Food nutrition enhancer, also called food nutritional fortifier, refers to natural or synthetic nutrients added to food in order to increase its nutritional content. It can not only supplements people's daily nutritional intake, but also has a positive effect on disease prevention and control. The food nutrition enhancers can be divided into four main categories as following. Vitamins Vitamins ...
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Classification of Excipients for Transdermal Drug Delivery System
Transdermal drug delivery system is a type of drug formulation that is absorbed into the body circulation through capillaries at a certain rate through the skin to produce drug effects. Transdermal drug delivery systems allow the drug to continuously diffuse through the skin, penetrate and absorb into the blood circulation, maintain stable blood concentrations for a long time, reduce the ...
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The Advantages of Exenatide Microneedle Patch Preparation Technology
The backing layer is prepared with the same polymer solution as the needle tip, and polyvinyl alcohol is used as the backing film-forming material to support the microneedle fractions, so that the backing layer has a tight bond with the microneedle tip, and the backing film and the needle tip can be consistently detached from the mold when the film is uncovered, without the problem of process ...
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In Vivo Biotin Recombinant Antibodies
Yeast produces biotinylated recombinant antibodies in vivo. Researchers have now developed a new method to generate in vivo biotinylated recombinant antibodies secreted by yeast. In vivo biotinylation supports efficient biotinylation for accurate testing. Yeast is a single-celled fungal organism that has played an important role in the field of biogenetics in recent years. Based on the expansion ...
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NEBS and PIEZO2: Guardians of the Respiratory Galaxy
In a recent Nature publication by Schappe,M (2024), researchers have revealed a fascinating aspect of respiratory physiology: the role of sensory neurons in guarding against airway obstruction and orchestrating crucial reflexes to maintain respiratory function. The study explores the intricate neural pathways involved in detecting and responding to airway closure. By characterizing a ...
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Understanding the Different Levels of CPR Training
CPR training is more than just a certification; it’s a crucial skill that can save lives in critical situations. In Kentucky, where industries range from manufacturing to healthcare, the demand for comprehensive CPR and first aid training is ever-present. The different levels of CPR training are designed to meet specific needs – from basic techniques for laypersons to advanced ...
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The Average Cost of CPR Training In Kentucky
Discussing the cost of CPR training is not merely a financial decision but a strategic move toward enhancing workplace safety. The cost varies based on several factors, including the complexity of the training, the level of certification required, and the number of participants. For companies, understanding these cost components is essential to make informed decisions. The value of CPR training ...
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6 Steps To Getting A CPR Certification In Kentucky
In Kentucky, the significance of CPR certification extends far beyond a mere qualification. It’s about empowering individuals with the ability to make a crucial difference during emergencies. Each year, situations arise where immediate and knowledgeable action is essential. Being trained in CPR means not only responding to a crisis but doing so with the proficiency and confidence that can ...
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How to Apply In Vitro DMPK Services to Support Drug Development and ADMET Study
Drug development is a complex and multifaceted process that involves extensive research and testing to ensure safety, efficacy and quality for human use. One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. In vitro DMPK services, along with ...
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A Closer Look at Reporter Lentiviral Particles: Tool for Biomedical Research
Introduction For years, scientists have leveraged the brilliant potentialities of genetic science to explore how cells function and interact in living organisms. Among the numerous tools employed are "reporter systems," which use a visible marker to track gene expression, protein interactions, and other vital biological processes. One such system employs reporter lentiviral particles, using the ...
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Unleashing the Potential of Bacterial Genome Editing: A Gateway to the Future
Technological advancements and innovative research have continuously led to the discovery and development of new methodologies in the field of biological and medical sciences. One such breakthrough discovery is bacterial genome editing, which opens a new world of opportunities and challenges in the field of biotechnology and genomics. Understanding Bacterial Genome Editing Bacterial genome ...
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Unveiling the Potential of Premade RNA-LNP Products
Introduction RNA Lipid Nanoparticles (LNP) technology has rapidly gained prominence in the health and scientific domain, primarily due to its significant role in carrying the mRNA of the COVID-19 vaccines developed by Pfizer/BioNTech and Moderna. Yet, the potential of this technology spans beyond the confines of these vaccines or even the health industry. As research into premade RNA-LNP products ...
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Unleashing the Potential of Recombinant Adeno-Associated Virus (rAAV) Particles in Gene Therapy
Recombinase Adeno-Associated Virus (rAAV) particles have taken the center-stage in gene therapy research and development due to their exceptional genetic manipulation capabilities, safety and unprecedented therapeutic success. As biomedical science advances, there is an ever-increasing enthusiasm in the usage of rAAV particles as effective vehicles for gene delivery and the subsequent therapy. ...
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CpG Oligodeoxynucleotides Synthesis
Creative Biogene is one of the leading biotechnology companies which has the expertise and ability in providing CpG oligodeoxynucleotides synthesis service for customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to assist you synthesis your interested CpG oligodeoxynucleotides. Creative Biogene's goal is to provide ...
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An In-depth Analysis of hERG (IKr, Kv11.1): Its Function, Role, and Importance
Introduction hERG, which stands shorthand for the human Ether-à-go-go-Related Gene, generates the protein responsible for a certain type of potassium channel in the human heart, denoted as IKr or Kv11.1. The role of this potassium channel is fundamental for normal cardiac function, playing a vital role in the termination of the cardiac action potential and ultimately contributing to the ...
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The Role of Flavoring Agents, Buffers, Plasticizers, and Fragrance Agents in Cosmetics
Introduction Cosmetic products have become an integral part of our daily lives, enhancing our natural beauty and boosting our self-confidence. Behind every cosmetic product lies a complex formulation consisting of various ingredients. Among these ingredients, flavoring agents, buffers, plasticizers, and fragrance agents play crucial roles in enhancing the user experience and improving the overall ...
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The Science Behind Dietary Supplements: Exploring Efficacy and Safety of Popular Ingredients
Dietary supplements have become increasingly popular in recent years as individuals seek to optimize their health and well-being. When it comes to popular dietary supplement ingredients, several categories stand out, including vitamins, minerals, amino acids, enzymes, botanicals, and more. Each of these components plays a crucial role in supporting various physiological functions in the human ...
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