Cancer Radiotherapy Articles
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Lehigh Valley Health Network: External Beam Electron Treatment with 3D Printed Modulated and Simple Bolus - Case Study
This patient case demonstrates the clinical application of Adaptiiv’s technology used in radiation oncology through the design and fabrication of both modulated and uniform thickness (simple) ...
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Scripps MD Anderson Cancer Center: SCC of Right Index Fingernail - Case Study
The following patient case demonstrates the application of Adaptiiv’s technology used in clinical radiation oncology through the design and fabrication of customized bolus to improve the efficacy of treating complex target volumes with electron beams. This case is a great example of how a custom modulated electron bolus (MEB) allowed for a uniform dose distribution of a complex treatment ...
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Bilateral Insufficiency Fractures in an Oncology Patient Treatment with the CurvaFix IM System - Case Study
CASE PRESENTATION A 70-year-old female recently diagnosed with metastatic pancreatic cancer presented with acute new onset of lower back pain. The patient was taking chemotherapy, participating in a drug therapy trial, and had received radiation therapy. There was no history of acute trauma to the pelvic or acetabular region. Magnetic resonance imaging revealed bilateral fragility fractures, with ...
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Expression Genomics of Cervical Cancer: Molecular Classification and Prediction of Radiotherapy Response by DNA Microarray
Purpose The incidence and mortality rates of cervical cancer are declining in the United States; however, worldwide, cervical cancer is still one of the leading causes of death in women, second only to breast cancer. This disparity is at least partially explained by the absence of or comparatively ineffective screening programs in the developing world. Recent advances in expression genomics have ...
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CAR-T Cell Anti-Cancer Therapy Ushered in A Revolutionary Breakthrough!
Chimeric antigen receptor T cells (CAR-T) and T cell antigen receptor chimeric T cells (TCR-T) are currently the "top stream" in adoptive T cell tumor immunotherapy. In particular, CAR-T therapy, which has been approved by the FDA, is rewriting the treatment paradigm of some hematological tumors. However, adoptive T cell therapy remains of little success in solid tumors. The main reason is that ...
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Link Between Periodontal Disease and Oral Cancer
There is a strong relationship between periodontal disease and oral cancer. In patients with tongue cancer, the periodontal disease preceded the tongue cancer. Although periodontal disease and oral cancers are both located in the mouth, until recently, there was never thought to be a connection between the two. New evidence is coming to light to show that those with periodontal disease increase ...
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How Respiray can protect people with a weakened immune system
As countries worldwide start relaxing rules and lifting coronavirus restrictions, including wearing face masks in public, people with a weakened immune system may still need to protect themselves against airborne viruses and benefit from cleaner, purified air. ...
By Respiray OU
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How the Breuer Lab tracks their sample information at every step of their research
Dr. Eun-Kyoung Breuer is an Assistant Professor and an Associate Director of the Radiobiology Program in the Department of Radiation Oncology at Loyola University Chicago. Her lab's research focuses on understanding the role that tumor suppressor genes play in the DNA damage response pathway and in breast cancer regulation. A centralized information management approach Doing research focuses on ...
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The Promoter of Life Evolution—Superoxide Dismutase
More and more scientific evidence shows that reactive oxygen species (ROS) and reactive nitrogen species are important mediators of signaling events in cells, especially the superoxide anion in reactive oxygen species. If the content of superoxide anion in the human body is too high, it may induce various diseases, including pro-inflammatory diseases (pro-inflammatory diseases), cardiovascular ...
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Gamma delta T cells in tumor immunotherapy
Immunotherapy, in addition to surgery, chemotherapy, and radiotherapy, has now become the fourth pillar of anticancer treatment, with T cell-based immunotherapy being a successful cancer treatment technique. T cells can be separated into two subpopulations based on the expression of T-cell receptors (TCRs). αβ T cells, expressing expressing αβ TCR, recognize peptide antigens, such as those ...
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Science: Knockout of this epigenetic gene gives CAR-T cells the ability to continuously attack cancer cells
Simply put, CAR-T is to transform the patient's immune T cells in vitro by biotechnology, so that they recognize antigens on the surface of tumor cells, and then inject these cells back into the patient to achieve the therapeutic effect of recognizing and killing cancer cells. In 2017, CAR-T therapy was first approved by the FDA for the treatment of blood cancers such as leukemia and lymphoma. ...
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Targeted Therapy of Intracellular Oncoproteins by Peptide-centered CAR T Cells
Researchers at the Children's Hospital of Philadelphia (CHOP) have made a breakthrough in the treatment of aggressive solid cancers, and they have developed a new cancer treatment that targets proteins within tumor cells that are essential for tumor growth and survival, but this has not been possible before. Using the power of large data and advanced computational methods, researchers can ...
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The Function and Application of the Magic Superoxide Dismutase
Some substances can easily interact with the oxygen in the air when exposed to the air, causing chemical changes in the substance. This is the process of oxidation. Sun exposure, air pollution, radiation, etc. will cause the human skin to produce a large amount of superoxide free radicals, and its strong oxidizing ability will accelerate the speed of skin oxidation, and may even cause serious ...
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The New Guidelines For Interventional Oncology - And How Micromate™ Seamlessly Fits Into Them
Interventional Oncology, the 4th pillar of modern cancer care Until the late 90s, modern cancer care consisted of three pillars of treatment: surgery (through tumor resection), radiation therapy, and chemotherapy. These pillars address tumors directly, removing or destroying lesions. Although immunotherapy specialists devised ingenious ways to use the patients’ own immune system to better ...
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Temple research finds that tweaking CBD may help it curb pain and opioid use in mice
Doylestown-based Neuropathix is running safety tests required to start clinical trials in humans. The compound may help with neuropathy, a severe type of chronic pain associated with cancer treatment. The next generation of cannabis-inspired medicine might be grown in test tubes instead of greenhouses. Researchers at Temple University have partnered with Doylestown-based pharmaceutical company ...
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Commissioning of an ultra-high dose rate pulsed electron beam medical LINAC for FLASH RT preclinical animal experiments and future clinical human protocols - Case Study
Purpose To present the acceptance and the commissioning, to define the reference dose, and to prepare the reference data for a quality assessment (QA) program of an ultra-high dose rate (UHDR) electron device in order to validate it for preclinical animal FLASH radiotherapy (FLASH RT) experiments and for FLASH RT clinical human protocols. ...
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Self-Shielding for the ZAP-X: Revised Characterization and Evaluation
Abstract The ZAP-X® is a newly designed, self-contained, and first-of-its-kind self-shielded therapeutic radiationtherapy device dedicated to brain and head and neck stereotactic radiosurgery (SRS). By using an S-bandlinear accelerator (linac) and employing integrated minimal but sufficient shielding, the ZAP-X does nottypically require a radiation bunker. At the same time, the self-shielded ...
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ZAP Surgical Receives CE Mark Clearance for its ZAP-X Gyroscopic Radiosurgery Platform
ZAP Surgical Systems, Inc. today announced it has received CE mark clearance to the new EU MDR for its ZAP-X® Gyroscopic Radiosurgery® platform. The CE mark makes it possible for healthcare providers to begin treating patients with the ZAP-X system in the European Union. For select indications including many primary and metastatic brain tumors, stereotactic radiosurgery (SRS) is proven ...
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Novel Tumor Bed Marking in Breast Cancer: Expanding Beyond Lumpectomy
VeraForm® placement to assist with localization and delivery of adjuvant radiation Historically, lumpectomies resulted in a scar immediately over the lumpectomy site, dictating delivery of adjuvant radiation on scar location, and frequently on the presence of a seroma. Currently, the question persists as to the optimal means to help direct the radiation oncologist to effectively deliver ...
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Intraoperative Radiation Therapy (IORT) with VeraForm: Marking for Variability
Radiation therapy choices vary for comprehensive breast cancer treatment. One such option, intraoperative radiation therapy (IORT) is employed in many centers around the country. IORT using the Zeiss® Intrabeam® System has been proven to be non-inferior to External Beam Radiation Therapy (EBRT) in local recurrence and disease-free survival. IORT’s advantage is one treatment during ...
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