Gastroenterology Articles
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The Science Behind Dietary Supplements: Exploring Efficacy and Safety of Popular Ingredients
Dietary supplements have become increasingly popular in recent years as individuals seek to optimize their health and well-being. When it comes to popular dietary supplement ingredients, several categories stand out, including vitamins, minerals, amino acids, enzymes, botanicals, and more. Each of these components plays a crucial role in supporting various physiological functions in the human ...
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Exploring the Intricate Link Between Bile Acids and Disease
Bile acids are synthesized in the liver from cholesterol as a raw material. As a natural "emulsifier", they can promote the dissolution, digestion and absorption of fats, fat-soluble vitamins, etc. Meanwhile, as an important signaling molecule, bile acids can activate the relevant receptors to maintain the homeostasis of hepatic glucose and lipid metabolism, and interact with gut bacteria to ...
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Unlocking the Potential of α-Galactosidase
Introduction α-Galactosidase, a versatile enzyme, is gaining recognition for its pivotal role in various industries. In this article, we will delve deeper into the scientific underpinnings, applications, and benefits of α-Galactosidase. Our goal is to provide a detailed, informative exploration of this enzyme, grounded in scientific objectivity. α-Galactosidase: An Enzyme at ...
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IPEG 2023: Setting a Foundation for Healthcare Transformation
I recently had the pleasure of attending the IPEG annual meeting in Sorrento, Italy. The collegiality of the surgeons attending the conference was fantastic, and the views of Sorrento and the Island of Capri were stunning. With smaller accessible markets (due to smaller patient volumes and higher incidence of rare disease), specialty areas like pediatrics have been overlooked and under-addressed ...
By Caresyntax
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Understanding the Benefits of Probiotic Formula for Gut Health
The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will delve into the science behind probiotic formulas, exploring their mechanisms of ...
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Exploring the Multifaceted Applications of Ox Bile Extract Powder
Introduction: Ox bile extract powder, derived from ox bile, is a natural product with a wide range of applications. It contains essential components such as bile acids, cholesterol, bilirubin, and fatty acids. Through meticulous preparation processes, it is transformed into a powdered form, enhancing its stability and convenience. Ox bile extract powder exhibits diverse applications in the fields ...
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Label-based Protein Quantification Technology: iTRAQ, TMT, SILAC
Changes in the number of proteomes in a cell have a big effect on many aspects of life. For example, the occurrence and development of many diseases are often accompanied by abnormal expression of certain proteins. Quantitative proteomics is the accurate quantification and identification of all proteins expressed in a genome or all proteins in a complex mixed system. At present, quantitative ...
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The Relationship Between Enzyme Function and Health
In the early 20th century, humans discovered vitamins, and then trace elements and minerals. It was only in the mid-1980s that humans realized the importance of enzymes. Nobel Prize in Physiology and Medicine Arthur Kornberg said: "For our lives, we can no longer find other substances as important as enzymes in nature." Enzymes control the entire body, and when enzymes function abnormally is ...
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Types and Application Value of Enzyme Engineering
As a biocatalyst, enzyme has been widely used in various production fields of light industry. In recent decades, with the continuous technological breakthroughs in enzyme engineering, it has become more and more widely used in industry, agriculture, medicine and health, energy development and environmental engineering. Food processing applications The biggest use of enzymes in the food ...
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Top-Down Proteomics vs. Bottom-Up Proteomics
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. The Edman degradation of peptides is a revolutionary method to identify the main amino acid sequence of a peptide. In addition, the whole sequence of proteins can be determined by ...
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Introduction to Protein Digestion—In-Gel or In-Solution
The most common endoprotease used for protein digestion is serine protease trypsin, which produces peptides that are highly amenable to MS/MS analysis. Depending on the preceding workflow, the enzymatic digestion of proteins is performed either in-gel or in-solution. Generally, the in-gel digestion methodology has become routine for proteins separated by 2-D electrophoresis while in-solution ...
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Top-Down Proteomics vs. Bottom-Up Proteomics
Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. Edman degradation of peptide is a revolutionary method to identify the main amino acid sequence of peptide. In addition, the whole sequence of proteins can be determined by ...
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Introduction to Protein Digestion: In-Gel or In-Solution
Among the endoproteases used for protein digestion, serine protease trypsin is the most common one, as it generates peptides that are highly amenable to MS analysis. Depending on the preceding workflow, the enzymatic digestion of proteins is performed either in-gel or in-solution. Generally, the in-gel digestion methodology has become routine for proteins separated by 2-D electrophoresis while ...
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Transitioning to a single-use mindset, getting ahead of the curve
If single use devices are inevitable, the next step after “why” needs to be an understanding of “how” medtech companies and device makers can get on the right side of the movement. The move towards single use scopes and other medical devices had its start long before Covid-19, but the pandemic has accelerated this trend across the medical technology field. An emphasis ...
By Noah Medical
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Bacteria and Viruses: How They Differ
Bubonic plague, HIV/AIDS and COVID-19 are all examples of pandemics, however, the first is caused by bacteria and the other two are caused by viruses. Both viral and bacterial infections have similar effects on the body. Coughing, sneezing, fever, inflammation, vomiting, fatigue, and so forth are signs that your immune system is working to fight off an infection. While bacteria and viruses ...
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How the Gut Adapts in Short Bowel Syndrome Patients
Gut Adaptation; the body’s natural ability to “heal” itself. The human body is nothing short of miraculous. It can create life, perform incredible feats, and allow us to experience the world through a number of senses. But what happens when the body becomes damaged from illness or injury? Medical advancements have helped us come a long way in fighting disease, injury and ...
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How to Choose the Right Restriction Enzyme?
Restriction endonucleases are a class of enzymes that can recognize specific nucleotide sequences in double-stranded DNA molecules and cut phosphodiester bonds in DNA chains at specific positions. Different restriction endonucleases recognize different DNA sequences. They can cut DNA within the recognition sequence or at a position not far from the recognition sequence, and different types of ...
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What Are the Health Benefits of Probiotics?
Probiotics are a type of beneficial bacteria that exist in the human gut itself. There are more than 100 trillion bacteria in the human gut, which are roughly divided into beneficial bacteria, intermediate bacteria and harmful bacteria. When the human body is healthy, the intestinal flora is in a balanced state, but when you have symptoms of constipation and diarrhea, it means that the number of ...
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Three generations of ADC: Nearly a decade of development-PII
Kadcyla and second-generation non-cleavable linkers Alternative linker design methodologies are still under development. Immunogen discovered a very powerful ADC by an accidental discovery. The lysine residue of trastuzumab is linked to DM1 via a non-cleavable linker containing N-succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC), an ADC (T-DM1, Kadcyla) authorized by the FDA in ...
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Classification and Function of Lactic Acid Probiotics
Probiotics are a type of beneficial bacteria in the gut, and are now mostly used for gut conditioning and health care. However, people now know less about probiotics, and it is difficult for many people to distinguish whether probiotics are good or bad, and they do not know anything about probiotics. However, there are more than 400 types of probiotics in the human body, and the types of ...
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