Nephrology Articles
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Calcium Alginate Wound Dressings - Still Relevant Forty Years On!
SFM has been producing alginate products since the early 1980’s and still to this day alginates are an important product for our business. Alginate dressings are classed as ‘advanced wound care’, a label that up until now I have strongly disagreed with. How can a relatively simple dressing be thought of as ‘advanced’ in the current market? With newer ...
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Galectin 3 Inhibition Attenuates Renal Injury Progression in Cisplatin-Induced Nephrotoxicity
Annotations Kidney toxicity is a significant side-effect withGal-3 plays an essential role in kidney fibrosis and renal failure, and it is one of the critical factors for renal injury Inhibition of Gal-3, mediated by MCP, antagonized the pro-apoptotic (cell death) effects. MCP- treated mice demonstrated increased renal function and reduced renal fibrosis after cisplatin- induced MCP-treated ...
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3 Things That Google’s Healthcare Artificial Intelligence Desperately Needs
Google DeepMind recently published a paper in Nature that shared how their predictive algorithm can detect Acute Kidney Injury (AKI) up to 48 hours in advance. Acute Kidney Injury is the biggest problem you have never heard of. In the US, 1 in 5 hospitalized adults gets Acute Kidney Injury, resulting in a 5x risk of death. It takes the lives of over 300,000 Americans every year. Globally, the ...
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Biochemical and histopathological alterations in kidney of rats chronically exposed to mild silver protein
Chronic administration to Wistar rats of Mild Silver Protein (MSP) to a dose of 222 mg Ag/kg/day in the drinking water for six months showed that the MSP produces argyria, with histopathological lesions in the kidney, the organ where silver accumulates. The histopathology of the kidney showed capillary damage, with alteration of the vascular wall, increased perivascular cellularity and area with ...
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Functionalised carbon nanotubes: high biocompatibility with lack of toxicity
Recent studies from our laboratories have clearly shown the utility of the carbon nanotubes (CNTs) in biomedical applications. Therefore, the behaviour of CNTs following in vivo administration is of high interest. In this paper, we summarise some of our previously published results towards the assessment of the health impact of CNTs. We will initially describe the in vivo distribution of ...
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