Orthopedic Instruments Articles
-
Uses of Recombinant Human Collagen
Collagen is the main structural protein in vertebrates. It plays an essential role in providing a scaffold for cellular support and thereby affecting cell attachment, migration, proliferation, differentiation, and survival. Natural animal collagen and its recombinant collagen are favorable replacements in human tissue engineering due to their remarkable biomedical property. However, this ...
-
Unveiling The Manifold Potentials: Mesenchymal Stem Cells & Bone Marrow Mesenchymal Stem Cells
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
-
The Role of MMP-3: Insights into Disease Progression and Therapeutic Potential
The MMP Family Matrix metalloproteinases (MMPs) are a family of enzymes belonging to the metzincin superfamily. There are 23 different types of secreted or membrane-anchored endopeptidases in the human body. MMPs are capable of degrading ECM proteins such as collagen, gelatin, laminin, fibronectin, fibrinogen, elastin, and proteoglycans. They were once considered regulators of the extracellular ...
-
Meet Nuritas, the bitoech using AI to identify the next generation of intelligent ingredients
As part of our quick fire questions series – or QFQs – we spoke to Dr. Andy Franklyn-Miller, Chief Medical and Innovation Officer at Nuritas about intelligent ingredients, explaining peptides and proving an AI model in life science. There is a lack of innovation within ingredients in food, many have been discovered decades ago, mostly with cost, taste and texture in mind. However as ...
By Nuritas Ltd.
-
Powering Up Peptide Discovery with AI
Nuritas has recently published the results of two clinical studies on their next-generation ingredient PeptiStong™. Identified within fava beans, with self-affirmed GRAS and Health Canada approval, Peptistrong™ contains cell-signalling peptides which, when compared against milk proteins, were found to improve the rate of muscle protein synthesis during recovery. In this New Protein ...
By Nuritas Ltd.
-
Field Orthopaedics gets FDA approval for world’s smallest orthopaedic screw
The Brisbane-based designer of the world’s smallest orthopaedic screw has invoiced US hospital suppliers $900,000 in the three weeks since the device gained Food & Drug Administration approval, and he hopes it can soon be made in Brisbane too. Field Orthopaedics, founded in 2016 by former Army doctor Chris Jeffery alongside a team of doctors and engineers including hand surgeon Greg ...
-
Computer Vision for Medical and Healthcare Imaging Solutions
There are a ton of practical uses for computer vision at present times. One industry where this technology is increasingly useful in healthcare. It is impossible to exaggerate the value of computer vision services in the medical field. Its methods continue to be used more widely since they have demonstrated excellent utility in numerous medical contexts, including surgical planning and medical ...
-
Heal Your Torn ACL with the BEAR Implant
The anterior cruciate ligament, better known as the ACL, is one of the four ligaments within the knee that connect the femur to the tibia. It’s also one of the most commonly injured ligaments in the knee, especially among athletes. Unlike many other ligaments in the body, the ACL does not have the ability to heal on its own. A thick liquid – called synovial fluid – reduces ...
-
What are Surgical Options for ACL Tears?
The anterior cruciate ligament, better known as the ACL, is one of the two ligaments in the center of your knee that connect the femur to the tibia. It’s also one of the most commonly injured, especially among athletes. Unlike many other ligaments in the body, the ACL does not have the ability to heal on its own. A thick liquid – called synovial fluid – reduces friction ...
-
Huateng Pharma Develops Intermediates of Carfilzomib For Multiple Myeloma
Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...
-
A New Concept of Mosaicplasty: Autologous Osteoperiosteal Cylinder Graft Covered With Cellularized Scaffold
Abstract: A concern regarding osteochondral autograft transfer for chondral defects is donor-site morbidity of the knee, the most common source of the autograft. To avoid the drawbacks of osteochondral autograft transfer, a cylindrical osteoperiosteal graft harvested from the iliac crest covered by a same-sized cylinder of hyaluronic acidebased polymer scaffold pretreated with bone marrow ...
-
Surgeon Testimonials for the Archer CSR Total Shoulder System - Case Study
With the patient's humeral deformity, a stemmed humeral prosthesis would have been impossible," said Dr Wiater. Additionally, with the location of the deformity, a regular neck cut that is used with any other system would not have worked. We were fortunate to have Catayst's Archer CSR system for this ...
-
Surgeon Testimonials for the Archer CSR Total Shoulder System - Case Study
Below are several case studies and testimonials from actual surgeons performing total shoulder arthroplasties using the Archer™ CSR Total Shoulder System. The utilization of the anatomic Archer CSR humeral implant a/lowed for adequate bone stock retention to complete an anatomic transosseous supraspinatus repair and remove all of the patients painful pathology in one procedure. The patient ...
-
Surgeon Testimonials for the Archer CSR Total Shoulder System - Case Study
For this procedure I used Catalyst's Archer CSR system for a total shoulder arthroplasty using a lesser tuberosity osteotomy repair with a screw-and-suture technique. Post operatively this patient did very well. He had return of full range of motion at 12 weeks. He was able to return to all his activities, including sporting activities as well as lifting, pushing and ...
-
Programmed Drug Release of rhBMP-2 for Bone Healing
Summary: Non-union of bone fractures can cause pain and disabilities. Amongst certain fracture types, in specific age groups, the incidence of non-union is over 8% in the United States and over 3.6% of all fractures in the UK. Fracture non-unions have lifelong consequences and a debilitating impact in patients' life. Bone-grafts, allografts and xenograft are currently used to treat bone ...
-
How Much Do You Know about Glycosaminoglycans?
Glycosaminoglycan (GAG) is a general term for the glycan part of proteoglycan macromolecules. Glycosaminoglycans are large linear polysaccharides composed of repeating disaccharide units, and their main configuration contains amino sugars and uronic acids (glucuronic acid and/or iduronic acid). Glycosaminoglycans can be divided into chondroitin sulfate, dermatan sulfate, keratan sulfate, ...
By CD BioGlyco.
-
Rani is Opening Doors in Biosimilars, Challenging Humira and Others
San Jose-based Rani Therapeutics reported its fourth quarter and full-year 2021 financial results, as well as several corporate updates. The company hit major milestones this year, including the recent launch of the RaniPill High Capacity, which opens doors for significant developments in biosimilars. Rani has been on the radar of major life science investors for years. The company caught ...
-
Do You Really Know Hydroxyapatite?
As an important branch of biomedical materials, bioceramics are mainly used to manufacture hard tissue repair devices and artificial organs in vivo, and generally have good biocompatibility. According to the chemical activity in the physiological environment, bioceramics can be divided into three types: Nearly inert bioceramics, only weak or no chemical reaction occurs when exposed to the ...
By Matexcel
-
What Is Collagen?
Collagen is a family of proteins. At least 30 kinds of genes encoding collagen chains have been found, which can form more than 16 kinds of collagen molecules. According to its structure, it can be divided into fibrous collagen, basement membrane collagen, microfibrillar collagen, anchored collagen, hexagonal reticular collagen, non-fibrous collagen, transmembrane collagen, etc. According to ...
-
Diabetes: Medications, Treatments, and Remedies
Lifestyle can have a big impact on how your body handles blood glucose and sometimes a change in habits and activities is all that’s needed to prevent or better manage diabetes. But if changes in lifestyle aren’t enough to keep blood sugar levels normal, your doctor may prescribe medication to help lower insulin levels or insulin therapy. We’ll discuss here the most often ...
By Genteel LLC
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you