Prenatal Health Articles
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Maternal serum glycosylated fibronectin as a short-term predictor of preeclampsia: a prospective cohort study
Abstract Background: Preeclampsia is a major pregnancy complication that results in significant maternal and infant mortality, most of which occurs in low and middle-income countries. The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous ...
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Unveiling The Manifold Potentials: Mesenchymal Stem Cells & Bone Marrow Mesenchymal Stem Cells
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
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What are the Possibilities for ADCs Targeting Trop2?
Antibody drug conjugate (ADC) research involves more and more targets, such as HER-2, Trop-2, Claudin-18.2, B7-H3 and B7-H4, etc. Trop-2 is a transmembrane glycoprotein. Its high expression is associated with the occurrence of many tumors and poor prognosis. It is a very popular ADC research target, second only to HER2. Currently, only Gilead's Trop-2 ADC drug Trodelvy has been approved for ...
By BOC Sciences
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An Emerging Aim: ADC Target Protein - Nectin-4
The biologics license application (BLA) has been accepted for Enfortumab Vedotin for the treatment of locally advanced or metastatic urothelial carcinoma in patients who have previously received PD-1/PD-L1 inhibitors and platinum-containing chemotherapy. Enfortumab Vedotin is the first domestically submitted targeted antibody-drug conjugate that specifically targets Nectin-4. Enfortumab ...
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University College London Hospital, London, UK - Case Study
Introduction Incidence of caesarean section performed at full dilatation is increasing. Delivery can be technically challenging and associated with increased maternal and neonatal morbidity. The objectives of this study were to evaluate local caesarean section rate at full dilatation, assess the indications, review the maternal and neonatal morbidity and identify any training ...
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Understanding Lumbar Spinal Stenosis with Neurogenic Claudication
What is Lumbar Spinal Stenosis? Lumbar spinal stenosis, or LSS, is a common condition in which the lower spinal canal narrows and compresses the nerves in the lower back. Lumbar spinal stenosis is generally caused by aging and natural wear and tear on the spine. With lumbar spinal stenosis, thickened ligament, overgrowth of bone, and/or bulging discs in the lower back put pressure on the ...
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Preterm Birth and the Vaginal Microbiome
The vaginal microbiome has a profound impact on pregnancy health - here we dig into the science with an expert You might already be familiar with how the microbes that live in your vagina affect your health, especially when it comes to conditions like yeast infections or bacterial vaginosis (BV). But it’s not just about you - your vaginal microbiome (VMB) can also impact the outcome of ...
By Juno Bio
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World Immunization Week: Taming Latent Viruses for Longer Lives
The World Health Organization created World Immunization Week to highlight global collective action and promote the use of vaccines that keep all of us protected against disease. This year, the theme is “Long Life for All: In pursuit of a long life well lived.” The COVID-19 pandemic demonstrated the criticality of mRNA vaccines as a tool for quickly and effectively battling ...
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mRNA vaccine for the pregnant produces antibodies that are passed on to the child and remain for at least 6 months
As the COVID-19 pandemic enters its third year, efforts to mitigate the risk of infection remain critical, especially for vulnerable populations. Recently, Andrea Edlow et al. of Massachusetts General Hospital published a study in the journal JAMA entitled "Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection". The study showed that ...
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Clin.iobio Paper Published in Special Issue on Precision Medicine in Clinical Practice
Having recently published a paper on gene.iobio, we are excited to announce a publication describing the clin.iobio tool as part of the Journal of Personalized Medicine's Special Issue on Precision Medicine in Clinical Practice. Clin.iobio has been developed by the iobio team in Prof. Gabor Marth's lab at the University of Utah, with collaboration from Frameshift. Clin.iobio has been built to ...
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Maternal Mental Health Awareness During Pregnancy - Isabel Healthcare
Pregnancy is portrayed as a time of happiness and emotional well-being, and for many that is their experience, but evidence shows mental illness can affect women in pregnancy. Pregnancy impacts women from many angles with regards to their physical and mental health and also the baby’s health. There is much debate over whether you are more or less likely to have ill mental health during ...
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Module 3: Culture Medium
This is the third module in a four part series titled “Zero to One on the basic science behind cultivated meat”. You can click on these links to access: Course Overview, Module 1 (Cell Culture Basics), Module 2 (Cell Sources), Module 4 (Process monitoring). Learning objectives By the end of this module, you should understand: Basal culture medium composition and sources; ...
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UVision360, Inc. – Luminelle DTx Hysteroscopy System
Allison London Brown, CEO of UVision360, Inc. in North Carolina, discusses the Luminelle DTx Hysteroscopy System. Traditionally, these procedures are conducted in a hospital or ambulatory setting. But the Luminelle system is compact and designed to be used in the doctor’s office, and the company is expected to file an application with the FDA that will allow doctors to conduct the first ...
By LUMINELLE
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How Does Altis Biosystems Envision the Future of the Pharma/Biopharma Industry?
There is a growing need to address the high failure rate of drug candidates as they progress through clinical trials. Altis Biosystems aims to bring its technological advances to the forefront, enabling the drug development process to more effectively translate results from preclinical experiments to late-stage clinical trials. Breaking the Conformity of Inadequate Testing Platforms The ...
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FIGO good clinical practice paper: management of the second stage of labor
Abstract This good clinical practice paper provides an overview of the current evidence around second stage care, highlighting the challenges and the importance of maintaining high-quality, safe, and respectful care in all settings. It includes a series of recommendations based on best available evidence regarding length of second stage, judicious use of episiotomy, and the importance of ...
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University of Washington Medical Center - CDS-5 Cytogenetic Drying Chamber - Case Study
It’s not often you lovingly hug a 450-pound piece of equipment, but if it makes your work life easier you show your appreciation. The CDS-5 helps lab technologists create consistent and reliable environments for their work regardless of the day-to-day variables, like the weather. Imagine the weather outside impacting your office work indoors. Sounds inconvenient, right? That used to be a ...
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CBD: Perils, Promise and Development for Neuropathic Pain
Cannabidiol, or CBD, is one of several compounds extracted from the cannabis (marijuana) plant. In recent years, CBD has become enormously popular, and its market is believed to be hundreds of millions of dollars. Believers and users of CBD extoll its benefits for inflammation, muscle soreness, pain, anxiety and a whole host of other things, including cancer. It is, however, very understudied. ...
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UCT Clean Screen® DAU Cited in Umbilical Cord Drug Testing
Analysis of umbilical cord samples offers forensic toxicologists a method for evaluating maternal drug intake patterns. These matrices may be an uncommon sample for many laboratories, but for those that are tasked with the challenge, solid phase extraction offers the most efficient methodology for the analysis of said compounds. An estimated 5% of expectant mothers use illicit drugs during ...
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Chemicals hampering our ability to have children
If you’re of that age when everyone around you seems to be popping out a new edition to the family, you may also have noticed a disturbing trend; many young couples are also having difficulty conceiving. Yes, we are waiting longer to have children these days, but what if other factors are at work as well? What if the air we breathe and the chemicals we come into contact with every day are ...
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Hengsheng suministrará 90000 llantas para Audi el año que viene
Hengsheng Tire ha anunciado la firma del "Acuerdo sobre Tecnología de contrato" con China, Audi fue a principios de diciembre de 2007, para la producción del nuevo Audi A6L en Shenyang, el nuevo Audi A4 90.000 carga de ruedas llantas. Esta es una manera fácil de Hengsheng mercado de neumáticos en China, la rápida creación de imagen de marca, aumentar la ...
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