Vertebral Spine Articles
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Peptides for Osteoporosis Research
Introduction to OsteoporosisOsteoporosis is a systemic multi-causal skeletal disease that is prone to fractures due to changes in systemic bone mass and microstructure of bone tissue, resulting in increased bone fragility. Osteoporosis is a type of disease that is difficult to cure. According to the etiology, it can be divided into primary osteoporosis, secondary osteoporosis and idiopathic ...
By BOC Sciences
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Finite element modeling of the full lumbar spine with an intervertebral disc nucleus replacement device
Introduction Nucleus replacement technologies are a minimally invasive treatment for degenerative tSsc disease. Nucleus replacement may better restore the natural biomechanics of the spine compared to alternative treatments. Finite element (FE) modeling can be used to determine the biomechanics associated with nucleus replacement devices. A novel nucleus replacement device was ...
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Biomechanical Flexibility Testing of an in Situ-Cured Silicone-Based Disc Nucleus Prosthesis
A new intervertebral disc nucleus replacement device having three major features has been designed, comprising: 1) a peripheral textile band, 2) a silicone membrane filled with silicone that cures in situ forming an elastomeric implant and 3) an internal chamber that allows for deformation of the cured component (Figure 1). Samples of this device were subjected to biomechanical flexibility ...
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Finite Element Study of a Lumbar Intervertebral Disc Nucleus Replacement Device
Nucleus replacement technologies are a minimally invasive alternative to spinal fusion and total disc replacement that have the potential to reduce pain and restore motion for patients with degenerative disc disease. Finite element modeling can be used to determine the biomechanics associated with nucleus replacement technologies. The current study focuses on a new nucleus replacement device ...
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Biomechanical Evaluation of an In Situ Cured Silicone Rubber Nucleus Replacement Device
A new intervertebral disc nucleus replacement device having three major features has been designed, comprising: 1) a peripheral textile band, 2) a silicone membrane filled with silicone that cures in situ forming an elastomeric implant and 3) an internal chamber that allows for deformation of the cured component (Figure 1). Samples of this device were subjected to biomechanical flexibility ...
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Discovery of Pathways that Promote Remyelination
In the evolutionary history of vertebrates, the emergence of myelin has made the transmission of neural signals much faster, and if humans evolve like invertebrate squid, the vertebral diameter of humans may be thicker than that of giant red fir trees. Insulating myelin sheaths encapsulate nerve axons, thereby allowing rapid conduction of action potentials between neurons, and in addition, myelin ...
By Profacgen
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Proximal Femur Responses to Sequential Therapy With Abaloparatide Followed by Alendronate in Postmenopausal Women With Osteoporosis by 3D Modeling of Hip Dual-Energy X-Ray Absorptiometry (DXA)
ABSTRACT Previous subgroup analyses from the ACTIVE trial in women with postmenopausal osteoporosis (NCT01343004) using three-dimensional (3D)-processing of dual X-ray absorptiometry (DXA) scans indicated greater increases in total hip cortical volumetric bone mineral density (Ct.vBMD) and estimated indices of hip strength following 18 months of abaloparatide (ABL) versus placebo or ...
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Bioinspired Hydrogel To Improve The 3d Printability Of Mechanically Demanding Tissues Such As Intervertebral Disc
Researchers from Albert-Ludwigs-Universität Freiburg im Breisgau, Université Claude Bernard Lyon 1, Universidad Central “Marta Abreu” de Las Villas and Johannes Gutenberg-Universität Mainz developed a 3d printable, bioinspired hydrogel composed of two different biopolymers, chitosan and cellulose nanofibers, through an environmentally friendly process by avoiding both ...
By Regenhu
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Postoperative Spinal Instability at L3-4 Revealed by Upright Weight-Bearing MRI - Case Study
The patient was scanned in the FONAR Upright MRI in early 2002, one year after her spinal fusion. Both Upright and recumbent scans were performed on her in the multi-position FONAR Upright MRI. The recumbent MRI (left image) exhibited only a normal lumbar lordotic curve and a modest bulge of the L3-4 intervertebral disc, consistent with her prior recumbent MRI scan on a conventional MRI. The ...
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Tang Jing's Stand Up Reading Desk In
The recently broadcasted TV series "My First Half Life" believes that everyone has heard of it and Tang Jing's capable workplace hero image has also been well received by the audience. Baobao found that there is a frequently appearing item which is very practical, that is the stand up reading desk. Whether you are at the study in your home or at your desk in the office, you can use a stand up ...
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Combatting the Opioid Crisis with Cell Therapies for Chronic Back Pain
It’s no secret that opioid addiction is at an all-time high and represents a major public health threat. The CDC estimates that opioid addiction resulted in a record 72,000 drug overdose deaths in 2017 alone. What strikes me as one of the most tragic parts of this narrative is that so many of these deaths were people who became addicted to opioids after simply seeking relief ...
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Performance Tes-ng of an Injectable Silicone Rubber Based Nucleus Replacement Device
A novel intervertebral disc nucleus replacement device is comprised of an elas-c silicone membrane filled with liquid in situ curable silicone to form an elastomeric implant surrounding a central gas chamber that allows inward deforma-on of the cured component under load. Samples of this device were subjected to finite element analysis (FEA), digital pressure mapping and biomechanical flexibility ...
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