Neurology Articles
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The Health Effects of Probiotics on the Human Body
Probiotics are a type of active microorganisms that play a role by improving the balance of the host's intestinal microflora. They can produce definite health effects to improve the host's microecological balance and play a beneficial role. In 2001, the World Food and Agriculture Organization (FAO) and the World Health Organization (WHO) also defined probiotics as follows: Live bacteria that can ...
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Focal Molography, A Guide Inside Cellular Pathways
Focal Molography, a Guide Inside Cellular Pathways There are billions of cells in our bodies, each with their own characteristics and functions. To function together, cells need to communicate; during the evolution of multi-cellular organisms, cells have developed communication systems of exceptional complexity. These systems govern every level of communication, and together they dictate cell ...
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Rho kinase inhibition in Amyotrophic Lateral Sclerosis - Case Study
REAL is a phase 2a open-label study to assess preliminary safety, tolerability, and effect on clinical outcomes as well as neurodegeneration biomarkers of BRAVYL in patients with ALS. The study will enroll approximately 20 patients, all of whom will be treated with BRAVYL for 24 weeks. ...
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Project - Sublingual IL2 (BL SLIT I)
The aim of this project is to develop low dose IL-2 for treatment of early onset juvenile Type I diabetes. Low dose injectable IL-2 in animal models has been shown to restore the balance between regulatory and effector T cells and, in this way, can help to reverse autoimmunity and the development of type I diabetes. Looking ahead, we anticipate that having a suitable oral formulation of IL-2 to ...
By BioLingus AG
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Bioinformatics Workflow for Whole Genome Sequencing
Whole genome sequencing (WGS) has the capacity to greatly enhance genomic knowledge and understand mysteries of life by utilizing the most advanced genetic sequencing technologies. WGS can be used for variant calling, genome annotation, phylogenetic analysis, reference genome construction, and more. WGS tries to cover the whole genome, but actually covers 95% of the genome with technical ...
By CD Genomics
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Feature Signature Discovery for Autism Detection: An Automated Machine Learning Based Feature Ranking Framework - Case Study
Abstract Autism spectrum disorder is the most used umbrella term for a myriad of neuro-degenerative/developmental conditions typified by inappropriate social behavior, lack of communication/comprehension skills, and restricted mental and emotional maturity. The intriguing factor of this disorder is attributed to the fact that it can be detected only by close monitoring of developmental milestones ...
By JADBio
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Psylo Leverages CDD Vault to Ramp Up Psychedelic Drug Discovery - Case Study
Psychedelic plants and fungi have been used medicinally by indigenous populations over thousands of years. But while psychedelic drug research has witnessed a relative roller-coaster ride of effort since the mid-20th century, more recent interest in the use of psychedelics for treating mental health and psychiatric disorders has spurred a raft of clinical trials1 . Studies are now evaluating the ...
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SpinTech MRI Earns FDA 510(k) Clearance for Rapid, Quantitative Brain-Imaging Technology
The US Food and Drug Administration (FDA) has given 510(k) clearance to SpinTech MRI’s latest magnetic resonance imaging software device, STAGE (STrategically Acquired Gradient Echo), a post-processing software platform that enables comprehensive, quantitative brain imaging with enhanced visualization in significantly less time than conventional approaches. STAGE allows MRI ...
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The Future of Quantitative Susceptibility Mapping (QSM) in Clinical Applications
The use of Quantitative Susceptibility Mapping (QSM) is often viewed as incompatible with current standard radiology workflows. Some radiologists or departments may be unaware of its existence or purpose. Despite the skepticism surrounding its viability in a clinical setting, QSM shows great potential in a wide range of clinical applications, particularly for biomarker detection and ...
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Do you really have to sacrifice MRI image quality for speed?
To understand the significance of the SpinTech MRI STAGE software platform, it helps to begin by asking a question: Given that MRI is an incredibly powerful diagnostic tool for neurological diseases like Alzheimer’s, dementia, Parkinson’s and multiple sclerosis (MS), why have radiologists and neurologists had to choose between conducting faster MRI exams and obtaining higher-quality ...
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Exploring Amyotrophic Lateral Sclerosis (ALS) with PercayAI’s AI Tools
Welcome to our newest blog series where we investigate Amyotrophic Lateral Sclerosis (ALS) using our AI knowledge mapping tools. Check back for our next installment, in which we analyze transcriptomics from spinal cord samples collected from patients as well as a mouse model. In this post, we will continue to explore publicly available datasets surrounding Amyotrophic Lateral Sclerosis ...
By PercayAI
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Comparison of Flexible Silicone Bolus to 3D Printed Rigid Bolus - Case Study
This case study illustrates designing and fabricating silicone bolus using the Adaptiiv software solution. This flexible silicone bolus fabrication process was then compared to the fabrication process of a rigid 3D printed bolus to determine whether it yielded comparable or improved plan metrics for treating an inner canthus ...
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CanaQuest President Interviewed by the Wall Street Analyzer
The attached is the transcript of an interview conducted by the Wall Street Analyzer with Paul Ramsay, President of CanaQuest Medical Corp. and posted on the Wall Street Analyzer’s website on January 5, 2023. Additionally, the full interview can be listened to on the Wall Street Analyzer’s website - Canaquest Medical Corp (OTC: CANQF) | The Wall Street Analyzer Interview Notes: 1. ...
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Adenocarcinomas and Their Often Misleading Symptoms When Dyspepsia Is an Indication of Cancer - Case Study
Medical History Jane is a 40-year-old, married mother of two teenage boys. She teaches at the local elementary school and has been in good health for most of her life. She has no surgical history. Her most severe ailment up to this point has been the flu at age 27. Her students are first-graders; they are often difficult to control. She also experiences the normal stresses of raising ...
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Field Orthopaedics gets FDA approval for world’s smallest orthopaedic screw
The Brisbane-based designer of the world’s smallest orthopaedic screw has invoiced US hospital suppliers $900,000 in the three weeks since the device gained Food & Drug Administration approval, and he hopes it can soon be made in Brisbane too. Field Orthopaedics, founded in 2016 by former Army doctor Chris Jeffery alongside a team of doctors and engineers including hand surgeon Greg ...
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Applications of 16S/18S/ITS Amplicon Sequencing
16S/18S/ITS amplicon sequencing has now been a well-established method. Due to its low cost, shorter cycle and low quality requirement of the sample, 16S/18S/ITS amplicon sequencing is widely used in the study of microorganisms. 16S/18S/ITS amplicon sequencing reveals the species of microorganisms in environmental samples and their differences, relative abundance, population structure and ...
By CD Genomics
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The tiny grabber that plucks blood clots out of a vein (The Mail on Sunday)
Thousands of patients suffering from deep vein thrombosis (DVT) are set to benefit from a lifesaving procedure using a new blood clot grabbing device pioneered by NHS specialists. The treatment involves inserting a stent, a tiny, ball- shaped wire cage into a blocked vein. Once in position, the collapsible cage is expanded and ‘ catches’ the clot. When the device is pulled out, the ...
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FDA Approved ALK Inhibitors for ALK-Positive Non-Small Cell Lung Cancer
Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases. Statistics show that about 55% of ALK-positive advanced NSCLC patients will develop brain metastases during ...
By BOC Sciences
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Computer Vision for Medical and Healthcare Imaging Solutions
There are a ton of practical uses for computer vision at present times. One industry where this technology is increasingly useful in healthcare. It is impossible to exaggerate the value of computer vision services in the medical field. Its methods continue to be used more widely since they have demonstrated excellent utility in numerous medical contexts, including surgical planning and medical ...
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How Is Frontotemporal Dementia Different From Alzheimer`s?
People living with frontotemporal dementia, or FTD, are commonly misdiagnosed with psychiatric disorders or Alzheimer’s disease and other causes of dementia, such as Parkinson’s disease and vascular dementia. While frontotemporal dementia and Alzheimer’s disease can both cause dementia, there are distinct differences in impacted regions of the brain and, consequently, ...
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