Neurology Articles
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The Structure of Key Proteins in Parkinson`s Disease Solved
Australian researchers have recently solved a multi-year mystery about Parkinson's disease. They solved the structure of a key protein that is expected to rapidly treat this incurable disease. The findings appear in Nature. For the first time, the researchers took a "live" shot of a protein called PINK1. The findings explain how this protein is activated in cells, thereby initiating the ...
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New Drug Discovery Tool that Can Screen More Than 11 Billion Compounds Found
There are docking stations called receptors on the surface of our cells. Various compounds ranging from caffeine and dopamine to heroin, tetrahydrocannabinol (THC) and lysergic diethylamine (LSD) all bind to these receptors. Indeed, G protein-coupled receptors are the intended target of action for more than 30% of drugs currently on the market. But these drugs often also target unintended targets ...
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Science: Blocking fibrin holds promise for the treatment of periodontal disease
In a new study, researchers from the National Institute of Dental Craniofacial Research (NIDCR) have found that blocking the function of a coagulation protein prevents bone loss caused by periodontal (gingival) disease in mice. According to animal and human data, they found that the accumulation of this clotting protein called fibrin triggers an excessive immune response that damages the gingiva ...
By Matexcel
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Probiotics Have Many Benefits for the Human Body
Probiotics are active microorganisms that are beneficial to the human body. They promote nutrient absorption and maintain the health of the intestinal tract by regulating the balance of the intestinal flora. The human intestinal flora contains a large number of microorganisms, as many as hundreds of species. In addition to probiotics, there are other microorganisms, such as viruses, fungi, ...
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The Mode of Action of Basic Proteins Involved in Cancer and Alzheimer's Disease Found
These proteins belonging to the HAT family are essential for life because they transport amino acids to the cell membrane. Although members of the family are nearly identical, they selectively transport certain amino acids. This specificity determines their involvement in specific functions, such as cell growth or neuronal function, and consequently in related diseases, such as cancer or ...
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Addressing Medical Negligence: Is It More Common than We Think?
It may surprise you to learn that the third most common cause of death in the U.S. is reputed to be medical negligence. The figures vary on the actual average number of deaths due to medical negligence each year. A John Hopkins study put the number at approximately 250,000 but other sources suggest it’s over 400,000 cases annually. The situation is so dire that the doctors involved with ...
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High prevalence of psychological distress among healthcare workers during pandemic
Doctors more likely to experience depression while anxiety more common among Nurses A study by a team of researchers from the University of Wollongong (UOW), St George Hospital and the Illawarra Health and Medical Research Institute (IHMRI) has found a high prevalence of anxiety and depression among healthcare workers around the world during the COVID-19 pandemic. The researchers found that ...
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A disability isn’t always visible!
In recognition of the International Day of Persons with Disabilities, we hear from one of our #SEGreatPeople on their experience of life with a ...
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California Prop65 list
1. Tetrahydrocannabinol (THC) Tetrahydrocannabinol (THC) is an active ingredient in Nabiximols, a specific extract of Cannabis that was approved as a botanical drug in the United Kingdom since 2010 as a mouth spray for people with multiple sclerosis to reduce neuropathic pain, spasticity, overactive bladder, and other symptoms. Nabiximols (as Sativex) is available as a prescription drug in ...
By ComplianceXL
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Caregiver for a Person with Disabilities - Mike Establishes Disability & Accessibility Employee Group
At Schneider Electric, we promote and respect the rights of people with disabilities by raising awareness and tackling the stigma and stereotypes faced by people with disabilities. We foster equal treatment and equal opportunities for people with disabilities and are working to build an inclusive culture for all abilities. In recognition of the International Day of Persons with Disabilities, Mike ...
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Submit to Panthera Dental Directly
Until recently, when you submitted a case to Panthera Dental for a Obstructive Sleep Apnea Device, they would manufacture it and send it to one of their partner labs. This would delay the process and add other hurdles. You can now directly submit the cases through the meditlink portal. You must attach an Rx form and you must have an account with ...
By CAD-Ray
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Submitting Models for Panthera Obstructive Sleep Apnea Device
It is a good idea to attach support pins to your models so labs don’t lose the vertical dimension and the protrusive position you ...
By CAD-Ray
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Project - Porous Flexible Paving Used at Mercy for Grass Pave Fire Lane
Porous Flexible Paving for Grass Pave Fire Lane and Overflow Parking at Mercy Hospital Rehab Center using AirPave by AirField ...
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Nature: Structure-based classification of tauopathies
Abnormal accumulation of misfolded tau in filaments is characteristic of many neurodegenerative diseases—precisely for this reason, these neurodegenerative diseases are collectively referred to as tauopathy. The Michel Goedert team and the Sjors Scheres team at the Molecular Biology Laboratory of the Medical Research Council in Cambridge, UK, witnessed the use of cryo-EM to dissect tau ...
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New Findings about BRD4 Protein You May Want to Know
A new study clarifies how BRD4 (a protein that scientists have studied for many years) directs the spatial organization of DNA in the cell nucleus (a key function of stem cells to differentiate into muscle cells), which promotes the understanding of certain cancers and complex congenital diseases. Since the way DNA is folded is essential for gene regulation, this research not only has ...
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Food Sources and Effects of Carotenoids
Carotenoid structure and category The major carotenoids contain α-carotene, β-carotene, γ-carotene, lutein, zeaxanthin, β-cryptoxanthin, lycopene, etc. Among the three isomers of carotenoids, β-carotene has the highest content and γ-carotene the least. α, β, γ-carotene and β-cryptoxanthin can be decomposed to form vitamin A, while lutein, ...
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Human Microbiome Research Promotes Progress of Precision Medicine
A large part of bacterial, archaeal, viral, and fungal microbial taxa consists of the human microbiome. While many of these microorganisms are commensal, some are harmful to humans and many are symbiotic. Our livelihoods are strongly intertwined with the microbes we allocate our bodies with, regardless of whether their appearance is advantageous, insignificant, or harmful. Over the past few ...
By CD Genomics
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The Key to Successful Experiment: Enzymatic Catalysis
For scientists and researchers, in order to realize the design and development of new products such as drugs, the first step is to ensure the success of their experiments. Therefore, every chemical reaction in the experiment is of vital importance, and it only takes one wrong move to end in a total defeat. However, the chemical reaction is complicated, and the speed of interaction between ...
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Lipidomics in Microbial Research
Lipids are a class of metabolites with diverse chemical structures. More than just components of cell membranes and energy storage substances, lipids can perform a variety of important biological functions in life activities. The structural diversity of lipids endows them with a variety of important biological functions: (1) they constitute an important component of the cell membrane. Many ...
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The Reality and Future of Peptide Drugs
It has been said that the 21st century is the century of peptide drugs, and the fate of this substance, which lies between a large protein and a small molecule compound, is bound to be extraordinary. What are peptide drugs? Peptides are a class of compounds made up of amino acids linked by peptide bonds and are chemically active substances commonly found in living organisms. According to the ...
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