Neurology Articles
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Evaluation of Anti-Stroke Drugs
Stroke, also known as transient ischemic attack or cerebrovascular accident, is an acute brain disease. Usually, a sudden rupture of a blood vessel in the brain or a blockage of a blood vessel that prevents blood from flowing to the brain can cause damage to brain tissue, resulting in a stroke. Long-term strokes can lead to brain damage, disability and even death. The brain serves as a ...
By Protheragen
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Skull Double Wall Glass Cups
The skull double wall glass cups are made of high borosilicate glass, which has a crystal clear view and is very attractive. The realistic and detailed skull hangs inside the clear glass, making a lasting impression. Stylish and sophisticated double-glazed glass keeps coffee hot for longer. Model Number: YF-DGC007 Capacity: 25ml,85ml, 140ml, 210ml Color: Clear Material: Borosilicate Glass ...
By Yafu Glass
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Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns
Introduction The human body is a complex network of genes and proteins, each playing a crucial role in maintaining our health. One such gene, DNM1L, has garnered significant attention in recent years due to its vital functions and its association with various diseases. In this blog post, we will delve into the world of DNM1L, exploring its function, the diseases it is linked to, and the ...
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Hargreaves Test-A Brief Overview
The Hargreaves test is one of the classic experiments used to detect thermal pain responses in rodents. The test is commonly used to quantify the thermal threshold to radiation or infrared thermal stimulation in the hind paw of mice and rats. In the Hargreaves test, a radiant or infrared heat source is usually placed underneath the rodent and aimed at the plantar surface of the rodent's hind ...
By Protheragen
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Nanobodies Definition, Structure, Advantages and Applications
What is a Nanobody?Nanobodies are the smallest functional single-domain antibodies known to be able to stably bind to antigens, and have unique structural and functional advantages. The molecular weight of nanobodies is only 12-15 kDa, which retains the antigen binding ability of traditional antibodies. However, nanobodies have higher solubility and stability, and have unique advantages in ...
By BOC Sciences
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The Liposome-Based PROTAC Strategy
Proteolysis Targeting Chimeras (PROTACs) are a novel approach for degrading target proteins. Recently, a new split-and-mix PROTAC (SM-PROTAC) system based on liposome self-assembly, known as LipoSM-PROTAC, was reported in the Journal of the American Chemical Society. The LipoSM-PROTAC system exhibits selective degradation of target proteins, with folate serving as a key ligand. In this study, the ...
By BOC Sciences
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Preclinical Animal Models as A Resource to Explore Rare Diseases
Rare diseases, also known as orphan diseases, are a diverse group of disorders that affect a small percentage of the population. Due to their low prevalence and limited understanding, treating and finding cures for these conditions present significant challenges. However, preclinical animal models have emerged as invaluable resources for advancing research and unraveling the mysteries surrounding ...
By Protheragen
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CSX-1004: A Promising Canidate in the Fight Against the Fentanyl Crisis
The opioid crisis in the United States is a devastating public health issue, with over 70,000 overdose deaths annually, largely driven by the highly potent synthetic opioid fentanyl. The urgency to address this crisis has spurred the development of innovative therapies to prevent and reverse fentanyl overdoses. In this blog, we will explore the groundbreaking preclinical work on CSX-1004, a fully ...
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Best Wound Care Kits & Solutions for Seniors
Each wound tells a unique life story, whether it's from a sudden accident or a chronic condition. Wound care is important, especially for the elderly. Giving them only love and care is far from enough, but you also need to learn how to effectively manage different types of wounds. In this article, we will discuss the best senior wound care solutions, quality senior care products, and provide ...
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Speeding Up Healthcare Innovation Leveraging Cloud Technology
Over the past decade, cloud computing has undergone remarkable expansion. The collective revenue generated by AWS, Google Cloud, and Microsoft surged from $49 billion in 2018 to an astonishing $206 billion in 2022.[i] Projections from Future Market Insights indicate that the revenue from cloud services is poised to maintain an impressive average annual growth rate of 21%, reaching a staggering ...
By Caresyntax
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Senvok: Adventures Secured, Active Boys Thriving
Senvok's emergency wound closure device plays a crucial role in home first aid, ensuring that the daily exploration and adventures of your active boys are not only thrilling but also safe. Challenges of Family Adventures: In the dynamic household of an active boy, each day unfolds as an adventure. The morning sun awakens his curiosity, leading him to explore the backyard, aspire to be the ...
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CD Genomics Takes Genomic Research to New Heights with Ribo-seq Technology
CD Genomics, a well-established leader in transcriptome solutions, is pleased to announce the introduction of Ribosome Profiling technology. This innovative technique promises to provide valuable insights into gene expression, protein synthesis, and regulation, offering potential advancements in the field of RNA translation research. Ribo-seq is a cutting-edge high-resolution sequencing ...
By CD Genomics
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What Is Metabolomics?
Metabolism is the assembly of biochemical reactions in living organisms, the material basis for life maintenance of living organisms, and an important basis for the study of life activities. Metabolomics studies the endogenous metabolic activities of life under the influence of the internal and external environments, including the detection and analysis of metabolite types and quantities and ...
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Do Peptide Drugs Need Acylation Blocking at Nα?
The formation of 2,5-diketopiperazine (DKP) with a bicyclic structure is one of the most detrimental side reactions and degradation pathways affecting peptide synthesis. Despite its crucial role as a versatile building block in drug discovery, the formation of DKP reactions is highly undesirable in the production of peptide drugs. DKP formation can occur during the process of peptide drug ...
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Application of Capillary Electrophoresis Technology in Biopharmaceuticals
Capillary Electrophoresis (CE) is an analytical technique used in the development and quality control of protein drugs. From medium optimization, clone screening, formulation stability research and purification process monitoring, to protein characterization, related impurity detection, protein structure identification and protein drug product quality control, CE is required in all aspects of ...
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CPR Vs. AED Training: What’s The Difference?
Every second counts in any emergency, particularly those involving sudden cardiac events. Training in life-saving procedures becomes pivotal in ensuring that a victim has the best chance of survival. Two terms that often surface in discussions about cardiac emergencies are CPR vs. AED training. While both aim at preserving life during cardiac crises, they serve different functions and involve ...
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AED In The Workplace: 5 Reasons Why It Matters
The modern workplace is more than just a space to accomplish tasks; it’s a community where employees spend a significant portion of their lives. As such, ensuring the safety and well-being of everyone in this environment is paramount. One crucial aspect of workplace safety that is often overlooked is the presence of an Automated External Defibrillator or AED. AED in the workplace is more ...
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Unveiling The Manifold Potentials: Mesenchymal Stem Cells & Bone Marrow Mesenchymal Stem Cells
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
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Nano-Flow Cytometry: A Revolutionary Tool for Biomedical Research
Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, with high sensitivity and accuracy. This makes them ideal for detecting diseases at their earliest stages, when they are most treatable. How does ...
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Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon
What is CD73? CD73, also known as ecto-5′-nucleotidase, is a groundbreaking immunoinhibitory protein that assumes a pivotal role in tumor growth and metastasis. Its primary function revolves around converting extracellular ATP into immunosuppressive adenosine, working in tandem with CD39 within normal tissues to curtail excessive immune reactions. However, this mechanism is often hijacked ...
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