Neurology Articles
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Evaluation of Anti-Stroke Drugs
Stroke, also known as transient ischemic attack or cerebrovascular accident, is an acute brain disease. Usually, a sudden rupture of a blood vessel in the brain or a blockage of a blood vessel that prevents blood from flowing to the brain can cause damage to brain tissue, resulting in a stroke. Long-term strokes can lead to brain damage, disability and even death. The brain serves as a ...
By Protheragen
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Skull Double Wall Glass Cups
The skull double wall glass cups are made of high borosilicate glass, which has a crystal clear view and is very attractive. The realistic and detailed skull hangs inside the clear glass, making a lasting impression. Stylish and sophisticated double-glazed glass keeps coffee hot for longer. Model Number: YF-DGC007 Capacity: 25ml,85ml, 140ml, 210ml Color: Clear Material: Borosilicate Glass ...
By Yafu Glass
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Unveiling the Intricacies of DNM1L: Function, Associated Diseases, and Inheritance Patterns
Introduction The human body is a complex network of genes and proteins, each playing a crucial role in maintaining our health. One such gene, DNM1L, has garnered significant attention in recent years due to its vital functions and its association with various diseases. In this blog post, we will delve into the world of DNM1L, exploring its function, the diseases it is linked to, and the ...
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The Liposome-Based PROTAC Strategy
Proteolysis Targeting Chimeras (PROTACs) are a novel approach for degrading target proteins. Recently, a new split-and-mix PROTAC (SM-PROTAC) system based on liposome self-assembly, known as LipoSM-PROTAC, was reported in the Journal of the American Chemical Society. The LipoSM-PROTAC system exhibits selective degradation of target proteins, with folate serving as a key ligand. In this study, the ...
By BOC Sciences
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CD Genomics Takes Genomic Research to New Heights with Ribo-seq Technology
CD Genomics, a well-established leader in transcriptome solutions, is pleased to announce the introduction of Ribosome Profiling technology. This innovative technique promises to provide valuable insights into gene expression, protein synthesis, and regulation, offering potential advancements in the field of RNA translation research. Ribo-seq is a cutting-edge high-resolution sequencing ...
By CD Genomics
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Unveiling The Manifold Potentials: Mesenchymal Stem Cells & Bone Marrow Mesenchymal Stem Cells
In the vibrant realm of cellular biology and regenerative medicine, mesenchymal stem cells (MSCs) hold unparalleled potential for therapeutic applications. Particularly noteworthy are bone marrow mesenchymal stem cells (BM-MSCs), a subtype of MSCs. Their unique properties make them indispensable resources for developing ground-breaking solutions for various medical conditions. Mesenchymal stem ...
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Chimeric RNA and Sequencing Technologies: Advancing Detection and Research
What is Chimeric RNA? Chimeric RNA, also known as fusion RNA, refers to RNA molecules that are formed as a result of the fusion of two or more different RNA transcripts. Chimeric RNA, a unique class of RNA molecules formed through various molecular mechanisms, such as trans-splicing, read-through transcription, and fusion genes. These hybrid transcripts play a significant role in diverse ...
By CD Genomics
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The Role of Chx10 Neurons in Global Motor Arrest
A recent study by Goni-Erro et al (2023) in Nature Neuroscience has shed light on a fascinating phenomenon: the neural control of global motor arrest. From the cessation of goal-directed actions to a broader motor arrest in response to fear or environmental cues, this complex behavior involves an intricate set of neuronal pathways. This recent study reveals that the activation of ...
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Unlocking the Possibilities of Customized Ionic Channel Expression Systems
Ionic channels, which are proteins present in the membranes of all living cells, are gaining significant importance in the fields of bio-medicine and biotechnology. They are responsible for the transmission of signals across cell membranes and are instrumental in multiple biological processes. This raises the demand for a systematic mechanism that can control their expression. The customized ...
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Understanding Induced Pluripotent Stem Cell Differentiation and the Role of iPSC Differentiation Kits in Biological Research
Pluripotent stem cells — cells with the ability to differentiate into nearly any cell type in the body, constituting a significant potential for regenerative medicine. Among these, induced Pluripotent Stem Cells (iPSCs), in particular, have garnered substantial interest from the scientific community due to their ability to be produced from adult cells, eliminating the ethical quandaries ...
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Development of Gene Therapy Viral Vectors for Rare Diseases
In many cases, gene therapy requires a vector to deliver the gene therapy drug to the target cell. Viral vectors have been one of the most widely studied vectors due to their outstanding transduction efficiency and other significant advantages. Viral vector-based gene therapy has now achieved good clinical results. More than a dozen viral gene therapy products have been approved for the treatment ...
By Protheragen
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Alkaloids: Nature's Chemical Wonders
In the realm of organic chemistry, one class of compounds has captured the scientific community's attention for decades - alkaloids. These naturally occurring compounds are known for their diverse chemical structures and profound biological activities. Many alkaloids have been discovered and studied extensively over the years, with more than 20,000 known alkaloids identified to date. Alkaloids ...
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The Power of Combining Telemetry and Plethysmography
The study of respiratory function and control of breathing is vital for understanding various physiological and pathological conditions. In preclinical research, gaining accurate and reliable data is essential to make meaningful discoveries and develop potential therapies. Combining implantable telemetry with whole body plethysmography offers a powerful approach that provides researchers with an ...
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How To Use TCM Pain Relief Patch Correctly?
TCM(Traditional Chinese Medicine) pain relief patches have a very good effect on alleviating cancer pain. Note that the traditional Chinese medicine analgesic patch cannot treat cancer, but it has a very obvious pain relief effect on neuropathic pain, muscle pain, body organ pain, and Google pain caused by cancer. Some cancer patients may experience aggravated pain when they use traditional ...
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CADM: A New Generation of Tumor Suppressor Genes
About Tumor Suppressor Genes A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. It usually facilitates apoptosis. With its absence, the human body will be functioning without its “brake” of cell proliferation. Cells are potent to go under abnormal growth processes and finally lead to tumor/cancer. Here are some key ...
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New Approach to Successfully Purify and Characterize Human Neural Stem Cells
Human brain has approximately 171 billion cells, of which slightly more than half (approximately 86 billion) are nerve cells. These 86 billion nerve cells are a diverse cell population with hundreds of specialized types and functions, but all originate from three neural cell lineages--neurons, oligodendrocytes, and astrocytes. All three cell lineages originate from a pool of neural stem and ...
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Ion Channel Screening & Profiling: Unlocking a New Dimension in Drug Discovery
In the realm of drug discovery, researchers are constantly striving to unlock new possibilities for the treatment of diseases. One crucial aspect of this endeavor is the understanding and exploration of ion channels - integral membrane proteins that regulate the flow of ions across cell membranes. These channels play a fundamental role in numerous physiological processes and are essential targets ...
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Exploring the Origins and Categorization of Microneedles
Microneedles (MN) is a new type of physical permeability-enhancing technology. It consists of multiple micron-scale fine needle tips connected to the base in an array. The needle body is generally 10-2000 microns high and 10-50 microns wide. The length, size and shape of the microneedles can be individually designed according to the needs of the application. When the microneedle delivers the ...
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Respiration & Neural Dynamics in Odor Fear Learning
Timing is an essential aspect of learning and behavior, both in humans and animals. Understanding how organisms perceive and encode time intervals is crucial for comprehending various cognitive processes. In the context of associative learning, temporal relations between events play a significant role, and recent studies have shown that animals can rapidly acquire temporal information. However, ...
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Introduction of Plant Extract for Personal Care Industry
1 Active ingredients of plant extract 1.1 Alkaloid Alkaloid, or plant alkaloid, is a alkaline nitrogen-containing organic compound and it is an active ingredient in Chinese herbal medicine. It is colorless and odorless and generally insoluble in water. 1.2 Flavonoid Flavonoid is widely found in various parts of plants, especially flowers and leaves. It has a variety of biological activities ...
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