ABK Biomedical Announces First Patient Treated in First-in-Human Clinical Study with Eye90 microspheres™ for treatment of liver tumors

ABK Biomedical, Inc., an innovative, clinical-stage medical device company dedicated to the research, development and commercialization of advanced imageable embolic therapies, announced the first patient treated in ABK’s First-in-Human study with Eye90 microspheres™, a Y90 radioembolization device for the treatment of liver cancers. This study is being conducted in collaboration with Auckland Hospital Research Unit, New Zealand.

The prospective, single-center, open-label study is evaluating the safety and effectiveness of Eye90 microspheres in patients with unresectable hepatocellular carcinoma (HCC) or metastatic colorectal cancer (mCRC). Patients will receive a single Eye90 microspheres radioembolization treatment with follow-up visits for one year to assess safety, effectiveness, and quality of life measures.

Eye90 microspheres are radiopaque glass microspheres visible on x-ray and Computed Tomography (CT) imaging and contain the Yttrium 90 (Y90) radiotherapeutic element. Y90 radioembolization, a local brachytherapy, is currently used to treat malignant liver tumors. Primary liver cancer is the sixth most diagnosed cancer and the third leading cause of cancer death worldwide, with approximately 906,000 new cases annually. HCC is the most common primary liver cancer comprising 75%-85% of all primary liver cancer cases 1 with the majority of patients diagnosed with unresectable disease. Colorectal cancer (CRC) is the third most diagnosed cancer2, approximately 22% of CRCs present as mCRC at initial diagnosis, and about 70% of patients will eventually develop metastatic relapse.3

About ABK Biomedical Inc.

ABK Biomedical is focused on researching, developing, and commercializing breakthrough medical device therapies to improve treatment outcomes and the lives of patients with benign and malignant hypervascular tumors. ABK Biomedical holds intellectual property in the areas of inorganic polymer microspheres, and unique administration systems. The company possesses advanced intellectual capital and its own R&D and manufacturing facilities for developing and commercializing unique embolotherapy products. ABK Biomedical Inc. products are considered investigational products and are NOT approved for use in any regulatory jurisdiction outside of approved clinical trials.