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Chronic Autoimmune Disease Articles & Analysis

26 news found

Neutrophils and Lactoferrin a key duo in inflammation

Neutrophils and Lactoferrin a key duo in inflammation

This limitation has made it difficult to fully grasp their contribution to health and disease. Recent scientific progress is now changing this picture. Researchers have developed innovative ways to study neutrophils by focusing on one of their most important components: lactoferrin. ...

ByBertin Technologies


The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils, Halts Cancer Progression and Metastasis

The Wistar Institute and Jubilant Therapeutics Inc. Find PAD4 Inhibition in Neutrophils, Halts Cancer Progression and Metastasis

“These results highlight the potential of PAD4 inhibition as a novel treatment approach for cancer in addition to the previously established role of this pathway in autoimmune diseases," said Luca Rastelli, Ph.D., Chief Scientific Officer, Jubilant Therapeutics Inc. "We are developing several highly selective oral, small molecule PAD4 inhibitors, with the ...

ByJubilant Therapeutics Inc.


Gesynta Pharma completes patient enrollment in its Phase II study in systemic sclerosis

Gesynta Pharma completes patient enrollment in its Phase II study in systemic sclerosis

Systemic sclerosis (also known as scleroderma) is a chronic, autoimmune disease that leads to serious damage to the microvessels. Already in the first stages of the disease, patients are affected by episodes of reduced blood flow in fingers and toes. ...

ByGesynta Pharma AB


ANGANY Gaining Momentum for Plant-Based Immunotherapy Platform

ANGANY Gaining Momentum for Plant-Based Immunotherapy Platform

Besides their allergy program, ANGANY is also working in developing other immunotherapy applications including degenerative disease and oncology for both human and veterinary indications. As previously reported by IHS (November 24th, 2021) ANGANY entered a partnership with Nextmune (Vimian Group) for the development of their first product candidates for veterinary use in Canine ...

ByAngany Inc.


Aurinia Presents Data Demonstrating LUPKYNIS (voclosporin) is Effective in Achieving Proteinuria Treatment Targets in Lupus Nephritis Defined by EULAR/ERA Recommendations

Aurinia Presents Data Demonstrating LUPKYNIS (voclosporin) is Effective in Achieving Proteinuria Treatment Targets in Lupus Nephritis Defined by EULAR/ERA Recommendations

(NASDAQ:AUPH) (Aurinia or the Company), a biopharmaceutical company committed to delivering therapeutics that change the course of autoimmune disease, presented data demonstrating the efficacy of LUPKYNIS® (voclosporin) for the treatment of people with lupus nephritis (LN), a serious complication of systemic lupus erythematosus (SLE), in achieving the ...

ByAurinia Pharmaceuticals Inc.


Aurinia Presents Results from the Two-Year AURORA 2 Continuation Study at the 2022 European Renal Association (ERA) Congress

Aurinia Presents Results from the Two-Year AURORA 2 Continuation Study at the 2022 European Renal Association (ERA) Congress

(NASDAQ:AUPH) (Aurinia or the Company), a biopharmaceutical company committed to delivering therapeutics that change the course of autoimmune disease, today presented for the first time the results of the AURORA 2 continuation study evaluating the long-term safety and tolerability of LUPKYNIS™ (voclosporin) for the treatment of adults with active lupus ...

ByAurinia Pharmaceuticals Inc.


Kadimastem Expands R&D Program to Include Multiple Sclerosis

Kadimastem Expands R&D Program to Include Multiple Sclerosis

"We are very excited about the expansion of the range of neurological diseases that astrocyte cells (AstroRx®) could be used to treat. The pre-clinical study that will be conducted at Professor Ben-Hur's laboratory is extraordinary. ...

ByKadimastem Ltd.


Aurinia Pharmaceuticals Announces Presentations at the 2022 ERA Congress and the 2022 EULAR Congress

Aurinia Pharmaceuticals Announces Presentations at the 2022 ERA Congress and the 2022 EULAR Congress

(NASDAQ:AUPH) (Aurinia or the Company), a biopharmaceutical company committed to delivering therapeutics that change the course of autoimmune disease, today announced that data from multiple studies of LUPKYNIS™ (voclosporin) will be presented at the 59th European Renal Association (ERA) Congress and at the European Congress of Rheumatology, European ...

ByAurinia Pharmaceuticals Inc.


Gesynta Pharma`s drug candidate GS-248 granted Orphan Drug Designation in US by the FDA for the treatment of systemic sclerosis

Gesynta Pharma`s drug candidate GS-248 granted Orphan Drug Designation in US by the FDA for the treatment of systemic sclerosis

Systemic sclerosis (also known as scleroderma) is a chronic, autoimmune disease that affects, among other things, the body's smallest vessels, the microvasculature, and is associated with great medical needs due to the current lack of safe and effective medicines. ...

ByGesynta Pharma AB


Aurinia Announces Year-Two Commitment to Patient Navigation Grant Program to Address Barriers for Individuals Living with Lupus and Lupus Nephritis

Aurinia Announces Year-Two Commitment to Patient Navigation Grant Program to Address Barriers for Individuals Living with Lupus and Lupus Nephritis

“The results from the first year of patient navigation grants illustrate the measurable impact these programs can have on improving diagnosis and disease management and supporting better adherence to medical appointments and treatments,” said Jessica Bateman, Advocacy Relations, Aurinia Pharmaceuticals. ...

ByAurinia Pharmaceuticals Inc.


Aurinia Pharmaceuticals Announces Presentations at the 2022 National Kidney Foundation Spring Clinical Meetings

Aurinia Pharmaceuticals Announces Presentations at the 2022 National Kidney Foundation Spring Clinical Meetings

(NASDAQ: AUPH) (Aurinia or the Company), a biopharmaceutical company committed to delivering therapeutics that change the course of autoimmune disease, today announced that data from multiple studies of LUPKYNIS™ (voclosporin) will be presented at the 2022 National Kidney Foundation Spring Clinical Meetings, taking place April 6-10, 2022 in Boston, Mass. ...

ByAurinia Pharmaceuticals Inc.


Aurinia Announces Positive Topline Results From the AURORA 2 Continuation Study of LUPKYNIS (voclosporin) for the Treatment of Adults With Active Lupus Nephritis (LN)

Aurinia Announces Positive Topline Results From the AURORA 2 Continuation Study of LUPKYNIS (voclosporin) for the Treatment of Adults With Active Lupus Nephritis (LN)

(NASDAQ:AUPH) (Aurinia or the Company), a biopharmaceutical company committed to delivering therapeutics that change the course of autoimmune disease, today announced positive topline results from the AURORA 2 continuation study evaluating the long-term safety and tolerability of LUPKYNIS™ (voclosporin) for the treatment of adults with active lupus ...

ByAurinia Pharmaceuticals Inc.


SetPoint Medical Appoints Amy Derosier as Vice President of Clinical Affairs

SetPoint Medical Appoints Amy Derosier as Vice President of Clinical Affairs

SetPoint Medical, a clinical-stage bioelectronic medicine company developing therapies for chronic autoimmune diseases, today announced the appointment of Amy Derosier as Vice President of Clinical Affairs. ...

BySetpoint Medical Corporation


Aurinia Announces Updated Interim Results from the AURORA 2 Continuation Study of LUPKYNIS (voclosporin) for the Treatment of Lupus Nephritis

Aurinia Announces Updated Interim Results from the AURORA 2 Continuation Study of LUPKYNIS (voclosporin) for the Treatment of Lupus Nephritis

(NASDAQ: AUPH) (Aurinia or the Company), a biopharma company committed to delivering therapeutics that change the course of autoimmune disease, today announced updated interim results from the AURORA 2 continuation study evaluating the long-term safety and tolerability of LUPKYNIS™ (voclosporin) for the treatment of lupus nephritis (LN) in patients with ...

ByAurinia Pharmaceuticals Inc.


Accelerating Lupus Drug Discovery & Development - Fireside Chat with Experts in SLE Research

Accelerating Lupus Drug Discovery & Development - Fireside Chat with Experts in SLE Research

Genuity Science is bringing together a distinguished panel of experts from academia, research and industry to discuss opportunities and advancements in developing better treatments for systemic lupus erythematosus (SLE). SLE is a chronic and relapsing autoimmune disease characterized by a break-down of self-tolerance that leads to tissue ...

ByGenuity Science


Runway Growth Capital Announces a Senior Secured Term Loan of $35 Million to SetPoint Medical

Runway Growth Capital Announces a Senior Secured Term Loan of $35 Million to SetPoint Medical

Founded in 2007, SetPoint is dedicated to developing technologies to treat patients with chronic autoimmune diseases. The company is pioneering a new treatment paradigm, using electrical pulses that activate the body’s innate “inflammatory reflex,” for rheumatoid arthritis (RA), Crohn’s disease and other ...

BySetpoint Medical Corporation


Phase II update: Gesynta Pharma announces significant progress across development program for first-in-class drug candidate GS-248

Phase II update: Gesynta Pharma announces significant progress across development program for first-in-class drug candidate GS-248

Coordinating Investigator Professor Ariane Herrick, The University of Manchester Centre for Musculoskeletal Research commented: "Systemic sclerosis is a chronic, autoimmune disease that leads to serious damage to the microvessels and which is associated with great unmet need. ...

ByGesynta Pharma AB


SetPoint Medical CEO Murthy Simhambhatla Named to AIMBE College of Fellows

SetPoint Medical CEO Murthy Simhambhatla Named to AIMBE College of Fellows

SetPoint Medical, a clinical-stage bioelectronic medicine company developing therapy for chronic autoimmune diseases, today announced that the American Institute for Biological and Medical Engineering (AIMBE) has elected Murthy Simhambhatla, PhD, to the AIMBE College of Fellows for “outstanding contributions as a medical technology ...

BySetpoint Medical Corporation


Actym Therapeutics Announces Expansion of Scientific Advisory Board

Actym Therapeutics Announces Expansion of Scientific Advisory Board

During his 20 years in the pharmaceutical and biotech industry, he has led numerous drug development programs from discovery through early clinical stage, with a focus on therapies for cancer, chronic viral, autoimmune and inflammatory diseases, including overseeing development of the immunomodulatory anti-PD-1 monoclonal antibody Keytruda, and ...

ByActym Therapeutics


SetPoint Medical Receives FDA Breakthrough Device Designation for its Novel Bioelectronic Platform

SetPoint Medical Receives FDA Breakthrough Device Designation for its Novel Bioelectronic Platform

The Company is developing its platform for the treatment of chronic, inflammation-mediated autoimmune diseases, and is initially focused on the treatment of RA as a potentially efficacious, yet less immunosuppressive option. ...

BySetpoint Medical Corporation

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