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Clinical Supply Articles & Analysis: Older

31 news found

Combines mesenchymal stem-cell-based product, with Kurve’s intranasal drug delivery technology

Combines mesenchymal stem-cell-based product, with Kurve’s intranasal drug delivery technology

The production is performed at the hospital utilizing the Orgenesis Mobile Processing Units and Lab (OMPUL) to supply clinical grade batches. Glioblastoma Multiforme (GBM) is a highly aggressive cancer with an estimated five-year survival rate of 5%. ...

ByKurve Therapeutics, Inc.


Carrick Therapeutics and The Menarini Group Announce Clinical Trial Collaboration to Evaluate Samuraciclib and Elacestrant Combination

Carrick Therapeutics and The Menarini Group Announce Clinical Trial Collaboration to Evaluate Samuraciclib and Elacestrant Combination

Carrick Therapeutics, an oncology-focused biopharmaceutical company discovering and developing highly differentiated therapies, and the Menarini Group ("Menarini"), a privately-held, leading international pharmaceutical company, today announced a clinical trial collaboration and supply agreement. This agreement covers the execution of a Phase 2 ...

ByThe Menarini Group


Immune-Onc Therapeutics Initiates Expansion Cohorts for IO-108 and Enters into Clinical Supply Agreement with Regeneron

Immune-Onc Therapeutics Initiates Expansion Cohorts for IO-108 and Enters into Clinical Supply Agreement with Regeneron

IO-108 is being studied as a monotherapy and in combination with select anti-PD-1 antibodies in multiple expansion cohorts of solid tumors Clinical supply agreement with Regeneron accelerates Immune-Onc’s solid tumor clinical development program Immune-Onc Therapeutics, Inc. ...

ByImmune-Onc Therapeutics, Inc.


Greenwich LifeSciences Provides Updates on Flamingo-01 Phase III Clinical Trial

Greenwich LifeSciences Provides Updates on Flamingo-01 Phase III Clinical Trial

Clinical site initiation visits to train clinicians, nurses, coordinators, and pharmacists are underway, after which sites will be activated and the Flamingo-01 Phase III clinical trial will commence. ...

ByGreenwich LifeSciences, Inc.


BriaCell Partners with Waisman Biomanufacturing to Manufacture and Supply Prostate Cancer Immunotherapy

BriaCell Partners with Waisman Biomanufacturing to Manufacture and Supply Prostate Cancer Immunotherapy

Waisman Biomanufacturing has entered an agreement with BriaCell to manufacture clinical supplies for BriaCell’s anticipated clinical trial in advanced prostate cancer. ...

ByBriaCell Therapeutics Corp.


Charles River and Ziphius Vaccines Collaborate to Manufacture saRNA-Based Vaccine

Charles River and Ziphius Vaccines Collaborate to Manufacture saRNA-Based Vaccine

Utilizing its custom HQ plasmid offering which, being manufactured to the principles of GMP, serves as a phase-appropriate solution for early clinical trials, Ziphius Vaccines will benefit from accelerated timelines without compromising on quality. Charles River, with the acquisitions of Cognate BioServices, Cobra Biologics, and Vigene Biosciences in 2021, has expanded its ...

ByZiphius Vaccines NV


Carina Biotech appoints Cell Therapies to undertake manufacture of LGR5 CAR-T cells for clinical trial

Carina Biotech appoints Cell Therapies to undertake manufacture of LGR5 CAR-T cells for clinical trial

Our LGR5 CAR-T cell has continued to deliver impressive results in pre-clinical testing. We submitted our pre-IND application in March this year and we are on track to file an IND application with the FDA in the second half of 2022. ...

ByCarina Biotech


Vaxxas and University of Sydney complete study assessing needle-free HD-MAP technology for vaccine administration

Vaxxas and University of Sydney complete study assessing needle-free HD-MAP technology for vaccine administration

The goal was to ascertain whether professional immunisers and healthcare workers found the clinical HD-MAP applicator usable and acceptable for vaccine delivery. Findings of the study were published in the Journal of Human Vaccines and Immunotherapeutics on 31 January 2022 in a paper titled, Usability, acceptability, and feasibility of a High-Density Microarray Patch (HD-MAP) ...

ByVaxxas, Inc.


Matica Bio Opens New Cell & Gene Therapy GMP Facility in Texas

Matica Bio Opens New Cell & Gene Therapy GMP Facility in Texas

“Our new facility is designed for rapid development, scale-up and production for clinical supply, but our experienced teams provide quality oversight and regulatory guidance necessary to ensure success. ...

ByMatica Biotechnology, Inc.


Senseonics Holdings, Inc. Reports Fourth Quarter and Full Year 2021 Financial Results

Senseonics Holdings, Inc. Reports Fourth Quarter and Full Year 2021 Financial Results

The increase was due to the expansion of the R&D workforce, and an increase in clinical studies, lab supplies, and contractor expenses. Net income was $84.4 million, or $0.19 per share, in the fourth quarter of 2021, compared to a net loss of $101.6 million, or ($0.41) per share, in the fourth quarter of 2020. ...

BySenseonics


NiKang Therapeutics and AVEO Oncology Announce a Clinical Trial Collaboration and Supply Agreement to Evaluate the Combination of NKT2152, a HIF2a Inhibitor, and FOTIVDA® (tivozanib) for the Treatment of Advanced Clear Cell Renal Cell Carcinoma

NiKang Therapeutics and AVEO Oncology Announce a Clinical Trial Collaboration and Supply Agreement to Evaluate the Combination of NKT2152, a HIF2a Inhibitor, and FOTIVDA® (tivozanib) for the Treatment of Advanced Clear Cell Renal Cell Carcinoma

NiKang Therapeutics Inc. (“NiKang”), a clinical stage biotech company focused on developing innovative small molecule oncology medicines to help patients with unmet medical needs and AVEO Oncology (Nasdaq: AVEO), a commercial stage, oncology-focused biopharmaceutical company (“AVEO”) , today announced that they have entered into a clinical ...

ByAVEO Pharmaceuticals, Inc.


AVEO Oncology Announces Clinical Trial Collaboration and Supply Agreement with Merck KGaA, Darmstadt, Germany to Evaluate Ficlatuzumab and ERBITUX® (cetuximab) in Patients with Recurrent or Metastatic HNSCC

AVEO Oncology Announces Clinical Trial Collaboration and Supply Agreement with Merck KGaA, Darmstadt, Germany to Evaluate Ficlatuzumab and ERBITUX® (cetuximab) in Patients with Recurrent or Metastatic HNSCC

AVEO Oncology (Nasdaq: AVEO), a commercial stage, oncology-focused biopharmaceutical company, today announced that it has entered into a clinical trial collaboration and supply agreement with Merck KGaA, Darmstadt, Germany to evaluate ficlatuzumab in combination with ERBITUX® (cetuximab), an EGFR-targeted antibody, in patients with recurrent or metastatic ...

ByAVEO Pharmaceuticals, Inc.


AVEO Oncology Highlights Recent Progress and 2022 Outlook

AVEO Oncology Highlights Recent Progress and 2022 Outlook

For tivozanib, these milestones include initiation and continued enrollment of the Phase 3 TiNivo-2 clinical trial in advanced refractory RCC, and the presentation of data for the first-line cohort of the Phase 1b/2 DEDUCTIVE clinical trial in unresectable locally advanced or metastatic hepatocellular carcinoma (HCC) at American Society of ...

ByAVEO Pharmaceuticals, Inc.


GI Innovation enters into clinical collaboration with AstraZeneca to explore Immuno-oncology GI-101 • Imfinzi® Combination Therapy

GI Innovation enters into clinical collaboration with AstraZeneca to explore Immuno-oncology GI-101 • Imfinzi® Combination Therapy

GI Innovation, Inc., (CEO, Jun Ho Hong) announced that GI Innovation signed a clinical supply collaboration agreement with global biopharmaceutical company AstraZeneca for development of GI-101 and Imfinzi® combination therapy. ...

ByGI Innovation


GI Innovation signed a contract with Medirama for joint research development of next generation innovative immuno-oncology

GI Innovation signed a contract with Medirama for joint research development of next generation innovative immuno-oncology

GI Innovation licensed out main pipeline, immuno-oncology GI-101 (Simcere China) and allergic disease treatment GI-301 (Yuhan Pharm.) in non-clinical stage value of 2.3 trillion won and currently each pipeline is progressing global clinical 1/2 phase and domestic clinical 1 phase. In particular, GI Innovation recently unveiled the progress of ...

ByGI Innovation


Evaxion Biotech Announces Q3 2021 Financial Results and Provides Business Update

Evaxion Biotech Announces Q3 2021 Financial Results and Provides Business Update

We plan to initiate a Phase 2b clinical trial for EVX-01 in melanoma by the end of 2021 in collaboration with Merck and initiate a Phase 2b clinical trial of EVX-02, in conjunction with our third product candidate, EVX-03, in Q2 2022. ...

ByEvaxion Biotech A/S


Thermo Fisher Scientific Showcases Investment and Innovation During CPhI Worldwide 2021

Thermo Fisher Scientific Showcases Investment and Innovation During CPhI Worldwide 2021

Through its acquisition of Henogen, Novasep's viral vector business, the company added more than 75,000 square feet of clinical and commercial manufacturing capacity with two locations in Seneffe and Gosselies, Belgium. As part of its strategic collaboration with the University of California, San Francisco (UCSF), Thermo Fisher has begun construction on a state-of-the-art cell ...

ByThermo Fisher Scientific


Matica Bio Announces Joint Research Agreement with Sartorius for the Development of Advanced Viral Vector Manufacturing Technology

Matica Bio Announces Joint Research Agreement with Sartorius for the Development of Advanced Viral Vector Manufacturing Technology

Matica Biotechnology, Inc, (Matica Bio) a contract development and manufacturing organization (CDMO) specializing in the clinical and commercial production of cell and gene therapies, today announced a joint research agreement (JRA) with Sartorius, a leading international partner of the biopharmaceutical industry. ...

ByMatica Biotechnology, Inc.


Endpoint Clinical and Berlinger Collaborate to Provide Complete Visibility of the Historical Temperature Journey of an IMP

Endpoint Clinical and Berlinger Collaborate to Provide Complete Visibility of the Historical Temperature Journey of an IMP

Endpoint Clinical, the leader in global interactive response technology (IRT®) for clinical trials, and Berlinger & Co. ...

ByEndpoint Clinical


endpoint and THREAD Simplify DCT Operations for Key Stakeholders to Reduce Study Timelines

endpoint and THREAD Simplify DCT Operations for Key Stakeholders to Reduce Study Timelines

endpoint Clinical, the leader in global interactive response technology (IRT®) for clinical trials, and THREAD, a leading technology and service provider enabling decentralized clinical trials (DCT), have announced their partnership to offer sponsors and sites a solution that simplifies DCT operations and reduces research study timelines. ...

ByEndpoint Clinical

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