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Coronary Artery Bypass Grafts Articles & Analysis

23 news found

XyloCor Therapeutics Commences Phase 2 Component of Phase 1/2 EXACT Clinical Study of XC001 Gene Therapy for Refractory Angina

XyloCor Therapeutics Commences Phase 2 Component of Phase 1/2 EXACT Clinical Study of XC001 Gene Therapy for Refractory Angina

Food and Drug Administration (FDA) for XC001 as adjunctive therapy to coronary artery bypass grafting (CABG) in 2H21. The company also plans other clinical studies in additional cardiovascular indications, including heart failure caused by ischemic heart disease and as adjunctive therapy to percutaneous coronary ...

ByXyloCor Therapeutics


XyloCor Therapeutics Achieves Target Enrollment in Phase 2 EXACT Study of XC001 Novel Gene Therapy for Ischemic Heart Disease

XyloCor Therapeutics Achieves Target Enrollment in Phase 2 EXACT Study of XC001 Novel Gene Therapy for Ischemic Heart Disease

About the EXACT Study The Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (EXACT) clinical trial is a Phase 1/2 multicenter, open-label, single-arm trial. ...

ByXyloCor Therapeutics


XyloCor Therapeutics Announces Presentation of Preliminary Clinical Data from Phase 1 Portion of the EXACT Phase 1/2 Study of XC001 Novel Gene Therapy for Refractory Angina at AATS and ASGCT

XyloCor Therapeutics Announces Presentation of Preliminary Clinical Data from Phase 1 Portion of the EXACT Phase 1/2 Study of XC001 Novel Gene Therapy for Refractory Angina at AATS and ASGCT

About the EXACT Study The Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (EXACT) clinical trial is a Phase 1/2 multicenter, open-label, single-arm trial. ...

ByXyloCor Therapeutics


Xeltis accelerating clinical trial program

Xeltis accelerating clinical trial program

Xeltis currently has three restorative devices in clinical trial phase, including aXess – a restorative access graft for dialysis; XABG – which is a coronary artery bypass graft; and its pulmonary heart valve, which was the first ever synthetic valve to enter a pivotal trial (Xplore2/Pivotal) in July ...

ByXELTIS BV


Xeltis receives €15M funding from EIC Accelerator

Xeltis receives €15M funding from EIC Accelerator

The EIC funding comprises €2.5 millions in grants and up to €12.5 millions in equity and will support Xeltis’ clinical trial program for its XABG device, the first-ever restorative Coronary Artery Bypass Graft (CABG). XABG is a restorative, synthetic blood vessel device that turns into a living blood vessel when ...

ByXELTIS BV


Marizyme Inc. Announces Results of GOAL Study Presented at 7th Annual International Coronary Congress

Marizyme Inc. Announces Results of GOAL Study Presented at 7th Annual International Coronary Congress

Emmert (German Heart Center and Charite Universitatsmedizin, Berlin Germany) Friday, December 3 at the 7th Annual International Coronary Congress in New York City. The GOAL Study is an independent investigator observational clinical study to assess the role of vascular graft /storage solutions on myocardial protection during coronary ...

ByMarizyme, Inc.


Marizyme Announces Expansion of Patent Portfolio Into Several Key Territories

Marizyme Announces Expansion of Patent Portfolio Into Several Key Territories

These patents protect Marizyme’s flagship commercial product DuraGraft®, a first-in-class CE marked intra-operative graft storage solution. DuraGraft® protects vascular grafts against ischemic injury during bypass surgeries by reducing the incidence of complications associated with vein graft failure, leading to ...

ByMarizyme, Inc.


Xeltis lands €15 million European financing from EIB

Xeltis lands €15 million European financing from EIB

” Xeltis’ devices are vascular grafts and heart valves designed to turn into living valves and vessels by harnessing the body’s natural healing process and by facilitating tissue formation once implanted. ...

ByXELTIS BV


Marizyme is Pleased to Announce the Appointment of David Barthel as CEO

Marizyme is Pleased to Announce the Appointment of David Barthel as CEO

The Company's flagship product, DuraGraft®, is an intra-operative vascular graft storage solution that inhibits endothelial damage and leads to improved clinical outcomes by reducing the incidence of complications associated with vein graft failure in bypass surgery. DuraGraft enhances coronary artery ...

ByMarizyme, Inc.


First Patient Enrolled in U.S. STAR-T Pivotal Trial Evaluating the DrugSorb-ATR Antithrombotic Removal System to Remove Ticagrelor During Cardiothoracic Surgery

First Patient Enrolled in U.S. STAR-T Pivotal Trial Evaluating the DrugSorb-ATR Antithrombotic Removal System to Remove Ticagrelor During Cardiothoracic Surgery

Taylor, Chief of the Division of Cardiac Surgery and Director of Coronary Revascularization and site Principal Investigator at the University of Maryland Medical Center. ...

ByCytoSorbents Corporation


XyloCor Therapeutics Completes Oversubscribed $41.9 Million Series A Financing To Advance Novel Gene Therapy Pipeline For Coronary Artery Disease

XyloCor Therapeutics Completes Oversubscribed $41.9 Million Series A Financing To Advance Novel Gene Therapy Pipeline For Coronary Artery Disease

An estimated one million people suffer from refractory angina in the United States. About Coronary Artery Bypass Graft Surgery (CABG) CABG is a procedure used to treat coronary artery disease — the narrowing or blockage of the blood vessels that supply oxygen and nutrients to the heart ...

ByXyloCor Therapeutics


Xeltis initiates first-ever pivotal trial of a synthetic restorative pulmonary heart valve

Xeltis initiates first-ever pivotal trial of a synthetic restorative pulmonary heart valve

In addition to its restorative pulmonary valve, Xeltis has developed the first-ever restorative synthetic coronary artery bypass graft (CABG) to have shown successful long-term results in long preclinical trials and the first-ever restorative synthetic vascular access graft for patients that need ...

ByXELTIS BV


Marizyme Announces New Distribution and Channel Partnership for Chilean Market with Abdera

Marizyme Announces New Distribution and Channel Partnership for Chilean Market with Abdera

"We are excited to partner with Marizyme and bring this pivotal product DuraGraft to the Chilean health care market," said Konrad Ziller, Managing Director for Abdera. "DuraGraft will enhance coronary artery bypass grafting (CABG) surgical outcomes by significantly reducing major adverse cardiac events such as repeat ...

ByMarizyme, Inc.


Marizyme, Inc. Appoints Veteran Business Executive Julie Kampf to Board

Marizyme, Inc. Appoints Veteran Business Executive Julie Kampf to Board

(OTCQB:MRZM), a publicly traded global biotechnology company developing products to reduce the burden of ischemia-reperfusion injury in tissue grafting, organ transplant, and other surgical indications, announced today that it has named veteran business executive Julie Kampf as an Independent Member of its Board of Directors. ...

ByMarizyme, Inc.


Marizyme, Inc. Strengthens Senior Management Team with Two Appointments: Roger Schaller EVP, Commercial Operations and Amy Chandler, EVP, Regulatory Affairs and Quality Management Systems

Marizyme, Inc. Strengthens Senior Management Team with Two Appointments: Roger Schaller EVP, Commercial Operations and Amy Chandler, EVP, Regulatory Affairs and Quality Management Systems

(OTCQB:MRZM), a publicly traded global biotechnology company developing products to reduce the burden of ischemia-reperfusion injury in tissue grafting, organ transplant, and other surgical indications, announced today that it has added two life science industry veterans to its senior management team. ...

ByMarizyme, Inc.


Marizyme Announces Approval for DuraGraft in India

Marizyme Announces Approval for DuraGraft in India

Abel Alexander, Regency Lifesciences CEO, said, "This approval and licensure represents a significant step toward providing this novel treatment to the estimated 60,000 Coronary Artery Bypass Graft Surgeries per year." About CABG and DuraGraft When patients with heart disease undergo CABG surgery, free vein or ...

ByMarizyme, Inc.


Advanced Bifurcation Systems Announces First Closing of Series A Financing

Advanced Bifurcation Systems Announces First Closing of Series A Financing

Mehran Khorsandi and medical devices engineer Henry Bourang, ABS is positioned to solve one of the most technically challenging problems – the treatment of coronary bifurcation lesions - that has eluded the medical device world since coronary stents were first implanted in humans in 1986. Coronary bifurcation lesions are prevalent in about ...

ByAdvanced Bifurcation Systems


XyloCor Therapeutics Doses Patients in Phase 1/2 Trial Evaluating Novel Gene Therapy XC001 in Refractory Angina

XyloCor Therapeutics Doses Patients in Phase 1/2 Trial Evaluating Novel Gene Therapy XC001 in Refractory Angina

The trial will enroll patients who are not responding to medication and are unsuitable for coronary artery bypass graft or percutaneous coronary intervention. XC001 is an investigational novel gene therapy designed to activate naturally occurring biological pathways to improve blood flow to areas of the heart not ...

ByXyloCor Therapeutics


Bilirubin, which eliminates inflammation... Bilix, the world`s first drug

Bilirubin, which eliminates inflammation... Bilix, the world`s first drug

The disease that Bilix has targeted is ischemic reperfusion injury caused by organ transplantation, myocardial infarction, coronary artery bypass grafting, and stroke. In the case of myocardial infarction, it occurs after a patient undergoes a stent procedure. ...

ByBilix Co., Ltd.


tiakis (formerly Proteo Biotech AG) Elafin Enters the Clinic For Subcutaneous Use In Pulmonary Arterial Hypertension

tiakis (formerly Proteo Biotech AG) Elafin Enters the Clinic For Subcutaneous Use In Pulmonary Arterial Hypertension

Following the completion of two Phase II surgery trials in ECS and coronary artery bypass graft surgery, and a final European Medicines Agency advice letter, a European pivotal trial with Elafin in ECS is in preparation. ...

Bytiakis BIOTECH AG

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