Cytokine Interleukin Articles & Analysis: Older
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Data showed no dose-limiting toxicities, GvHD or CAR T-related encephalopathy syndrome (CRES). There was one Grade 1 cytokine release syndrome (CRS) event and three patients experienced Grade 3 or 4 treatment-related blood disorders. ...
While secreted cytokines are well known to stimulate the immune system to fight solid tumors, they are often associated with systemic toxicity. ...
Cytokines, including interleukins, interferons, tumor necrosis factors, and chemokines, can play key pro- and anti-inflammatory roles in vivo through a variety of biochemical pathways and interactions. ...