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Drug Resistant Articles & Analysis
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Unfortunately, a growing number of these infections involve drug-resistant Shigella. The four species of Shigella listed by the CDC include: Shigella sonnei (the most common species in the United States) Shigella flexneri Shigella boydii Shigella dysenteriae “Shigella spreads easily, and it can be transmitted from one person to another, or through ...
Combined with nanotechnology, "smart" drugs can actively target tumors by binding to corresponding receptors on tumor cells through interactions with phenotype-specific ligands conjugated to the delivery vehicle. ...
Profacgen, a leading provider of custom biotechnology services, is pleased to announce significant updates to its Antimicrobial Peptides (AMPs) Services, enhancing its capabilities to support the growing demand for alternative therapies in the fight against drug-resistant pathogens. As antibiotic resistance continues to pose a global health ...
The rise of antibiotic-resistant bacteria has driven renewed interest in alternative treatments, including phage therapy. A recent study by Yang, F., et al (2024) explores the potential of bacteriophage therapy for treating multi-drug resistant Mycobacterium tuberculosis (Mtb) infections using humanized mouse models. ...
Antibacterial Serum Preparation Bacterial infections remain a significant concern globally, and the emergence of antibiotic-resistant strains has heightened this challenge. CD Formulation addresses this urgent issue with its antibacterial serum preparation services. ...
As recently as 2022, the agency reports there were 536 confirmed TB cases, including some involving multi-drug resistant (MDR) TB, and that 100% of NYC neighborhoods had at least one TB case. ...
Darolutamide, which is jointly developed by Bayer and Orion Corporation, is an oral androgen receptor inhibitor indicated for the treatment of men with non-metastatic castration-resistant prostate cancer (nmCRPC), who are at high risk of developing metastatic disease and for the treatment of men with metastatic hormone-sensitive prostate cancer (mHSPC). ...
ByBayer AG
It plays a crucial role in drug design and screening, as it enables modeling and prediction of interactions between proteins and small molecules, allowing customers to better understand drug mechanisms of action and optimize candidate compounds. ...
Antiprogestins act as Progesterone Receptor (PgR) antagonists. Novel and promising class of drugs to overcome endocrine resistance associated with ESR1 mutations. ...
Candida auris is an emerging multidrug-resistant microorganism that was first identified in 2009 in Asia. It has quickly become a cause of severe infections around the world, including in the United States according to the Centers for Disease Control and Prevention (CDC). ...
Starton Therapeutics Inc., (the “Company”) a clinical stage biotechnology company announced today results from a 28-day efficacy study of STAR-LLD continuous subcutaneous (SC) infusion versus intraperitoneal (IP) lenalidomide in immunomodulatory drug (IMiD)-resistant RPMI CB.17 SCID mice. In this preclinical study: continuous delivery of lenalidomide ...
“This study demonstrates the power of using Cellworks personalized therapy biosimulation to gain insight into individual patient mutanome, drug resistance pathways and novel biomarkers that determine their drug response and resistance to better inform treatment decisions for MDS ...
This preventative approach will allow Lumen to develop an inexpensive, biologic drug cocktail against the most frequent, multi-drug resistant infecting pathogens. The therapeutic product would be administered and be designed to mitigate risks of antibiotic-resistant infections in resource constrained settings such as battlefield ...
Drug therapy is one of the major modalities for cancer treatment. However, drug resistance may reveal whether it is chemotherapy drugs, targeted drugs, or immunotherapy drugs. Once drug resistance (especially multidrug resistance) is developed, ...
These sequencing technologies are also tools for understanding biochemical interactions between prokaryotes and phages and have been widely used in the food industry and medical research. For example, multiple drug resistance (MDR) has risen dramatically, and phage therapy may be an effective way to treat bacterial infections. ...
The jointly developed therapy features a micro-infusion device that tightly controls drug delivery to a region of the brain for patients with medically refractory epilepsy. ...
Importantly, photodisinfection is effective against drug-resistant pathogens and does not cause resistance-formation, both distinct advantages over antibiotics. ...
“Overuse of antibiotics over decades has caused adaptation in many microbes, and we now see multidrug resistance (MDR) evolving into extensive drug resistance (XDR) in bacteria, rendering even the most powerful drugs we have ineffective,” stated Dr. ...
However, only a minority of patients that get these drugs respond to them and the responses that are seen are often not durable. ...
Sequana Medical NV (Euronext Brussels: SEQUA) (the “Company” or “Sequana Medical“), a pioneer in the treatment of drug-resistant fluid overload in liver disease, heart failure and cancer, today announces the appointment of Alexandra Clyde as an independent Non-Executive Director of the Company. ...