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Drug Use Articles & Analysis: Older
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Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the human disease are crucial. In this context, a recent study by Petersen et al (2024) has made significant strides in validating a well-known IPF mouse ...
Typically, the structures of such polymers are designed to reduce their dispersion in solution, thereby improving their stability and controllability. They’re widely used as drug carriers mainly because of their ability to efficiently carry and release drug molecules, thereby improving drug bioavailability and therapeutic ...
Polymer Microspheres The polymer microspheres range in diameter from 1 to 200 microns and can be loaded with different drugs or bioactive molecules depending on the application. The microspheres can be injected or implanted into the target tissue or organ, allowing the drug to be released locally with minimal systemic effects. Polymeric microspheres are widely ...
Molecular docking is a key technique used in drug discovery and development, and it involves computationally predicting the binding of small molecules with the protein of interest. ...
VeriSIM Life has been awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) grant for $255,908 to conduct research and development (R&D) work on rapid repurposing and translation of approved and investigational drugs for COVID-19 using its patented artificial intelligence (AI) driven biosimulation platform, BIOiSIM. ...
PEG lipids, also known as PEGylated lipids, are mainly used in drug delivery systems; hence, they are highly favored in the field of biomedicine and pharmacy. ...
” Cellworks Precision Drug Development: Pre-clinical Stage Biomarker Development: Cellworks uses cell line data and retrospective patient data to discover novel biomarkers for investigational agents, which can improve drug success rates by prospectively identifying patients who will respond to an agent. ...
Lenalidomide, as an oral immunomodulatory drug, revealed a good safety profile. Parecoxib Sodium Alfa Chemistry offers high-quality parecoxib sodium as API to support the amide prodrug of the cyclooxygenase II (COX-2)-selective inhibitor, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, which has anti-inflammatory, analgesic, and antipyretic activities. ...
Preclinical studies completed prior to EMERALD indicate that the compound has the potential for use as a single agent or in combination with other therapies for the treatment of breast cancer. ...
(Nasdaq: LIXT), a clinical-stage drug discovery company developing pharmacologically active drugs for use in cancer treatment, today announced that it has closed a registered direct offering with certain institutional and accredited investors for $5.8 million of common stock. ...
VeriSIM Life's drug discovery and development decision engine, BIOiSIM, predicts the probability of a drug candidate to treat or cure illnesses or diseases using its unique Translational Index™ scoring technology which allows smarter decision-making on the best therapeutic molecules to eliminate or select for further research. ...
(“BRIM,” TPEx 6885) is pleased to announce that the US Food and Drug Administration (FDA) has granted Orphan Drug Designation (ODD) for BRM424 in the treatment of neurotrophic keratitis (NK), a rare degenerative eye disease which causes very severe cornea damage and can lead to loss of sight. ...
LB-P8, a novel drug being developed by LISCure Biosciences, Inc. (LISCure) as a treatment for Primary Sclerosing Cholangitis (PSC), has been designated as an orphan drug by the US FDA. On December 1, 2022, the US FDA notified LISCure of the orphan drug designation of LB-P8, LISCure's microbiome novel ...
Particular support for decolonisation of pathogens which is the approach taken by its XF-73 Nasal programme Destiny Pharma plc (AIM: DEST), a clinical stage innovative biotechnology company focused on the development of novel medicines that can prevent life-threatening infections, today reports on the publication of findings from the US Food and Drug ...
Phase 1 studies show improvement in cognitive factors, consistent with therapeutic potential of CY6463 to improve key features in neurological diseases CY6463 favorable tolerability and safety profile was confirmed Ariana Pharma, a leading Artificial Intelligence (AI) drug development company, in collaboration with Cyclerion Therapeutics, presented today safety and pharmacodynamic results ...
But the epidural name only refers to using the epidural space of the spine to administer pain relief drugs. ...
Appropriate drug formulation is a prerequisite for successful drug development. CD Formulation, a highly specialized CRO service provider, recently announced its capability of offering one-stop pharmaceutical formulation solutions that can make drug development faster, easier, and more cost-effective. Drug formulation, or ...
Fractional carbon dioxide laser treatment, in the operation process, mainly uses the scanning fractional method to directly emit laser light, and then a special burning area will be formed on the surface of the skin, and each laser is emitted by multiple high-energy lasers It is composed of pulses, which can directly penetrate the skin surface, penetrate deep into the dermis ...
Choosing the most appropriate delivery system has tremendous benefits, including but not limited to controlled release of drugs, enhanced drug targeting, improved solubility and bioavailability of drugs. In the past decade, several new drug delivery systems have been formulated, in the hope to provide promising alternative routes ...
Ariana Pharma, the leading Al-driven precision medicine company, has announced the first comprehensive blarcamesine pathway analysis impact using extensive data from the ANAVEX®2-73-PDD-001 Parkinson’s Disease Dementia (PDD) clinical study. Initial results were presented by Ariana Pharma at the Alzheimer’s Association International Conference (AAIC 2022) in San Diego, in ...