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Electroporation Articles & Analysis
13 news found
Techniques such as iontophoresis, sonophoresis, and electroporation leverage electrical, sound, and thermal energy to improve skin permeability. ...
Clinical evidence suggests that any section of the prostate can be treated with the NanoKnife System’s irreversible electroporation technology5, whereas many other focal treatments are usually confined to one section due to the mechanism of action6. ...
Currently, health insurance companies in the Netherlands do not reimburse for Focal Therapy treatment options (ultrasound ablation (HIFU or TULSA) and irreversible electroporation (IRE)) because the methods have not yet been proven as effective. ...
Furthermore, common non-viral vector transgene methods include electroporation, calcium phosphate precipitation, and liposomal delivery. ...
Surgnova was glad to support the FIRST IRE procedures in Croatia with Dophi™ N3000 Electroporation System for patients with liver metastasis! Dophi N3000 Electroporation System is designed for tumor ablation with advanced precision, safety and reliability. Powered by Irreversible Electroporation (IRE) technology, Dophi™ N3000 can ...
This is achieved by delivering a DNA plasmid using Ichor’s TriGrid® 2.0 electroporation delivery device to enhance the uptake and presentation of cancer antigens to harness high avidity T cell responses. ...
ByScancell
INO-4800 is composed of a precisely designed DNA plasmid that is administered intradermally followed by electroporation using a proprietary smart device, which delivers the DNA plasmid directly into cells in the dermis of the skin and is intended to produce a well-tolerated immune response. ...
Trial participants will be randomized to either INO-4201 or placebo (4:1 ratio) and will receive an intradermal injection followed by electroporation using INOVIO's CELLECTRA® 2000 smart delivery device. ...
“With funding from NIAID, our goal is to apply our novel, non-viral delivery platform, the µVS Delivery SystemTM, to engineer antigen-specific Tregs and demonstrate their utility as a therapeutic to prevent GvHD in preclinical models and as a scalable alternative to viral- and electroporation-based cell manufacturing.” The team at Indee Labs has made multiple ...
Now, with an updated core unit and even more intuitive software, the next generation 4D-Nucleofector® Platform delivers flexibility and the same trusted performance with even greater ease of use. Electroporation, the method by which DNA, RNA or protein is introduced into cells through an electrical pulse to change their genotype or phenotype, is an important tool with a ...
INOVIO Fourth Quarter and Year-End 2020 Highlights On March 1, 2021, INOVIO announced that it met primary and secondary efficacy endpoints among all evaluable subjects for the REVEAL 1 (Randomized Evaluation of VGX-3100 and Electroporation for the treatment of Cervical HSIL) trial. This trial is one of two ongoing pivotal, randomized, double-blind, multi-center, ...
We’re excited to be supported by the NCI to develop our novel, non-viral gene delivery system called the µVS Delivery SystemTM to insert transgenes for CAR-T and TCR-T cell products at clinical scale at a fraction of the cost of the current approaches using viruses with improved T cell function relative to electroporation. Ultimately, our goal is to make these ...
The Farapulse platform employs an ablation modality based on pulsed electric fields, also referred to as irreversible electroporation, that generates zones of ablated cardiac tissue to interrupt the irregular electrical signals that can cause AF. ...