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Histology Articles & Analysis
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Chronic Obstructive Pulmonary Disease (COPD) is a global health burden characterized by persistent airflow limitation and progressive lung damage. Despite extensive research, translating findings from bench to bedside remains a challenge. Precision Cut Lung Slices (PCLS) have emerged as a versatile tool in COPD research, offering unique advantages for understanding disease mechanisms and ...
It’s designed for use in various histological techniques such as immunohistochemistry (IHC) and in situ hybridization (ISH), and other routine procedures. ...
Additionally, Creative Diagnostics provides valuable data on viral disease progression, histology, immunohistochemistry, immunoassays, flow cytometry, cellular infiltration, cytokines, viral titers, LD50 studies, and vaccine/treatment efficacy. ...
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...
The dissertation found that DMS can be used to identify the most common brain tumour samples based on genetic profiling and different histology with considerable accuracy ex vivo. In the future, DMS could provide an alternative to the current method of histopathological analysis of frozen sections. ...
Multimodal: Aggregates data from the radiomics and genomics modules, along with processed clinical, biological, and histological data, to train and verify predictive models at the individual patient level. ...
Idiopathic pulmonary fibrosis (IPF) remains a devastating condition with limited treatment options, often leading to a grim prognosis. However, a recent study by Milman-Krentsis (2024) offers a beacon of hope, demonstrating the potential of lung cell transplantation as a therapeutic intervention for lung fibrosis. Utilizing two distinct mouse models—one treated with bleomycin and another ...
For example, the Multiple Parts of Artery Tissue and Atherosclerosis Tissue Microarray, 30 Cases, 22 Cores (Catalog # CSCT001) consist of various sections of artery tissue and atherosclerosis tissue and can be used in IHC, ISH and other routine histology procedures. This tissue microarray includes various artery tissues (coronary, aorta, etc.) and atherosclerosis samples. ...
In the realm of pulmonary research, the search to understand complex lung conditions has led to the development of various animal models. Among these, a new murine model from Tsijis et al stands out for its potential to investigate flow-induced pulmonary hypertension (PH) and compensatory lung growth (CLG). This blog outlines this innovative model, its significance, and the method of ...
NBCT044) can be used for IHC, ISH and other routine histology procedures. This tissue microarray is created using head and neck cancer samples and tongue tissue, and it includes 57 cases of squamous cell carcinoma, 3 cases of undifferentiated carcinoma, 1 case of sarcomatoid carcinoma, 8 cases of metastatic squamous cell carcinoma, 7 cases of tongue tissue, 2 cases of salivary ...
CD Biosciences has developed an optimized antibody labeling method that allows researchers to achieve uniform labeling on thick tissue while maintaining histological integrity. Upon request, CD Biosciences’ research team can use immersion objectives, light sheet microscopes and other imaging methods to perform 3D image analysis on larger tissues. ...
While most studies focused on Gd presence in brain, the current study evaluated the skin of animal foot pads for Gd presence and neuro-histological changes after multiple GBCA exposure. No signs for small fiber neuropathy in the skin of the foot pads were observed. ...
ByBayer AG
This test also did not show evidence of motor or sensory nerve damage after injection with liposomal bupivacaine at a dose 10-times higher than free bupivacaine. Histologically, signs of neural damage could be observed with lidocaine. Nerves injected with Bupigel showed mild signs of inflammation and small residues of hydrogel in granulomas, indicating a long residence time of ...
The procedure is well tolerated by patients under topical anesthesia and is associated with mild swelling, no perianal discharge, and no bleeding, and remucosalization is noted to occur within 2 weeks."2 Because hemorrhoid tissue and the membranous head of the inferior turbinate bear a histologic similarit~ we set out to determine whether infrared coagulation of the inferior ...
Further, this clinical research shows that the Perimeter OCT images correlate to histological results, with a process that does not interfere with surgical procedures or final pathology. ...
In addition to the benefits of the inertial vacuum, the COOLFREQUENCY® millicurrents, which are high-intensity electrical impulses of very short duration that do not counteract the action of cold, contribute to the biostimulation of the plica with a consequent tightening effect and improve skin texture. Histological examinations and ultrasound analysis show that the use of ...
“Elucid has developed a plaque analysis software based on ground truth histology which is different from Hounsfield unit-based thresholding algorithms available from other companies,” said Todd Villines, MD, Chief Medical Officer, Elucid. ...
ByElucid
In a prior large animal study consisting of 41 skeletally mature sheep, biomechanical testing was performed to show both the immediate and sustained adhesive strength of Tetranite. Histological and histomorphometric analysis was also conducted to evidence the osteointegration of the cranial flaps over a two-year period. ...
” * The NAFLD Activity Score (NAS) is a widely accepted scoring system developed by the NASH Clinical Research Network for use in clinical trials. The score is based on histological assessment of liver biopsies and is comprised of a sum of steatosis, ballooning, and lobular inflammation component ...
As compared with the vehicle treated group, zevaquenabant shows a statistically significant reduction in the Ashcroft score, the primary endpoint in this study, measured by a standardized scale assessing fibrosis histologically. Dr. Glenn Crater, CMO at Inversago pointed out: “These encouraging results obtained using a well-accepted preclinical model for lung fibrosis show ...