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In Vitro Skin Models Articles & Analysis

17 news found

Myelotracker joins Bertin’s Bioreagent portfolio

Myelotracker joins Bertin’s Bioreagent portfolio

We are proud to introduce Myelotracker®, a peptide-based probe. This unique technology specifically targets lactoferrin, a major protein stored in neutrophil granules, making it possible to visualize and study these immune cells with unmatched precision. Unlike many existing tools, Myelotracker does not activate neutrophils, preserving their natural physiological state and ensuring reliable ...

ByBertin Technologies


BIOtechNOW featured IVS’s participating BIO Innovation Zone

BIOtechNOW featured IVS’s participating BIO Innovation Zone

BIOtechNOW featured IVS’s participating BIO Innovation Zone Later this month in Philadelphia at the BIO International Convention, BIO will be partnering with the National Institutes of Health (NIH) and the National Science Foundation (NSF) to host the 2nd annual, newly-expanded BIO Innovation Zone. The Zone will feature Small Business Innovation Research (SBIR) funded early-stage biotech ...

ByInvivoSciences, Inc. (IVS)


Full-Scale PROTAC In Vivo Evaluation Services to Facilitate PROTAC Drug R&D

Full-Scale PROTAC In Vivo Evaluation Services to Facilitate PROTAC Drug R&D

In the process of drug development, the evaluation of drug effectiveness is one of the keys to determining whether prodrugs can sufficiently reach the market stage. BOC Sciences, as a professional contract research organization, can take care of the PROTAC in vivo evaluation workload for clients with a transparent project process and comprehensive evaluation reports to facilitate their PROTAC ...

ByBOC Sciences


TCT 2017 Poster Shows Impact of Strut Thickness on Thrombogenicity in BRS

TCT 2017 Poster Shows Impact of Strut Thickness on Thrombogenicity in BRS

ArterioSorb has been shown to show decreased acute thrombus formation compared to thicker strut bioresorbable scaffolds (BRS) in an in-vitro model. Shengjie Lu PhD, of the National Heart Research Institute and National Heart Centre Singapore, presented a moderated poster at TCT 2017 in Denver, showing the impact of BRS strut thickness on the formation of thrombus. Shengjui, from Nicolas ...

ByArterius Limited


MatTek Enters Distribution Agreement and Strategic Partnership with Cell4Pharma

MatTek Enters Distribution Agreement and Strategic Partnership with Cell4Pharma

MatTek Life Sciences will distribute Cell4Pharma’s ciPTEC renal cells and utilize the technology in the development of a new in vitro kidney model. MatTek Life Sciences, a Boston-area tissue engineering company and a member of the BICO Group, announced today it has entered into a distribution agreement and strategic partnership with Cell4Pharma, a ...

ByBICO - The Bio Convergence Company


Creative Medical Technology Signs Master Collaboration Agreement with the University of Miami to Accelerate Development of ImmCelz Supercharged Autologous Immunotherapy Platform

Creative Medical Technology Signs Master Collaboration Agreement with the University of Miami to Accelerate Development of ImmCelz Supercharged Autologous Immunotherapy Platform

Creative Medical Technology Holdings, Inc. ("Creative Medical Technology" or the "Company") (NASDAQ: CELZ), a leading commercial stage biotechnology company focused on a regenerative approach to immunotherapy, urology, neurology, and orthopedics, today announced that it has signed a Master Collaboration Agreement with the University of Miami to accelerate development of the Company's ImmCelz® ...

ByCreative Medical Technology Holdings, Inc. (CELZ)


Gain Therapeutics Presents Preclinical Data On Its Structurally Targeted Allosteric Regulators In GBA1 Gaucher Disease At The WORLDSymposium 2022

Gain Therapeutics Presents Preclinical Data On Its Structurally Targeted Allosteric Regulators In GBA1 Gaucher Disease At The WORLDSymposium 2022

Study results demonstrate GBA1-targeted allosteric regulators increase GCase protein levels, reduce the production of inflammatory cytokines, and improve key lysosomal functions BETHESDA, Md., Feb. 08, 2022 (GLOBE NEWSWIRE) -- Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”), a biotechnology company transforming the drug discovery paradigm with structurally targeted allosteric ...

ByGain Therapeutics, Inc.


Prellis Biologics Announces Collaboration and License Agreement with Bristol Myers Squibb

Prellis Biologics Announces Collaboration and License Agreement with Bristol Myers Squibb

Prellis Biologics, Inc. (Prellis), a Bay Area biotechnology company, announced today that it has entered into a multi-target drug discovery collaboration and licensing agreement with Bristol Myers Squibb utilizing Prellis Biologics’ first-in-class externalized human immune system (EXIS) based on human lymph node organoids (LNO). The collaboration leverages Prellis’ EXIS platform that ...

ByPrellis Biologics, Inc.


Prellis Biologics Launches In Vitro Human Antibody Discovery Platform, Announces $14.5 Million Series B Investment, Key Executive Hires

Prellis Biologics Launches In Vitro Human Antibody Discovery Platform, Announces $14.5 Million Series B Investment, Key Executive Hires

Prellis Biologics announced today that it has closed a $14.5 million Series B financing round, led by Celesta Capital and current investor Khosla Ventures Prellis will use the proceeds to advance its Externalized Immune System (EXIS™) platform, a first-in-class in vitro, fully human antibody discovery, and vaccine screening workflow. “The EXIS platform offers unprecedented in vitro ...

ByPrellis Biologics, Inc.


Prellis Biologics Launches In Vitro Human Antibody Discovery Platform, Announces $14.5 Million Series B Investment, Key Executive Hires

Prellis Biologics Launches In Vitro Human Antibody Discovery Platform, Announces $14.5 Million Series B Investment, Key Executive Hires

Prellis Biologics announced today that it has closed a $14.5 million Series B financing round, led by Celesta Capital and current investor Khosla Ventures Prellis will use the proceeds to advance its Externalized Immune System (EXIS™) platform, a first-in-class in vitro, fully human antibody discovery, and vaccine screening workflow. “The EXIS platform offers unprecedented in vitro ...

ByPrellis Biologics, Inc.


Stem Pharm Senior Scientist, Joshua Zimmermann, Gives a Talk on Biomaterials for 3D Applications at SELECT BIO’s “Introduction to Implementing 3D Culture Models” Webinar, Sponsored by Promega

Stem Pharm Senior Scientist, Joshua Zimmermann, Gives a Talk on Biomaterials for 3D Applications at SELECT BIO’s “Introduction to Implementing 3D Culture Models” Webinar, Sponsored by Promega

Through control of properties such as substrate mechanical stiffness and adhesion ligand presentation, materials can be designed that enable more physiologically relevant extracellular environments and better direct cellular behaviors within 3D models. At Stem Pharm, we are applying these principles to design PEG-based hydrogels for the development of in vitro neural models. ...

ByStem Pharm, Inc


Lonza and CN Bio Announce Distribution Agreement Providing Prevalidated Hepatocytes for Use on Innovative Organ-on-a-chip Range

Lonza and CN Bio Announce Distribution Agreement Providing Prevalidated Hepatocytes for Use on Innovative Organ-on-a-chip Range

Through a new distribution agreement, Lonza will supply a selection of cells to be prequalified for use in CN Bio’s innovative PhysioMimixTM Organ-On-a-Chip (OOC) range of Single- and Multi-Organ Microphysiological Systems (MPS) The companies share a common goal of developing and supplying advanced cell models that better reflect an in vivo environment to improve drug discovery accuracy ...

ByLonza Group Ltd


Eligo Presents Preclinical Data Demonstrating for the First Time that Gut Microbiome Modulation via Delivery of CRISPR Nuclease Impacts Disease Progression

Eligo Presents Preclinical Data Demonstrating for the First Time that Gut Microbiome Modulation via Delivery of CRISPR Nuclease Impacts Disease Progression

Eligo Bioscience SA, a Paris, France-based microbiome engineering company, today announced that the Company presented preclinical data on its lead drug candidate, EB003, for the treatment of severe diarrhea induced by shiga-toxin (Stx) producing E. coli (STEC, leading to Hemolytic Uremic Syndrome), at the 14th Annual CRISPR 2021 meeting held June 1-10, 2021. The data presented further supports ...

ByEligo Bioscience


Molecular Genetics and Metabolism Publishes Primary Pharmacology Data Supporting HemoShear’s HST5040 as a Potential Treatment for Methylmalonic Acidemia (MMA) and Propionic Acidemia (PA)

Molecular Genetics and Metabolism Publishes Primary Pharmacology Data Supporting HemoShear’s HST5040 as a Potential Treatment for Methylmalonic Acidemia (MMA) and Propionic Acidemia (PA)

HemoShear Therapeutics, Inc., a clinical stage company developing treatments for rare metabolic disorders, today announced the publication of in vitro pharmacology data in the journal Molecular Genetics and Metabolism, demonstrating that the oral small molecule HST5040 may be effective in treating Methylmalonic Acidemia (MMA) and Propionic Acidemia (PA). The company has initiated the HERO (HElp ...

ByHemoShear Therapeutics, Inc.


Axial Biotherapeutics Announces a Research Grant Award from The Michael J. Fox Foundation for the Development of an Enteric Nervous System Model to Assess Novel Parkinson’s Disease Therapeutics

Axial Biotherapeutics Announces a Research Grant Award from The Michael J. Fox Foundation for the Development of an Enteric Nervous System Model to Assess Novel Parkinson’s Disease Therapeutics

Axial Biotherapeutics, a biotechnology company dedicated to building a unique class of gut-targeted therapeutics for neurodegenerative diseases and neurodevelopmental disorders, today announces it has received a research grant of $440,000 from The Michael J. Fox Foundation for Parkinson’s Research (MJFF) through its Therapeutic Pipeline Program. The award will enable development of a novel ...

ByAxial Therapeutics Inc.


Superiority vs gold standard demonstrated by in-vitro model

Superiority vs gold standard demonstrated by in-vitro model

Biofilm creation - among others - is one of the most important factors linked to infections and almost the only one that can be measured through simulation. T-Control demonstrated superiority vs gold standard, i.e. significant differences were observed between the biofilm quantity generated on the product´s surface. This result reinforces the hypothesis that T-Control, with it´s ...

ByRethink Medical S.L.


Agilent Technologies Thought Leader Award Supports Dr. Paul Watkins, Hamner-UNC Institute for Drug Safety Sciences

Agilent Technologies Thought Leader Award Supports Dr. Paul Watkins, Hamner-UNC Institute for Drug Safety Sciences

Agilent Technologies Inc. (NYSE: A) today announced that Dr. Paul B. Watkins, international drug safety expert and director of the Hamner-University of North Carolina Institute for Drug Safety Sciences, has received an Agilent Thought Leader Award in recognition of his ongoing work developing integrated methods to predict drug-induced liver injury (DILI). This award continues Agilent's support ...

ByAgilent Technologies, Inc.

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