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Insulin Therapy Articles & Analysis

18 news found

Updated results from clinical trial with Diamyd presented today at diabetes conference

Updated results from clinical trial with Diamyd presented today at diabetes conference

Although research categorizes LADA as autoimmune diabetes, the disease is still in most cases treated according to the guidelines for type 2 diabetes. LADA patients are usually not insulin dependent at diagnosis, but for most patients, insulin therapy is required within a few years of diagnosis. About Diamyd Medical Diamyd Medical develops ...

ByDiamyd Medical AB


Five-month results from Diamyd trial in LADA published in peer-reviewed scientific journal

Five-month results from Diamyd trial in LADA published in peer-reviewed scientific journal

Although research categorizes LADA as autoimmune diabetes, the disease is still in most cases treated according to the guidelines for type 2 diabetes. LADA patients are usually not insulin dependent at diagnosis, but for most patients, insulin therapy is required within a few years of diagnosis. About Diamyd Medical Diamyd Medical develops ...

ByDiamyd Medical AB


Promising topline results for intralymphatic Diamyd in patients with LADA

Promising topline results for intralymphatic Diamyd in patients with LADA

Although research categorizes LADA as autoimmune diabetes, the disease is still in most cases treated according to the guidelines for type 2 diabetes. LADA patients are usually not insulin dependent at diagnosis, but for most patients, insulin therapy is required within a few years of diagnosis. About Diamyd Medical Diamyd Medical develops ...

ByDiamyd Medical AB


GI Dynamics Announces Final Data from the ENDO Trial, a Multicenter Study Demonstrating the Potential Use of EndoBarrier to Treat Type II Diabetes and Obesity.

GI Dynamics Announces Final Data from the ENDO Trial, a Multicenter Study Demonstrating the Potential Use of EndoBarrier to Treat Type II Diabetes and Obesity.

Analysis revealed that the EndoBarrier System met overall glycemic control efficacy and SAE related device removal safety endpoints, while also providing clinically significant weight loss, and comorbidity improvement. “Insulin therapy is associated with poor long-term outcomes in patients with type 2 diabetes mellitus and obesity, and bariatric surgery is ...

ByGI Dynamics, Inc.


First patient enrolled in Diamyd Medical`s Phase III trial Diagnode-3

First patient enrolled in Diamyd Medical`s Phase III trial Diagnode-3

The patients included in the trial are between 30 and 70 years old, have been diagnosed with LADA within the last 18 months and are not yet on insulin therapy. The Sponsor of the trial is the Norwegian University of Science and Technology with Ingrid K Hals as Sponsor's representative. ...

ByDiamyd Medical AB


Fractyl Health Receives Reimbursement Authorization in Germany for Revita DMR® System

Fractyl Health Receives Reimbursement Authorization in Germany for Revita DMR® System

Revita has already received a CE Mark in Europe to improve glycemic control in patients with inadequately controlled T2D on antidiabetic agents and/or long-acting insulin therapy. German hospitals may now negotiate full reimbursement from the national health insurance system for its use in their patients in clinical studies and/or real-world evidence generation ...

ByFractyl Health


Fractyl Health Provides Initial Clinical Update on Open-Label REVITA-T2Di

Fractyl Health Provides Initial Clinical Update on Open-Label REVITA-T2Di

Per protocol, insulin therapy will be re-introduced, if and when necessary, to help patients achieve good glycemic control. ...

ByFractyl Health


Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

The trial is now enrolling patients with type 2 diabetes who are currently on insulin therapy at the following locations: Saint Joseph’s Medical Center in Paterson, N.J.; The Academic Medical Center in Amsterdam; Tulane Medical Center in New Orleans; Baylor St. ...

ByFractyl Health


Modular Medical Expands Executive Team with Appointment Of Lynn O`Connor Vos as New CEO

Modular Medical Expands Executive Team with Appointment Of Lynn O`Connor Vos as New CEO

(OTCQB:MODD), a development-stage insulin pump company focused on providing insulin delivery without complexity to increase pump adoption and reduce the burden of diabetes care for clinicians and individuals living with diabetes, today announced the expansion of its executive team with the appointment of Lynn O'Connor Vos as its new Chief Executive Officer. ...

ByModular Medical, Inc.


Zucara Therapeutics Doses First Patients in Phase 1b Trial of ZT-01

Zucara Therapeutics Doses First Patients in Phase 1b Trial of ZT-01

Toronto, Canada, July 27, 2021 – Zucara Therapeutics Inc., a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has dosed the first patients in its Phase 1b trial of ZT-01. ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Successfully Completes Single and Multiple Ascending Dose Phase 1 Trial of ZT-01

Zucara Therapeutics Successfully Completes Single and Multiple Ascending Dose Phase 1 Trial of ZT-01

(“Zucara” or the “Company”), a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has successfully completed a Phase 1 study evaluating single and multiple ascending doses of ZT-01. ...

ByZucara Therapeutics Inc.


Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

The trial, called REVITA-T2Di, will evaluate the ability of a single Revita DMR treatment to allow patients currently on insulin therapy but with inadequate glycemic control to achieve durable insulin-free glycemic control. ...

ByFractyl Health


Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

In the INSPIRE study, 16 insulin-treated patients with type 2 diabetes (T2D) underwent a single treatment with Revita DMR after which they ceased insulin therapy and began treatment with GLP-1RA and lifestyle counseling. At six months after Revita DMR treatment, 11 out of 16 patients (69%) remained off insulin ...

ByFractyl Health


Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

Toronto, Canada, September 29, 2020 – Zucara Therapeutics Inc., a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has dosed the first subject in its Phase 1 trial of ZT-01. “Initiation of our Phase 1 study of ZT-01, which has been our goal since ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

Zucara Therapeutics Inc., a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has dosed the first subject in its Phase 1 trial of ZT-01. “Initiation of our Phase 1 study of ZT-01, which has been our goal since establishing the Company in 2014, is a ...

ByZucara Therapeutics Inc.


Fractyl Announces FDA IDE Approval to Begin Pivotal Study of Revita DMR for Insulin-Treated Patients with Type 2 Diabetes

Fractyl Announces FDA IDE Approval to Begin Pivotal Study of Revita DMR for Insulin-Treated Patients with Type 2 Diabetes

Revita T2Di pivotal study to evaluate the ability of Revita DMR, the first non-drug, non-surgical, disease-modifying therapy, to eliminate need for insulin injections in T2D; enrollment expected to begin in late 2020 LEXINGTON, Mass., June 3, 2020 — Fractyl Laboratories Inc. ...

ByFractyl Health


Zucara Therapeutics Announces US$21 Million Series A Financing

Zucara Therapeutics Announces US$21 Million Series A Financing

The proceeds from the financing will fund Phase 1 and Phase 2 clinical trials of ZT-01, Zucara’s first-in-class drug candidate designed to prevent hypoglycemia in Type 1 Diabetes (T1D), a frequent, unintended consequence of insulin therapy for people with T1D and other types of insulin-dependent diabetes. ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Announces US$21 Million Series A Financing

Zucara Therapeutics Announces US$21 Million Series A Financing

The proceeds from the financing will fund Phase 1 and Phase 2 clinical trials of ZT-01, Zucara’s first-in-class drug candidate designed to prevent hypoglycemia in Type 1 Diabetes (T1D), a frequent, unintended consequence of insulin therapy for people with T1D and other types of insulin-dependent diabetes. ...

ByZucara Therapeutics Inc.

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