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Intestinal Mucosa Articles & Analysis

11 news found

Creative Enzymes Offers Products to Support the Clinical and Research Use of Liver Function Evaluation

Creative Enzymes Offers Products to Support the Clinical and Research Use of Liver Function Evaluation

Creative Enzymes provides a variety of enzyme products to support the research and development of liver functionality tests, such as the following hot products: Native Microorganism Malate Dehydrogenase Native Microorganism D-lactate dehydrogenase Native Saccharomyces cerevisiae Alcohol Dehydrogenase Native Bovine intestinal mucosa Alkaline Phosphatase Native ...

ByCreative Enzymes


Fecal biomarkers - diagnostic possibilities in the context of inflammatory bowel disease

Fecal biomarkers - diagnostic possibilities in the context of inflammatory bowel disease

Here, it accounts for up to 60% of the cytosolic protein content. During intestinal inflammation, neutrophilic granulocytes migrate from the bloodstream into the intestinal lumen (Roseth et al., 1997). ...

ByImmundiagnostik AG


AVROBIO Reports Positive Data From Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis, Including New Interim Data on Neurocognitive Measures

AVROBIO Reports Positive Data From Phase 1/2 Clinical Trial of Investigational Gene Therapy for Cystinosis, Including New Interim Data on Neurocognitive Measures

Preliminary data suggest that post gene therapy, functional cystinosin has been produced throughout the body as evidenced by clinical measures in multiple tissues, including the eyes, skin, gastrointestinal mucosa and neurocognitive system. No adverse events (AEs) related to the drug product have been reported to date. ...

ByTectonic Therapeutic, Inc.


AVROBIO Reports Fourth Quarter and Fiscal Year 2021 Financial Results and Provides Business Update

AVROBIO Reports Fourth Quarter and Fiscal Year 2021 Financial Results and Provides Business Update

Reduction in number of cystine crystals as measured in skin and intestinal mucosa biopsies observed across these three patients. A fourth patient was infused in November 2021. ...

ByTectonic Therapeutic, Inc.


Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

An outpatient endoscopic procedure, Revita DMR resurfaces the lining of the upper intestine (duodenal mucosa). Revita DMR has been studied in clinical trials involving close to 300 patients. ...

ByFractyl Health


Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

It will evaluate the efficacy of Revita DMR (duodenal mucosal resurfacing), a first-in-class intervention targeting the role of the intestine in metabolic disease. The trial’s primary endpoint is the percentage of patients who are able to achieve target glycemic control (HbA1c less than or equal to 7%) without the need for insulin at 24 weeks, comparing Revita DMR to the ...

ByFractyl Health


Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

The outpatient procedure uses heat to resurface the lining of the upper intestine. In the INSPIRE study, 16 insulin-treated patients with type 2 diabetes (T2D) underwent a single treatment with Revita DMR after which they ceased insulin therapy and began treatment with GLP-1RA and lifestyle counseling. ...

ByFractyl Health


Fractyl Raises $55 Million in Series E Financing to Advance Revita DMR for Type 2 Diabetes

Fractyl Raises $55 Million in Series E Financing to Advance Revita DMR for Type 2 Diabetes

” The Revita DMR treatment harnesses breakthrough insights in intestinal biology and aims to reset key metabolic pathways, including insulin resistance, to reverse metabolic disease. This same-day, outpatient endoscopic procedure uses heat to resurface the lining of the upper intestine (duodenal mucosa) in a minimally invasive, outpatient ...

ByFractyl Health


Fractyl Announces FDA IDE Approval to Begin Pivotal Study of Revita DMR for Insulin-Treated Patients with Type 2 Diabetes

Fractyl Announces FDA IDE Approval to Begin Pivotal Study of Revita DMR for Insulin-Treated Patients with Type 2 Diabetes

About the RevitaⓇ DMR Treatment The Revita DMR treatment harnesses breakthrough insights in intestinal biology and aims to reset key metabolic pathways, including insulin resistance, to prevent and even reverse metabolic disease progression. This same-day, outpatient endoscopic procedure uses heat to resurface the lining of the upper intestine (duodenal ...

ByFractyl Health


Discovery of an anti-inflammatory molecule produced by gut bacteria

The researchers also showed that MAM’s effect was due to its ability to reduce the levels of certain immune system compounds in the intestinal mucosa that cause inflammation. It therefore seems that the bacteria that live in our guts protect us using the same tools as medical professionals. ...

ByINRA - French National Institute of Agronomical Research


ASTM E787 - 81(2011) Standard Specification for Disposable Glass Micro Blood Collection Pipets

ASTM E787 - 81(2011) Standard Specification for Disposable Glass Micro Blood Collection Pipets

Heparin shall be the ammonium salt isolated from the lungs or intestinal mucosa of beef or pork origin and shall meet the specified heparin potency. ...

ByASTM International

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