Kidney Toxicity Articles & Analysis
2 news found
If positive, the interim analysis may serve as the basis for Vertex to seek accelerated approval of VX-147 in the U.S. for patients with AMKD. About APOL1-Mediated Kidney Disease APOL1-mediated kidney disease is a form of chronic kidney disease caused by mutations in the APOL1 gene. ...
"It enables our team to identify metabolomic safety biomarkers of drug-induced renal toxicity and the mechanisms by which these toxicities occur. This research will lead us to identifying at-risk patients and exploring the use of concomitantly administered medicines as protectants against drug-induced renal damage. It could have a major effect on improving drug ...