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Muscle Tissue Articles & Analysis

11 news found

Inversago Pharma Doses First Patient in Phase 2 Trial of INV-202, an Oral, Peripherally-acting CB1 Inverse Agonist, in Patients with Diabetic Kidney Disease

Inversago Pharma Doses First Patient in Phase 2 Trial of INV-202, an Oral, Peripherally-acting CB1 Inverse Agonist, in Patients with Diabetic Kidney Disease

It is specifically designed to preferentially block CB1 receptors in peripheral tissues such as the kidneys, gastro-intestinal tract, liver, pancreas, adipose tissues, muscles, lungs and other organs. ...

ByInversago Pharma


Inversago Pharma receives IND clearance for Phase 2 trial of INV-202 in Diabetic Kidney Disease

Inversago Pharma receives IND clearance for Phase 2 trial of INV-202 in Diabetic Kidney Disease

It is specifically designed to preferentially block CB1 receptors in peripheral tissues such as the kidneys, gastro-intestinal tract, liver, pancreas, adipose tissues, muscles, lungs and other organs. ...

ByInversago Pharma


Inversago Pharma presents data on INV-202 in Diabetic Nephropathy at the ERA 2022 Congress

Inversago Pharma presents data on INV-202 in Diabetic Nephropathy at the ERA 2022 Congress

It is specifically designed to preferentially interact with peripheral CB1 receptors located in the kidneys, gastro-intestinal tract, liver, pancreas, adipose tissues, muscles, lungs and other organs, thus aiming at a safe and effective therapeutic approach without the known liabilities of centrally-acting CB1 blockers. ...

ByInversago Pharma


AVROBIO Announces Preclinical Gene Therapy Data for Pompe Disease at American Society of Gene and Cell Therapy (ASGCT) Annual Meeting

AVROBIO Announces Preclinical Gene Therapy Data for Pompe Disease at American Society of Gene and Cell Therapy (ASGCT) Annual Meeting

AVR-RD-03, AVROBIO’s gene therapy for Pompe disease, includes a proprietary Glycosylation-Independent Lysosomal Targeting (GILT)-tag which consists of a short peptide sequence linked to the therapeutic protein and is designed to enhance uptake in targeted tissues. “Pompe disease is a progressive, life-limiting neuromuscular disorder caused by the accumulation of ...

ByTectonic Therapeutic, Inc.


Longeveron Announces Publication of Lomecel-B Phase 2b Trial Design in Journal of Frailty and Aging

Longeveron Announces Publication of Lomecel-B Phase 2b Trial Design in Journal of Frailty and Aging

Clinically, frailty manifests as a combination of symptoms that includes loss of muscle and decreased strength, slowed walking, low activity and energy levels, poor endurance, nutritional deficiencies, weight loss and fatigue. ...

ByLongeveron, Inc.


XyloCor Therapeutics Completes Oversubscribed $41.9 Million Series A Financing To Advance Novel Gene Therapy Pipeline For Coronary Artery Disease

XyloCor Therapeutics Completes Oversubscribed $41.9 Million Series A Financing To Advance Novel Gene Therapy Pipeline For Coronary Artery Disease

The investigational gene therapy will be administered directly to the muscle tissue of the heart by an experienced cardiac surgeon. The EXACT Trial was initiated in 2020 and is ongoing at top cardiovascular research sites across the United States. About Chronic Refractory Angina Chronic angina pectoris occurs when the heart muscle does not ...

ByXyloCor Therapeutics


Profound Medical Receives FDA HDE Approval for Sonalleve

Profound Medical Receives FDA HDE Approval for Sonalleve

Computed tomography(CT)-guided radiofrequency ablation (RFA), the most commonly used osteoid osteoma treatment, requires drilling through muscle and soft tissue into bone, and also exposes the patient to radiation from the imaging necessary to guide the probe that is inserted to heat and destroy tumor tissue. Sonalleve® is an innovative ...

ByProfound Medical Corp.


Fibralign Awarded SBIR Phase IIS from Department of Defense

Fibralign Awarded SBIR Phase IIS from Department of Defense

This two-year grant provides $996,609 in funding to continue advancing Fibralign’s development of a novel treatment of volumetric muscle loss. Project Title: Aligned Nanofibrillar Scaffold Activated with HGF-mmRNA in Combination with Minced Muscle Graft for Treating Volumetric Muscle Loss (VML) Injury This new project builds on ...

ByFibralign Corporation


Just the (Fascia) Facts: Why Myofascial Release is so Beneficial

Just the (Fascia) Facts: Why Myofascial Release is so Beneficial

Fascia is the head-to-toe connective tissue that runs throughout the entire body. The fascia encompasses all the body’s internal structures, connecting everything together, even penetrating the muscles, organs and fatty tissues, and connecting bones to muscles and organs to each other. ...

ByDSmedi, Inc.


Infections at Maryland Cosmetic Surgery Center Result in Closure

The Centers for Disease Control and Prevention (CDC) states, “Severe, sometimes life-threatening, GAS disease may occur when bacteria get into parts of the body where bacteria usually are not found, such as the blood, muscle, or the lungs. These infections are termed "invasive GAS disease." ...

BySussex Environmental Health Consultants


Renowned Laboratory Identifies Flesh Eating Bacteria

Renowned Laboratory Identifies Flesh Eating Bacteria

Necrotizing fasciitis, also known as "the flesh-eating bacteria", is a rapidly progressing disease which destroys muscles, fat and skin tissue. Flesh eating bacteria releases toxins that destroy the surrounding tissue. ...

ByEMSL Analytical, Inc.

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