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Nucleic Acid Articles & Analysis: Older
106 news found
Nucleosides, the building blocks of nucleic acids, aren’t only simple building blocks for RNA and DNA. ...
For accurate quantification of nucleic acids, techniques such as quantitative PCR (qPCR) or digital droplet PCR (ddPCR) are recommended, particularly for determining the final library quantity. ...
This strategic move is aimed at addressing the rising global demand for Lipid Nanoparticles (LNPs), which are vital for nucleic acid drug delivery, especially in mRNA-based therapies and vaccines. ...
The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client ...
BOC Sciences, the world-leading chemical manufacturer and technical solution provider, recently added a series of exosome technologies to meet diverse needs in nucleic acid delivery. Exosomes are tiny vesicles secreted by cells, capable of transporting molecules from one cell to another. ...
Biotinylation, a widely used biological technique, involves the covalent attachment of biotin to biomolecules such as proteins, peptides, and nucleic acids. This technique plays a crucial role in various research fields, including molecular biology, biochemistry, and diagnostics. ...
They can be used for the delivery of small molecule drugs, biologics, vaccines, and even nucleic acids. By bypassing the gastrointestinal tract and avoiding first-pass metabolism, microneedle-based drug delivery allows for higher bioavailability and improved therapeutic outcomes. ...
By introducing bacteriophage SP6 into the transcriptional promoter and a completely artificial E01 sequence selected from a randomized nucleic acid sequence pool into the translational enhancer, an mRNA with high translational activity can be produced, and protein synthesis efficiency can be maximized. ...
The biological reagents previously launched by Alfa Chemistry encompass transilluminator, proteomic products (i.e., Protein Marker/Ladder, Western Substrate, Protein Staining Reagent, OneStep Blocker, UltraScence TMB ELISA Substrate), genomic products (i.e., DNA Marker/Ladder, Staining Reagent, Agarose, PCR Reagent, RNA Reagent, Real-Time PCR Reagent), and nucleic ...
Both appointments come as etherna’s new strategy is gaining significant traction globally. etherna is enabling a growing number of life science and pharma companies to accelerate their pursuits into the fast-growing nucleic acid sector by leveraging the Company’s industry-leading proprietary RNA-based chemistry, its custom LNP delivery platforms, and ...
ByeTheRNA
Traditional nucleic acid detection methods require trained operators and sophisticated instrumentation, with signal reading and detection times often taking hours. ...
These chemicals have inclusive applications in mRNA vaccines and therapeutics, RNA therapeutics (ASO, siRNA, miRNA, Aptamer), nucleic acid detection, gene sequencing and editing (CRISPR-Cas9), and oligonucleotide synthesis, etc. ...
The company also offers various custom services, including chemical surface-functionalization, fluorescent modification, antibody immobilization, as well as nucleic acid and oligo conjugation to meet client ...
Everyone unanimously approved and applauded the exhibited products which included the PreMed 5200 liquid chromatography tandem mass spectrometry system, GeneTOF 3100 nucleic acid mass spectrometry system, ClinCap 1000 fully automated capillary electrophoresis instrument, and MSFLO benchtop mass spectrometry flow cytometer among a few.Focusing on clinical ...
Mullis in the early 1980s, this approach is considered the gold standard in nucleic acid analysis. RT-PCR can obtain DNA from the RNA template when working with RNA as a starting material. ...
Notably, it also provides assay development services for biomarkers, including proteins, nucleic acids, carbohydrates, and lipids, as well as building diagnostic kits that access enzyme activity, protein-protein interactions, nucleic acid-protein interactions, and inhibitor characterization. ...
Lipid nanoparticles (LNPs) overcome the major obstacles to the development of mRNA vaccines, enabling the safe and efficient delivery of nucleic acids. Therefore, it has now become the most common non-viral vectors used in clinical practice. Alfa Chemistry now provides four key excipients for LNPs that can be used in nucleic acid ...
This includes the spectrum of tests necessary for the detection and containment of infectious diseases, such as COVID-19, including sequencing, nucleic acid detection, antigen detection and antibody detection. The platform was also designed with the scalability to provide the solution for rapid, low-cost whole genome sequencing in precision medicine, for treating ...
ReCode is leveraging its SORT LNP platform and nucleic acid technologies to expand its pipeline with therapeutics that use mRNA-mediated replacement and gene correction in target organs with precision targeting of disease-relevant cells. ...
ByBayer AG
By utilizing the Lipofection and Magnetofection transfection techniques, these reagents are suitable for all types of nucleic acids, including plasmid DNA, linearized DNA, siRNA, oligonucleotides, double-stranded RNA, mRNA, and shRNA. Gene expression and therapy involves the introduction of foreign nucleic acids into target cells ...