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Opioid Use Articles & Analysis

23 news found

Tris Pharma Presents Data Reinforcing Limited Abuse Potential of Investigational Pain Therapy Cebranopadol at the 2023 PAINWeek Conference

Tris Pharma Presents Data Reinforcing Limited Abuse Potential of Investigational Pain Therapy Cebranopadol at the 2023 PAINWeek Conference

Cebranopadol is the first and only dual nociceptin/orphanin FQ peptide (NOP) receptor and µ-opioid peptide (MOP) receptor agonist (dual-NMR) analgesic in clinical development for the treatment of moderate to severe pain, as well as opioid use disorder (OUD). ...

ByTris Pharma, Inc.


Tris Pharma Reports Positive Topline Data from Clinical Study of Investigational Pain Therapy Cebranopadol Showing Significantly Less Potential for Abuse Versus Tramadol and Oxycodone

Tris Pharma Reports Positive Topline Data from Clinical Study of Investigational Pain Therapy Cebranopadol Showing Significantly Less Potential for Abuse Versus Tramadol and Oxycodone

These data suggest that cebranopadol has a lower potential for abuse versus both C-II and C-IV opioids. Cebranopadol is a novel, dual nociceptin/orphanin FQ peptide (NOP) receptor and μ-opioid peptide (MOP) receptor agonist in development for the treatment of moderate to severe pain. ...

ByTris Pharma, Inc.


XPhyto Pursues Potential Application of its Oral Dissolvable Biosensor Inflammation Test for Buprenorphine-related Dental Disease

XPhyto Pursues Potential Application of its Oral Dissolvable Biosensor Inflammation Test for Buprenorphine-related Dental Disease

Certain buprenorphine medicines prescribed to treat opioid use disorder (“OUD”) and pain have been recently associated with numerous serious oral health problems requiring medical intervention. ...

ByXPhyto Therapeutics Corporation


gammaCore (Non-Invasive Vagus Nerve Stimulation; nVNS) Reduces Symptoms of Acute Withdrawal in Patients with Opioid Use Disorder

gammaCore (Non-Invasive Vagus Nerve Stimulation; nVNS) Reduces Symptoms of Acute Withdrawal in Patients with Opioid Use Disorder

The study, conducted with the support of Emory and Georgia Tech University, was sponsored by a grant from the National Institute on Drug Addiction (NIDA), part of the National Institutes of Health (NIH), through NIH Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative. Substance use is an escalating crisis in the United States, with ...

ByelectroCore, Inc.


Personalized Methadone Dispensing Device for Take-Homes Receives NIDA Grant

Personalized Methadone Dispensing Device for Take-Homes Receives NIDA Grant

Called the COPA system, the proprietary, hand-held drug dispensing device is meant to provide at-home methadone administration as part of treatment for opioid use disorder (OUD). The system delivers the liquid methadone, and includes remote monitoring to make sure precise doses of medication are delivered. ...

ByBerkshire Biomedical


Landmark Survey by Stagwell`s The Harris Poll Estimates More Than 72.3 Million U.S. Adults Suffer from Chronic Low Back Pain - Greater than Arthritis, Diabetes, or Heart Disease and with Debilitating Impact on Quality of Life

Landmark Survey by Stagwell`s The Harris Poll Estimates More Than 72.3 Million U.S. Adults Suffer from Chronic Low Back Pain - Greater than Arthritis, Diabetes, or Heart Disease and with Debilitating Impact on Quality of Life

"The fact that more than a third are not being told what is causing their pain, such as LSS or an enlarged ligament, makes it more difficult to treat that pain. It is also alarming that opioid use is still high in people with back pain while other treatments such as minimally invasive procedures are not playing more of a role given the latest treatment ...

ByVertos Medical, Inc.


BioXcel Therapeutics Announces NIH NIDA Grant to Columbia University to Support Further Studies of BXCL501 (Sublingual Dexmedetomidine) for Treating Opioid Withdrawal

BioXcel Therapeutics Announces NIH NIDA Grant to Columbia University to Support Further Studies of BXCL501 (Sublingual Dexmedetomidine) for Treating Opioid Withdrawal

Multi-year-funded award to support a 160-patient, randomized-controlled study in patients undergoing opioid withdrawal treatment Over 142 million opioid prescriptions dispensed in the U.S. in 20201 More than 1.7 million people in the U.S. suffered from substance use disorders related to prescription opioid pain relievers in ...

ByBioXcel Therapeutics, Inc.


Berkshire Biomedical Awarded NIH Research Grant to Support Continued Development of the COPA System for Automated at Home Methadone Administration

Berkshire Biomedical Awarded NIH Research Grant to Support Continued Development of the COPA System for Automated at Home Methadone Administration

Berkshire's receipt of this award reflects the NIH's belief in the strength of the technology behind COPA and its potential to significantly increase access to Opioid Treatment Programs for persons suffering from Opioid Use Disorder (OUD) by dramatically increasing the number of persons being allowed to utilize take home therapy," stated John ...

ByBerkshire Biomedical


Murphy Highlights Norwalk’s Biowave as “Innovator of the Month”

Murphy Highlights Norwalk’s Biowave as “Innovator of the Month”

BioWave’s technology has helped professional and college athletes, veterans and others suffering from chronic pain, get closer to a pain-free life and return to daily activities without the use of opioids. BioWave recently introduced a new patent pending product family called BioWraps which are wearable compression electrode garments that are paired with ...

ByBioWave Corporation


Berkshire Biomedical, Developers of COPA,  Featured as a 2022 Top Texas Tech Startup in StartupCity Magazine

Berkshire Biomedical, Developers of COPA, Featured as a 2022 Top Texas Tech Startup in StartupCity Magazine

Timberlake continued, “It is important to note that non-adherence is linked to hospital admissions, worse healthcare outcomes and higher healthcare costs. The initial intended use for COPA will include the delivery of opioids for the treatment of chronic pain and the delivery of methadone in Medication Assisted Therapy for the treatment of ...

ByBerkshire Biomedical


Oncomfort appoints Karl Schweitzer to Chairman of the Board

Oncomfort appoints Karl Schweitzer to Chairman of the Board

With this appointment, Oncomfort brings on board the experienced leadership to guide the organisation in its global expansion and significant knowledge for the realization of the company’s strategy in Digital Sedation™ Oncomfort, Belgian start-up innovating Digital SedationTM for relieving patients’ pain and anxiety using clinically proven therapeutic sessions ...

ByOncomfort


Nevro Announces FDA Approval for Expanded Labeling for its 10 kHz High Frequency Spinal Cord Stimulation System for Treatment of Non-Surgical Refractory Back Pain (NSRBP)

Nevro Announces FDA Approval for Expanded Labeling for its 10 kHz High Frequency Spinal Cord Stimulation System for Treatment of Non-Surgical Refractory Back Pain (NSRBP)

REDWOOD CITY, Calif., Jan. 19, 2022 /PRNewswire/ -- Nevro Corp. (NYSE: NVRO), a global medical device company that is delivering comprehensive, life-changing solutions for the treatment of chronic pain, today announced receipt of FDA approval for expanded labeling for its Senza® Spinal Cord Stimulation (SCS) System for the treatment of Non-Surgical Refractory Back Pain (NSRBP). This approval ...

ByNevro Corp.


Clinical Data Presented at 2022 North American Neuromodulation Society (NANS) Annual Meeting Reinforce Significant and Durable Benefits of Nevro`s 10 kHz Therapy

Clinical Data Presented at 2022 North American Neuromodulation Society (NANS) Annual Meeting Reinforce Significant and Durable Benefits of Nevro`s 10 kHz Therapy

SENZA-PDN Randomized Controlled Trial Results Demonstrate Significant and Sustained Outcomes with 10 kHz Therapy at 18-Months Follow-Up. SENZA-NSRBP Randomized Controlled Trial Results Show Profound Improvements in Non-Surgical Refractory Back Pain Patients Receiving 10 kHz Therapy Relative to Conventional Medical Management at 12-Months Follow-Up. Both SENZA-PDN and SENZA-NSRBP Studies ...

ByNevro Corp.


Braeburn receives new Complete Response Letter for Brixadi in the US

Braeburn receives new Complete Response Letter for Brixadi in the US

Camurus AB (NASDAQ STO: CAMX) today announced that its US licensee Braeburn has received a Complete Response Letter (CRL) from the US Food and Drug Administration (FDA) for its updated New Drug Application (NDA) for Brixadi (buprenorphine) extended-release injections for the treatment of opioid use disorder. The CRL is a result ...

ByCamurus AB


The European Medicines Agency accepts application to extend the Buvidal indication to include treatment of chronic pain

The European Medicines Agency accepts application to extend the Buvidal indication to include treatment of chronic pain

There is a high unmet medical need in chronic pain, particularly among patients with concomitant opioid use problems. If approved, Buvidal could become an important therapeutic option for the management of chronic pain, adding to the current indication of treating opioid dependence”, says Dr. ...

ByCamurus AB


Tetra Bio-Pharma Announces Positive Initial Clinical Data from Both of its Ongoing Phase 2 Clinical Trials of QIXLEEF™

Tetra Bio-Pharma Announces Positive Initial Clinical Data from Both of its Ongoing Phase 2 Clinical Trials of QIXLEEF™

About Breakthrough Cancer Pain Opioids are the cornerstone of the management of cancer pain. The opioid crisis is serious, and the number of deaths related to overdosing remains elevated (Opioid Basics | CDC's Response to the Opioid Overdose Epidemic | CDC). Tetra's cannabis and cannabinoid-derived product pipeline has the ...

ByTetra Bio-Pharma


Neuropathix, Inc. Wholly Owned Subsidiary Kannalife Sciences, Inc. Awarded $2.97 Million Phase 2 Study Grant from National Institute of Neurological Disorders and Stroke (NINDS)

Neuropathix, Inc. Wholly Owned Subsidiary Kannalife Sciences, Inc. Awarded $2.97 Million Phase 2 Study Grant from National Institute of Neurological Disorders and Stroke (NINDS)

Adding to the equation is the off-label use of opioids and gabapentinoids for chronic and neuropathic pain as a result of the unmet medical need and no FDA approved non-opioid drug to treat chronic and neuropathic pain, specifically Chemotherapy-induced peripheral neuropathy (CIPN). ...

ByNeuropathix, Inc.


Saluda Medical Announces Publication of 24-Month Spinal Cord Stimulation Results with the Evoke® System

Saluda Medical Announces Publication of 24-Month Spinal Cord Stimulation Results with the Evoke® System

Results show ~90% overall back and leg responder rate, ~68% high responder rate, and zero explants due to loss of efficacy ~83% of patients reduced or eliminated opioid use Need for patient re-programming visits nearly eliminated after 12 months Represents the first peer reviewed SCS study to show responder and high responder rate improvement over time Saluda ...

BySaluda Medical Pty Ltd.


Micro-Invasive Carpal Tunnel Release

Micro-Invasive Carpal Tunnel Release

Joseph McGinley of Wyoming recently captured local newspaper and NBC TV news coverage for performing micro-invasive CTR using a unique Augmented Reality (AR) display technology he developed with the University of Wyoming. ...

BySonex Health Inc.


Cardiva Medical Announces Publication of Data From the AMBULATE Pivotal Study in the Journal of the American College of Cardiology: Clinical Electrophysiology

Cardiva Medical Announces Publication of Data From the AMBULATE Pivotal Study in the Journal of the American College of Cardiology: Clinical Electrophysiology

The study showed significant improvements in time to ambulation, total post-procedure time and time-to-discharge eligibility, as well as improved patient satisfaction scores and significantly reduced use of opioid pain medications. Principal investigators and authors of the study include Andrea Natale, M.D., of the Texas Cardiac Arrhythmia Institute; Mintu ...

ByCardival Medical, Inc.

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