Pancreatic Cells Articles & Analysis: Older
15 news found
In contrast to T2D, which is primarily a chronic metabolic disease, in type 1 diabetes the insulin secreting cells of the pancreas are destroyed, which is deemed to be attributable to factors such as genetics and environmental triggers. ...
ByBayer AG
Diabetes drug screening platforms using patient pancreatic islet-like cells generated from induced pluripotent stem ...
Development of a rapid and inexpensive luciferase-based high throughput screening assay to identify compounds that alter pancreatic β cell ...
Engineered pancreatic endocrine cells that report beta cell toxicity for use in high throughput screening ...
The absolute lack of insulin, due to destruction of the insulin producing pancreatic β-cells, is the particular disorder in type 1 diabetes while type 2 diabetes is mainly characterized by the inability of cells to respond to insulin. ...
AMPK regulates cellular events, including cell growth, metabolic reprogramming, and autophagy. AMPK has emerged as a potential therapeutic target for metabolic diseases such as type 2 diabetes and cancer. ...
Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced three abstracts, including two oral presentations and one poster, detailing data on type 1 diabetes (T1D) and its Phase 1/2 trial of VX-880, a stem cell-derived, fully differentiated pancreatic islet cell replacement therapy, have been accepted for presentation during the American ...
Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today provided updates on its Phase 1/2 clinical trial of VX-880, an investigational stem cell-derived, fully differentiated pancreatic islet cell replacement therapy for people with type 1 diabetes (T1D) with impaired hypoglycemic awareness and severe hypoglycemia. ...
The Company currently has a pipeline of five anti-glycan mAbs: SC129, SC134, SC88 and SC27 that target solid tumours including pancreatic, small cell lung, colorectal and gastric, and SC2811 that targets a glycolipid on T cell stem cells. ...
ByScancell
IsletRx is an expanded population of allogeneic stem cells differentiated into functioning insulin producing pancreatic islet cells. ...
Today, French cell therapy company TreeFrog Therapeutics released data showing the mass production of human induced pluripotent stem cells (hiPSC) produced with their proprietary C-Stemâ„¢ technology in 10L bioreactors at the 2021 Annual Meeting of the International Society for Stem Cell Research (ISSCR). ...
Details related to the poster presentation are as follows: Title: A cancer organogram test as a guide for oncology treatments in solid tumors: an analysis of 628 tests in 419 patients First Author: Astrid Margossian, MD, PhD Senior Author: Carla Grandori, MD, PhD Abstract Number: 2602 Poster Session: Developmental Therapeutics— Immunotherapy About PARIS® Test The PARIS® ...
Adenosine has an immune-suppressive effect in tumors, and pre-clinical and early clinical evidence indicates that antagonists of the GPCR family of adenosine receptors are able to relieve that suppression and restore anti-tumor immune cell activity. EXS21546 is a non-furan, selective antagonist of the A2A receptor with low brain penetration. Using EXS21546, we show that activity ...
Never mind better insulin shots or cell implants for diabetics: Betalin Therapeutics has a unique approach. ...
These NCEs will be targeting basal cell carcinoma, pancreatic cancer, and glioblastoma with the ultimate future goal of establishing new standards of care for cancer patients. ...