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Pathology Disease Articles & Analysis

23 news found

Ace Therapeutics Releases Diabetic Mouse Models for Preclinical Diabetes Research

Ace Therapeutics Releases Diabetic Mouse Models for Preclinical Diabetes Research

These models have been specifically designed to enable research on different types of diabetes including type 1, type 2, and gestational diabetes, providing valuable insights into disease mechanisms and potential treatment options. Diabetes mellitus is a chronic, systemic, metabolic disease caused by the long-term combination of genetic factors and ...

ByAce Therapeutics


Circulating Tumor Cell detection by Menarini Group’s CELLSEARCH System leading to genomic profiling of myeloma cells shows potential for non-invasive management of Multiple Myeloma patients at early stages of disease

Circulating Tumor Cell detection by Menarini Group’s CELLSEARCH System leading to genomic profiling of myeloma cells shows potential for non-invasive management of Multiple Myeloma patients at early stages of disease

Researchers at Dana-Farber Cancer Institute showed that enumeration of circulating tumor cells (CTCs) with Menarini Silicon Biosystems’ CELLSEARCH® System and the CELLSERCH® Circulating Multiple Myeloma Cell (CMMC) Test* can be used to monitor and manage patients with Multiple Myeloma (MM) even at asymptomatic precursor stages Menarini Silicon Biosystems, a pioneer of liquid biopsy ...

ByThe Menarini Group


5 Ways OCT Technology Can Benefit Your Practice

5 Ways OCT Technology Can Benefit Your Practice

OCT fundus cameras like the Topcon Maestro2 allow us to see a greater detailed image of the eye to find pathology and manage diseases early.” By cross-cutting the retina in a manner similar to an MRI machine, OCT’s high-resolution imaging creates a 3D map of a patient’s eye, enabling doctors to diagnose eye diseases in a single ...

ByLombart Instrument, Inc.


Cell Apoptosis Kits at Creative Biogene: Efficient and Convenient

Cell Apoptosis Kits at Creative Biogene: Efficient and Convenient

Mitochondrial dysfunction has been linked to a variety of market therapeutics and pathological diseases. Therefore, studying or maintaining mitochondrial health is paramount to cell health. ...

ByCreative Biogene-Mitochondrial Research


Inspirata Unveils New Partnership at the Association of Pathology Chairs (APC) Annual Meeting 2022

Inspirata Unveils New Partnership at the Association of Pathology Chairs (APC) Annual Meeting 2022

Digital pathology and cancer informatics provider Inspirata is proud to announce a new partnership with precision pathology company SpIntellx, further strengthening and diversifying Inspirata’s growing partner ecosystem. ...

ByInspirata, Inc


Altoida Appoints Neuroscience Pioneer Dr. Antontella Santuccione Chadha as Chief Medical Officer

Altoida Appoints Neuroscience Pioneer Dr. Antontella Santuccione Chadha as Chief Medical Officer

Chadha is a medical doctor and internationally recognized expert in clinical pathology, neuroscience, neurological disease, and psychiatric disorders. ...

ByAltoida, Inc.


Axial Therapeutics Announces Participation of its CEO, A. Stewart Campbell, in Longwood Healthcare Leaders Spring MIT Webconference

Axial Therapeutics Announces Participation of its CEO, A. Stewart Campbell, in Longwood Healthcare Leaders Spring MIT Webconference

Harnessing its unique expertise in the microbiome, Axial is developing small molecule drugs with defined mechanisms of action that act on new targets to mitigate the impact of metabolites and bacteria in the gut linked to neurological disorders and disease pathology, progression, and symptoms. The company is advancing a pipeline of “microbial-inspired ...

ByAxial Therapeutics Inc.


Axial Therapeutics’ Scientific Founder Sarkis Mazmanian, Ph.D., to Present Research Highlighting the Gut-Brain Connection in Autism Spectrum Disorder (ASD) at TACA’s Autism Action Conference

Axial Therapeutics’ Scientific Founder Sarkis Mazmanian, Ph.D., to Present Research Highlighting the Gut-Brain Connection in Autism Spectrum Disorder (ASD) at TACA’s Autism Action Conference

About Autism Spectrum Disorder (ASD) According to the Centers for Disease Control and Prevention (CDC), approximately 1 in 44 children has been identified with ASD. ...

ByAxial Therapeutics Inc.


Microbiotica Receives Crohn’s & Colitis Foundation Funding to Develop Ulcerative Colitis Therapeutic

Microbiotica Receives Crohn’s & Colitis Foundation Funding to Develop Ulcerative Colitis Therapeutic

Pre-clinical testing shows that MB310 can address key UC disease pathologies, with the ability to repair the epithelial barrier and restore immune homeostasis. ...

ByMicrobiotica Limited


New Preclinical Research Published in Nature Highlights an Active Role by Microbiome-Derived Metabolites in Brain Function and Anxiety-like Behavior

New Preclinical Research Published in Nature Highlights an Active Role by Microbiome-Derived Metabolites in Brain Function and Anxiety-like Behavior

Earlier studies in animal models were the basis for the foundational concept that metabolites produced by intestinal bacteria can circulate in the bloodstream and affect the pathology, progression, and symptoms of neurodegenerative diseases and neurodevelopmental disorders. Axial Therapeutics was founded based on this research as well as additional preclinical ...

ByAxial Therapeutics Inc.


Axial Therapeutics Raises $37.25 Million in Series C Financing to Advance its Pipeline of Gut-Targeted Small Molecule Drugs for Neurological Diseases and Disorders

Axial Therapeutics Raises $37.25 Million in Series C Financing to Advance its Pipeline of Gut-Targeted Small Molecule Drugs for Neurological Diseases and Disorders

Axial is advancing a pipeline of small molecule drugs with defined mechanisms of action that act on new targets to mitigate the impact of metabolites and bacteria in the gut linked to neurological disease pathology, progression, and symptoms. The company’s drug discovery approach is rooted in the groundbreaking research of its co-founder and chief ...

ByAxial Therapeutics Inc.


miR Scientific Presents Groundbreaking Data on the Exceptional Accuracy of its Prostate Cancer Liquid-Biopsy Test

miR Scientific Presents Groundbreaking Data on the Exceptional Accuracy of its Prostate Cancer Liquid-Biopsy Test

NEW YORK, Sept. 20, 2021 /PRNewswire/ -- Data presented from a cross-validation study at the American Urological Association's (AUA) 2021 Annual Meeting confirms that the miR Sentinel® Prostate Cancer Test can detect and risk-classify prostate cancer at the molecular level with predictive accuracy of over 90%, based on a single urine sample. This validation study follows and confirms the ...

BymiR Scientific, LLC


Creative Biolabs Upgrades Proteomics Technologies for Exosomal Cargo and Biomarker Research

Creative Biolabs Upgrades Proteomics Technologies for Exosomal Cargo and Biomarker Research

They are spherical, bilayered proteolipids and show a diverse mixture of exosomal nucleic acids (mRNA and non-coding RNA), proteins, and lipids, among which exosomal proteins play a key role in the pathological process of various diseases. At Creative Biolabs, proteomics technologies have been improved to determine both qualitative and quantitative features of ...

ByCreative Biolabs


Peer-Reviewed Journal Publishes Analytical Validation Results for the PrecivityAD Blood Test, Which Can Help Clinicians Detect Alzheimer’s Disease

Peer-Reviewed Journal Publishes Analytical Validation Results for the PrecivityAD Blood Test, Which Can Help Clinicians Detect Alzheimer’s Disease

C2N Diagnostics, which offers the PrecivityAD™ blood test that can help detect if certain markers for Alzheimer’s disease are in the brain, now has its analytical validation results available for review. ...

ByC2N Diagnostics


Axial Therapeutics Promotes A. Stewart Campbell to Chief Executive Officer

Axial Therapeutics Promotes A. Stewart Campbell to Chief Executive Officer

“We thank David for his commitment and tireless effort over the past four years, taking Axial from an idea to a company poised to enter Phase 2B in autism and with a robust pipeline of innovative programs in Parkinson’s disease and oncology,” said Dr. Campbell. Axial’s unique focus on targeting the gut as a means to treat CNS diseases and ...

ByAxial Therapeutics Inc.


AB2 Bio and WuXi Biologics Announce Collaboration to Accelerate Commercial-Scale Manufacturing of Tadekinig alfa

AB2 Bio and WuXi Biologics Announce Collaboration to Accelerate Commercial-Scale Manufacturing of Tadekinig alfa

Tadekinig alfa is a novel IL-18 binding protein in pivotal Phase 3 testing for orphan disease IL-18 driven monogenic Hemophagocytic Lymphohistiocytosis (HLH) WuXi Biologics to undertake commercial scale manufacturing to support U.S. market launch AB2 Bio Ltd., a Swiss advanced clinical-stage biotech company developing innovative therapies for the treatment of severe ...

ByAB2 Bio Ltd.


Oligomerix Receives $3.19 Million NIH Commercialization Readiness Pilot Grant for Alzheimer`s Disease Therapy

Oligomerix Receives $3.19 Million NIH Commercialization Readiness Pilot Grant for Alzheimer`s Disease Therapy

“We have generated compelling preclinical evidence that inhibiting tau self-association can significantly reduce pathological downstream insoluble tau aggregate formation which could lead to altering disease progression in tauopathies including AD,” said James Moe, Ph.D., MBA, President and CEO of Oligomerix. ...

ByOligomerix, Inc.


Optos plc, Unveils Silverstone, a Combined Ultra-widefield Retinal Imaging Device and UWF-Guided Swept Source OCT for the Ophthalmic Market

Optos plc, Unveils Silverstone, a Combined Ultra-widefield Retinal Imaging Device and UWF-Guided Swept Source OCT for the Ophthalmic Market

This provides unparalleled UWF guided multimodal imaging in support of detection, investigation and monitoring of retinal disease. Silverstone provides greater imaging functionality and expands the Company’s product portfolio for ophthalmic markets. ...

ByOptos, Inc.


DiamiR Announces Additional $345,000 Funding from the NIH for Development of CogniMIR

DiamiR Announces Additional $345,000 Funding from the NIH for Development of CogniMIR

The award will further support development of the company's targeted diagnostic technology for detection and prediction of progression of Alzheimer's disease (AD). "AD is proving to be an extremely difficult indication to develop treatment for due to its heterogeneity and not well understood causes of the pathology associated with the disease. ...

ByDiamiR


MODAG Launches Out of Stealth Mode with Series A Financing of EUR 12 Million to Develop Treatments for Parkinsonian Disorders, Including Multiple System Atrophy

MODAG Launches Out of Stealth Mode with Series A Financing of EUR 12 Million to Develop Treatments for Parkinsonian Disorders, Including Multiple System Atrophy

Anle138b aims to halt the progression of MSA, an atypical form of Parkinsonism, by addressing the core disease pathology. The financing round was led by Massa Investment AG and will support the corporate growth as well as the clinical development of anle138b, which has already demonstrated the potential to halt MSA progression in preclinical studies. ...

ByMODAG GmbH

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